Search Results - "Frick, Lloyd"

Filtration improves the performance of a high-throughput screen for anti-mycobacterial compounds by Cheng, Nancy, Porter, Melissa A, Frick, Lloyd W, Nguyen, Yvonne, Hayden, Jennifer D, Young, Ellen F, Braunstein, Miriam S, Hull-Ryde, Emily A, Janzen, William P

“…The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in…”
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A Novel Antimicrobial and Fire Resistant Fabric by Frick, Lloyd, Ph.D, Boyd, Alan, R. Ph, Greenfield, Russell, MD

“…Silver salt crystals incorporated into polyester (PET) fibers confer durable antimicrobial activity that can permanently protect fabrics made with them. We…”
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The Persistence of Antimicrobial Effects in Fabrics and Garments Embedded with Silver after Home and Industrial Launderings by Boyd, Alan, RPh, MAc, Greenfield, Russell, MD, Frick, Lloyd, PhD

“…In healthcare facilities, soft surfaces such as curtains, sheets, pillowcases, blankets and upholstered furniture may harbor bacteria and other pathogens…”
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Inhibition of Colony-Stimulating-Factor-1 Signaling in vivo with the Orally Bioavailable cFMS Kinase Inhibitor GW2580 by James G. Conway, McDonald, Brad, Janet Parham, Barry Keith, David W. Rusnak, Eva Shaw, Jansen, Marilyn, Peiyuan Lin, Alan Payne, Renae M. Crosby, Jennifer H. Johnson, Lloyd Frick, Min-Hwa Jasmine Lin, Scott Depee, Sarva Tadepalli, Bart Votta, James, Ian, Karen Fuller, Timothy J. Chambers, Kull, Frederick C., Stanley D. Chamberlain, Hutchins, Jeff T., Schlessinger, Joseph

“…Colony-stimulating-factoM (CSF-1) signaling through cFMS receptor kinase is increased in several diseases. To help investigate the role of cFMS kinase in…”
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Enfuvirtide plasma levels and injection site reactions using a needle-free gas-powered injection system (Biojector) by HARRIS, Marianne, JOY, Ruth, LARSEN, Gerene, VALYI, Monica, WALKER, Ekaterina, FRICK, Lloyd W, PALMATIER, Robin M, WRING, Stephen A, MONTANER, Julio S. G

“…To assess the use of the Biojector B2000 needle-free gas-powered injection system for subcutaneous administration of enfuvirtide in HIV-infected patients and…”
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Substituted N-Phenylisothioureas:  Potent Inhibitors of Human Nitric Oxide Synthase with Neuronal Isoform Selectivity by Shearer, Barry G, Lee, Shuliang, Oplinger, Jeffrey A, Frick, Lloyd W, Garvey, Edward P, Furfine, Eric S

“…S-Ethyl N-phenylisothiourea (4) has been found to be a potent inhibitor of both the human constitutive and inducible isoforms of nitric oxide synthase. A…”
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9-182 - A Novel Antimicrobial and Fire Resistant Fabric by Frick, Lloyd, Boyd, Alan, Greenfield, Russell

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Identification of the nucleotide binding site of HIV-1 reverse transcriptase using dTTP as a photoaffinity label by Cheng, Nancy, Merrill, Barbara M, Painter, George R, Frick, Lloyd W, Furman, Phillip A

“…We have utilized UV-induced cross-linking of [methyl-3H]dTTP to identify the nucleotide binding site on heterodimeric HIV-1 reverse transcriptase (RT). RT was…”
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Cassette dosing: rapid in vivo assessment of pharmacokinetics by Frick, Lloyd W, Adkison, Kimberly K, Wells-Knecht, Kevin J, Woollard, Patrick, Higton, David M

“…Cassette dosing, combining many test chemicals into one dose solution, is an attractive method for increasing the throughput of in vivo pharmacokinetic…”
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Novel 6-alkoxypurine 2',3'-dideoxynucleosides as inhibitors of the cytopathic effect of the human immunodeficiency virus by Burns, Charlene L, St. Clair, Marty H, Frick, Lloyd W, Spector, Thomas, Averett, Devron R, English, Michael L, Holmes, Timothy J, Krenitsky, Thomas A, Koszalka, George W

