Search Results - "Fridman, Wolf Herman"

Tertiary lymphoid structures in the era of cancer immunotherapy by Sautès-Fridman, Catherine, Petitprez, Florent, Calderaro, Julien, Fridman, Wolf Herman

“…Tertiary lymphoid structures (TLSs) are ectopic lymphoid organs that develop in non-lymphoid tissues at sites of chronic inflammation including tumours. Key…”
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Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer by Bindea, Gabriela, Mlecnik, Bernhard, Tosolini, Marie, Kirilovsky, Amos, Waldner, Maximilian, Obenauf, Anna C., Angell, Helen, Fredriksen, Tessa, Lafontaine, Lucie, Berger, Anne, Bruneval, Patrick, Fridman, Wolf Herman, Becker, Christoph, Pagès, Franck, Speicher, Michael R., Trajanoski, Zlatko, Galon, Jérôme

“…The complex interactions between tumors and their microenvironment remain to be elucidated. Combining large-scale approaches, we examined the spatio-temporal…”
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Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction by MLECNIK, Bernhard, TOSOLINI, Marie, GALON, Jérôme, KIRILOVSKY, Amos, BERGER, Anne, BINDEA, Gabriela, MEATCHI, Tchao, BRUNEVAL, Patrick, TRAJANOSKI, Zlatko, FRIDMAN, Wolf-Herman, PAGES, Franck

“…The prognosis of patients with colorectal cancer has sometimes proved uncertain; thus, the prognostic significance of immune criteria was compared with that of…”
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Prognostic and Predictive Impact of Intra- and Peritumoral Immune Infiltrates by HERMAN FRIDMAN, Wolf, GALON, Jerome, PAGES, Franck, TARTOUR, Eric, SAUTES-FRIDMAN, Catherine, KROEMER, Guido

“…Leukocyte infiltrates into or around tumor cell nests are found in the context of protumorigenic inflammation and anticancer immunosurveillance. Hence, the…”
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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks by Bindea, Gabriela, Mlecnik, Bernhard, Hackl, Hubert, Charoentong, Pornpimol, Tosolini, Marie, Kirilovsky, Amos, Fridman, Wolf-Herman, Pagès, Franck, Trajanoski, Zlatko, Galon, Jérôme

“…We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene…”
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The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome by Remark, Romain, Becker, Christian, Gomez, Jorge E, Damotte, Diane, Dieu-Nosjean, Marie-Caroline, Sautès-Fridman, Catherine, Fridman, Wolf-Herman, Powell, Charles A, Altorki, Nasser K, Merad, Miriam, Gnjatic, Sacha

“…Solid tumors, beyond mere accumulation of cancer cells, form a complex ecosystem consisting of normal epithelial cells, fibroblasts, blood and lymphatic…”
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In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer by Pagès, Franck, Kirilovsky, Amos, Mlecnik, Bernhard, Asslaber, Martin, Tosolini, Marie, Bindea, Gabriela, Lagorce, Christine, Wind, Philippe, Marliot, Florence, Bruneval, Patrick, Zatloukal, Kurt, Trajanoski, Zlatko, Berger, Anne, Fridman, Wolf-Herman, Galon, Jérôme

“…Many patients who present with early-stage colorectal cancer (International Union Against Cancer TNM stages I and II) are nevertheless at high risk of relapse…”
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Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures by DIEU-NOSJEAN, Marie-Caroline, ANTOINE, Martine, LEBECQUE, Serge, FRIDMAN, Wolf-Herman, CADRANEL, Jacques, DANEL, Claire, HEUDES, Didier, WISLEZ, Marie, POULOT, Virginie, RABBE, Nathalie, LAURANS, Ludivine, TARTOUR, Eric, DE CHAISEMARTIN, Luc

“…It has been established that the immune system plays an important role in tumor rejection. There is also compelling evidence that immune responses can develop…”
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Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer by Mlecnik, Bernhard, Tosolini, Marie, Charoentong, Pornpimol, Kirilovsky, Amos, Bindea, Gabriela, Berger, Anne, Camus, Matthieu, Gillard, Mélanie, Bruneval, Patrick, Fridman, Wolf–Herman, Pagès, Franck, Trajanoski, Zlatko, Galon, Jérôme

“…Background & Aims Colorectal cancer is a complex disease involving immune defense mechanisms within the tumor. Herein, we used data integration and…”
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The adaptive immunologic microenvironment in colorectal cancer : A novel perspective by GALON, Jérome, FRIDMAN, Wolf-Herman, PAGES, Franck

“…Colorectal cancer is one of the most common malignancies, often presenting with a poor prognosis. To date, the anatomic extent of disease has been by far the…”
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Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma by PLATONOVA, Sophia, CHERFILS-VICINI, Julien, FRIDMAN, Wolf-Herman, SAUTES-FRIDMAN, Catherine, CREMER, Isabelle, DAMOTTE, Diane, CROZET, Lucile, VIEILLARD, Vincent, VALIDIRE, Pierre, ANDRE, Pascale, DIEU-NOSJEAN, Marie-Caroline, ALIFANO, Marco, REGNARD, Jean-François

