Search Results - "Friday, Sean"
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NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
Published in Science translational medicine (27-03-2013)“…The early events leading to the development of rheumatoid arthritis (RA) remain unclear, but formation of autoantibodies to citrullinated protein antigens…”
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Journal Article -
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Phospholipase D enzymes facilitate IL-17- and TNFα-induced expression of proinflammatory genes in rheumatoid arthritis synovial fibroblasts (RASF)
Published in Immunology letters (01-06-2016)“…Highlights • Synovial fibroblasts express two types of phospholipase D, PLD1 and PLD2. • PLD regulates production of pro-inflammatory cytokines by synovial…”
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Journal Article -
3
Expression and Function of Aminopeptidase N/CD13 Produced by Fibroblast‐like Synoviocytes in Rheumatoid Arthritis: Role of CD13 in Chemotaxis of Cytokine‐Activated T Cells Independent of Enzymatic Activity
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-01-2015)“…Objective Aminopeptidase N/CD13 (EC 3.4.11.2) is a metalloproteinase expressed by fibroblast‐like synoviocytes (FLS). It has been suggested that CD13 can act…”
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Journal Article -
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Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis
Published in Arthritis research & therapy (12-04-2016)“…Inhibitor of DNA binding 1 (Id1) is a nuclear protein containing a basic helix-loop-helix (bHLH) domain that regulates cell growth by selective binding and…”
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Journal Article -
5
Contribution of extracellular negatively charged residues to ATP action and zinc modulation of rat P2X₂ receptors
Published in Journal of neurochemistry (01-05-2008)“…Two histidines are known to be essential for zinc potentiation of rat P2X₂ receptors, but the chemistry of zinc coordination would suggest that other residues…”
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Journal Article -
6
Contribution of extracellular negatively charged residues to ATP action and zinc modulation of rat P2X 2 receptors
Published in Journal of neurochemistry (01-05-2008)“…Abstract Two histidines are known to be essential for zinc potentiation of rat P2X 2 receptors, but the chemistry of zinc coordination would suggest that other…”
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Journal Article -
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Neutrophil extracellular traps are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis (P4061)
Published in The Journal of immunology (1950) (01-05-2013)“…Abstract The early events leading to the development of rheumatoid arthritis remain unclear but formation of autoantibodies to citrullinated antigens is…”
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Journal Article -
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The role of negatively charged amino acids in channel function, pH potentiation, and zinc modulation of the ATP-gated rat P2X2 receptor
Published 01-01-2008“…P2X receptors are a family of genes encoding seven homologous subunits which form ion channels that are permeable to Na+, K +, and Ca2+ ions upon activation by…”
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Dissertation