Search Results - "Fridman Dror, Anna"
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Abnormal morphological and functional nature of bone marrow stromal cells provides preferential support for survival of acute myeloid leukemia cells
Published in International journal of cancer (01-05-2019)“…Hematopoietic progenitors, residing in the bone marrow (BM) niche, are supported by mesenchymal stromal cells (MSCs). Cytogenetic and molecular aberrations in…”
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BND-22, a first-in-class humanized ILT2-blocking antibody, promotes antitumor immunity and tumor regression
Published in Journal for immunotherapy of cancer (01-09-2022)“…BackgroundCancer immunotherapy has revolutionized cancer treatment. However, considering the limited success of immunotherapy to only some cancer types and…”
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Donor cell leukemia: reappearance of gene mutations in donor cells - more than an incidental phenomenon?
Published in Haematologica (Roma) (01-12-2020)Get full text
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Abstract 2846A: CD28 shedding is a novel immune-regulatory mechanism found in cancer patients which directly inhibits anti PD-1 effect
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background The interaction between the CD28 receptor and its B7 ligands has a crucial role in the induction of a potent and persistent anti-tumor T…”
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Donor Cell Leukemia: The Role of Recipient Microenvironment
Published in Blood (29-11-2018)“…Acute myeloid leukemia (AML) is one of the extreme outcomes of age-related clonal hematopoiesis (ARCH). In recent years, data on differences between pre-AML…”
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Donor cell leukemia: reappearance of gene mutations in donor cells - more than an incidental phenomenon?
Published in Haematologica (Roma) (01-12-2020)Get full text
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Abstract 654: CD28 shedding is a novel resistance mechanism to anti PD-1 therapy
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: Resistance mechanisms to anti-PD1 therapy remain poorly understood. Studies have implicated that efficient anti-PD1 therapy relies…”
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