“…Both the innate and adaptive immune systems contribute to tumor immunosurveillance in mice and humans; however, there is a paucity of direct evidence of a role…”
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Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence by CAMUS, Matthieu, TOSOLINI, Marie, TRAJANOSKI, Zlatko, HERMAN FRIDMAN, Wolf, GALON, Jérôme, MLECNIK, Bernhard, PAGES, Franck, KIRILOVSKY, Amos, BERGER, Anne, COSTES, Anne, BINDEA, Gabriela, CHAROENTONG, Pornpimol, BRUNEVAL, Patrick

“…A role for the immune system in controlling the progression of solid tumors has been established in several mouse models. However, the effect of immune…”
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Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin by REMARK, Romain, ALIFANO, Marco, FLEJOU, Jean-François, GIBAULT, Laure, VERKARRE, Virginie, REGNARD, Jean-François, PAGES, Olivier-Nicolas, OUDARD, Stéphane, MLECNIK, Bernhard, SAUTES-FRIDMAN, Catherine, FRIDMAN, Wolf-Herman, DAMOTTE, Diane, CREMER, Isabelle, LUPO, Audrey, DIEU-NOSJEAN, Marie-Caroline, RIQUET, Marc, CROZET, Lucile, OUAKRIM, Hanane, GOC, Jeremy, CAZES, Aurélie

“…If immune cells are involved in tumor surveillance and have a prognostic impact in most primary tumors, little is known about their significance in metastases…”
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Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome by Galon, Jérôme, Costes, Anne, Sanchez-Cabo, Fatima, Kirilovsky, Amos, Mlecnik, Bernhard, Lagorce-Pagès, Christine, Tosolini, Marie, Camus, Matthieu, Berger, Anne, Wind, Philippe, Zinzindohoué, Franck, Bruneval, Patrick, Cugnenc, Paul-Henri, Trajanoski, Zlatko, Fridman, Wolf-Herman, Pagès, Franck

“…The role of the adaptive immune response in controlling the growth and recurrence of human tumors has been controversial. We characterized the…”
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Clinical Features of Anti-Factor H Autoantibody-Associated Hemolytic Uremic Syndrome by DRAGON-DUREY, Marie-Agnès, SIDHARTH KUMAR SETHI, LE QUINTREC, Moglie, NIAUDET, Patrick, LOIRAT, Chantal, HERMAN FRIDMAN, Wolf, FREMEAUX-BACCHI, Véronique, BAGGA, Arvind, BLANC, Caroline, BLOUIN, Jacques, RANCHIN, Bruno, ANDRE, Jean-Luc, TAKAGI, Nobuaki, HAE II CHEONG, HARI, Pankaj

“…Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy that associates, in 70% of cases, with genetic or acquired disorders…”
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The prognostic impact of anti-cancer immune response: a novel classification of cancer patients by Bindea, Gabriela, Mlecnik, Bernhard, Fridman, Wolf-Herman, Galon, Jérôme

“…Until now, the anatomic extent of tumor (TNM classification) has been, by far, the most important factor to predict the prognosis of colorectal cancer…”
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Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint monoclonal antibody therapies by Soussan, Sarah, Pupier, Guilhem, Cremer, Isabelle, Joubert, Pierre-Emmanuel, Sautès-Fridman, Catherine, Fridman, Wolf Herman, Sibéril, Sophie

“…The intricate relationship between anti-tumor immunity and autoimmunity is a complex yet crucial aspect of cancer biology. Tumor microenvironment often…”
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Characteristics of tertiary lymphoid structures in primary cancers by Goc, Jérémy, Fridman, Wolf-Herman, Sautès-Fridman, Catherine, Dieu-Nosjean, Marie-Caroline

“…Tumors are sustained by complex networks of interactions between malignant cells, stromal cells and tumor-infiltrating immune cells. These networks differ from…”
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Growth/Differentiation Factor-15 (GDF-15): From Biomarker to Novel Targetable Immune Checkpoint by Wischhusen, Jörg, Melero, Ignacio, Fridman, Wolf Herman

“…Growth/differentiation factor-15 (GDF-15), also named macrophage inhibitory cytokine-1, is a divergent member of the transforming growth factor β superfamily…”
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Humoral complementomics - exploration of noninvasive complement biomarkers as predictors of renal cancer progression by Revel, Margot, Rezola Artero, Mikel, Hamidi, Houcine, Grunenwald, Anne, Blasco, Loris, Vano, Yann A, Marie Oudard, Stephane, Sanchez-Salas, Rafael, Macek, Petr, Rodriguez Sanchez, Lara, Cathelineau, Xavier, Vedié, Benoit, Sautes-Fridman, Catherine, Herman Fridman, Wolf, Roumenina, Lubka T, Dragon-Durey, Marie-Agnes

“…Despite the progress of anti-cancer treatment, the prognosis of many patients with solid tumors is still dismal. Reliable noninvasive biomarkers are needed to…”
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