Search Results - "Fricker, Nicolai"
-
1
Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model
Published in Molecular cell (27-07-2012)“…The CD95 (Fas/APO-1) death-inducing signaling complex (DISC) is essential for the initiation of CD95-mediated apoptotic and nonapoptotic responses. The CD95…”
Get full text
Journal Article -
2
Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL
Published in The Journal of cell biology (09-08-2010)“…Cellular FADD-like interleukin-1β-converting enzyme inhibitory proteins (c-FLIPs; isoforms c-FLIP long [c-FLIPL], c-FLIP short [c-FLIPS], and c-FLIP Raji…”
Get full text
Journal Article -
3
Dynamics within the CD95 death-inducing signaling complex decide life and death of cells
Published in Molecular systems biology (2010)“…This study explores the dilemma in cellular signaling that triggering of CD95 (Fas/APO‐1) in some situations results in cell death and in others leads to the…”
Get full text
Journal Article -
4
Understanding apoptosis by systems biology approaches
Published in Molecular bioSystems (01-01-2009)“…Apoptosis is a process common to all multicellular organisms. Apoptosis leads to the elimination of cells via a complex but highly defined cellular programme…”
Get more information
Journal Article -
5
Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIP^sub L
Published in The Journal of cell biology (09-08-2010)“…Cellular FADD-like interleukin-1β - converting enzyme inhibitory proteins (c-FLIPs; isoforms c-FLIP long [c-FLIP...], c-FLIP short [c-FLIPS], and c-FLIP Raji…”
Get full text
Journal Article