“…Twenty-one 6-alkoxypurine 2',3'-dideoxynucleosides were enzymatically synthesized with nucleoside phosphorylases purified from E. coli. Eighteen analogs…”
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Filtration Improves the Performance of a High-Throughput Screen for Anti-Mycobacterial Compounds: e96348 by Cheng, Nancy, Porter, Melissa A, Frick, Lloyd W, Nguyen, Yvonne, Hayden, Jennifer D, Young, Ellen F, Braunstein, Miriam S, Hull-Ryde, Emily A, Janzen, William P

“…The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in…”
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Lamivudine Therapy of WHV-Infected Woodchucks by Mason, William S., Cullen, John, Moraleda, Gloria, Saputelli, Jeffry, Aldrich, Carol E., Miller, Darren S., Tennant, Bud, Frick, Lloyd, Averett, Devron, Condreay, Lynn D., Jilbert, Allison R.

“…Hepatitis B viruses establish a chronic, productive, and noncytopathic infection of hepatocytes. Viral products are produced by transcription from multiple…”
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Synthesis of novel anilinoquinolines as c-fms inhibitors by Smalley, Terrence L., Chamberlain, Stanley D., Mills, Wendy Y., Musso, David L., Randhawa, Sab A., Ray, John A., Samano, Vicente, Frick, Lloyd

“…A novel series of potent substituted anilinoquinolines were discovered as c-fms inhibitors. The potency could be manipulated upon modification of the C4…”
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Development of novel benzimidazole riboside compounds for treatment of cytomegalovirus disease by Chulay, J, Biron, K, Wang, L, Underwood, M, Chamberlain, S, Frick, L, Good, S, Davis, M, Harvey, R, Townsend, L, Drach, J, Koszalka, G

“…Benzimidazole ribosides are a new class of compounds with novel mechanisms of action against CMV. One compound in this series, BDCRB, inhibits CMV DNA…”
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In vivo antiviral activity and pharmacokinetics of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in woodchuck hepatitis virus-infected woodchucks by CULLEN, J. M, SMITH, S. L, GOULDING, A, BIRON, K, DAVIS, M. G, DUNN, S. E, BOTTERON, C, CECCHI, A, LINSEY, D, LINZEY, D, FRICK, L, PAFF, M. T

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells by Frick, L W, Nelson, D J, St Clair, M H, Furman, P A, Krenitsky, T A

“…The effects of 3'-azido-3'-deoxythymidine (AZT) on the deoxynucleotide pools of three human cell lines, HL-60, H-9, and K-562, were determined. The…”
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electrophoretic investigation of the cytosolic di- and tripeptidases of fish: molecular weights, substrate specificities, and tissue and phylogenetic distributions by Frick, L

“…The cytosolic di- and tripeptidases of fish were studied in an electrophoretic phylogenetic survey that included elasmobranchs, a holostean, and teleosts…”
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Inhibition of dihydropyrimidine dehydrogenase by 5-propynyluracil, a metabolite of the anti-varicella zoster virus agent netivudine by Peck, R, Wiggs, R, Callaghan, J, Wootton, R, Crome, P, Fraser, I, Frick, L, Posner, J

“…To study the effects of the anti-herpetic drug netivudine on dihydropyrimidine dehydrogenase activity in elderly volunteers and to relate them to…”
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Transition-state stabilization by adenosine deaminase: structural studies of its inhibitory complex with deoxycoformycin by Frick, Lloyd, Wolfenden, Richard, Smal, Elma, Baker, David C

“…Experiments with radioactive deoxycoformycin indicate that the inhibitor is released from calf intestinal adenosine deaminase after the enzyme-inhibitor…”
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Synthesis and Evaluation of a Series of 2′-Deoxy Analogues of The Antiviral Agent 5,6-Dichloro-2-Isopropylamino-1-(β-L-Ribofuranosyl)-1H-Benzimidazole (1263W94) by Chan, Joseph H., Chamberlain, Stanley D., Biron, Karen K., Davis, Michelle G., Harvey, Robert J., Selleseth, Dean W., Dornsife, Ronna E., Dark, Ernest H., Frick, Lloyd W., Townsend, Leroy B., Drach, John C., Koszalka, George W.

“…A series of 2′-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(β-L-ribofuranosyl)-1H-benzimidazole (1263W94) were synthesized and…”
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