Search Results - "Fricke‐Galindo, Ingrid"
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Genetics Insight for COVID-19 Susceptibility and Severity: A Review
Published in Frontiers in immunology (01-04-2021)“…Coronavirus disease (COVID-19) presents a broad spectrum of clinical manifestations ranging from an asymptomatic to a severe clinical course. The host genetic…”
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Editorial: The impact of the human genome on interindividual variability in drug response
Published in Frontiers in genetics (2024)Get full text
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Pharmacogenetics Approach for the Improvement of COVID-19 Treatment
Published in Viruses (05-03-2021)“…The treatment of coronavirus disease 2019 (COVID-19) has been a challenge. The efficacy of several drugs has been evaluated and variability in drug response…”
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Severe COVID-19 Patients Show an Increase in Soluble TNFR1 and ADAM17, with a Relationship to Mortality
Published in International journal of molecular sciences (05-08-2021)“…Overproduction of inflammatory cytokines is a keystone event in COVID-19 pathogenesis; TNF and its receptors (TNFR1 and TNFR2) are critical pro-inflammatory…”
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Genomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans
Published in Clinical pharmacology and therapeutics (01-01-2020)“…We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero‐America…”
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IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19
Published in Frontiers in immunology (29-07-2022)“…Interferons (IFNs) are a group of cytokines with antiviral, antiproliferative, antiangiogenic, and immunomodulatory activities. Type I IFNs amplify and…”
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The rs16969968 Tobacco Smoking-Related Single-Nucleotide Variant Is Associated with Clinical Markers in Patients with Severe COVID-19
Published in International journal of molecular sciences (01-06-2023)“…Tobacco smoking is the leading risk factor for many respiratory diseases. Several genes are associated with nicotine addiction, such as and . This research…”
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The Immune Response of OAS1 , IRF9 , and IFI6 Genes in the Pathogenesis of COVID-19
Published in International journal of molecular sciences (01-05-2024)“…COVID-19 is characterized by a wide range of clinical manifestations, where aging, underlying diseases, and genetic background are related to worse outcomes…”
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High Expression Levels of miR-21-5p in Younger Hospitalized COVID-19 Patients Are Associated with Mortality and Critical Disease
Published in International journal of molecular sciences (01-06-2023)“…In COVID-19, critical disease and invasive mechanical ventilation (IMV) increase the risk of death, mainly in patients over 60 years of age. To find the…”
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Variant rs4986790 of toll-like receptor 4 affects the signaling and induces cell dysfunction in patients with severe COVID-19
Published in International journal of infectious diseases (01-01-2024)“…We investigated the expression of toll-like receptor (TLR)-4 on the cell surface of innate and adaptive cells from patients with COVID-19 carrying the…”
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The ACE rs1799752 Variant Is Associated with COVID-19 Severity but Is Independent of Serum ACE Activity in Hospitalized and Recovered Patients
Published in International journal of molecular sciences (21-04-2023)“…This paper assesses the association of the insertion/deletion (angiotensin-converting enzyme) variant (rs1799752 I/D) and the serum ACE activity with the…”
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HLA-G 14-bp variant is associated with exercise-induced oxygen desaturation in the post-COVID-19 condition
Published in ERJ open research (01-07-2024)“…https://bit.ly/3THdx1D…”
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COVID-19 Survivor Patients Carrying the Rs35705950 Risk Allele in MUC5B Have Higher Plasma Levels of Mucin 5B
Published in Current issues in molecular biology (22-07-2022)“…Genetic susceptibility to infectious diseases is partly due to the variation in the human genome, and COVID-19 is not the exception. This study aimed to…”
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Outcome predictors in COVID-19: An analysis of emergent systemic inflammation indices in Mexican population
Published in Frontiers in medicine (21-10-2022)“…The systemic viral disease caused by the SARS-CoV-2 called coronavirus disease 2019 (COVID-19) continues to be a public health problem worldwide. This study is…”
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Genetic variants in ATP2B2 as risk factors for mortality in patients unrelated but not associated with families with severe COVID-19
Published in Heliyon (30-04-2024)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of Coronavirus Disease 2019 (COVID-19). The disease has a wide range of…”
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SERPINE1 rs6092 Variant Is Related to Plasma Coagulation Proteins in Patients with Severe COVID-19 from a Tertiary Care Hospital
Published in Biology (Basel, Switzerland) (14-04-2022)“…An impaired coagulation process has been described in patients with severe or critical coronavirus disease (COVID-19). Nevertheless, the implication of…”
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sRAGE levels are decreased in plasma and sputum of COPD secondary to biomass-burning smoke and tobacco smoking: Differences according to the rs3134940 AGER variant
Published in Heliyon (15-04-2024)“…The receptor for advanced glycation end products (RAGE) and its gene (AGER) have been related to lung injury and inflammatory diseases, including chronic…”
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Association of PADI2 and PADI4 polymorphisms in COVID-19 host severity and non-survival
Published in Heliyon (30-03-2024)“…Enzymes of the peptidylarginine deiminase family (PADs) play a relevant role in the pathogenesis of COVID-19. However, the association of single nucleotide…”
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Exploring the potential benefits of pharmacogenomics in chronic respiratory diseases
Published in Pharmacogenomics (01-04-2023)“…Opportunities for pharmacogenetics implementation in chronic respiratory diseases through the employment of genotype-guided prescriptions in treating…”
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Current pharmacogenomic recommendations in chronic respiratory diseases: Is there a biomarker ready for clinical implementation?
Published in Expert review of respiratory medicine (02-11-2022)“…The study of genetic variants in response to different drugs has predominated in fields of medicine such as oncology and infectious diseases. In chronic…”
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