Search Results - "Freynhagen, R."

Response: letter: pure nociceptive pain is very rare by Freynhagen, R.

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Neuropathic pain in cancer: systematic review, performance of screening tools and analysis of symptom profiles by Mulvey, M.R., Boland, E.G., Bouhassira, D., Freynhagen, R., Hardy, J., Hjermstad, M.J., Mercadante, S., Pérez, C., Bennett, M.I.

“…The objectives of this study were to evaluate the methodological quality of rigorous neuropathic pain assessment tools in applicable clinical studies, and…”
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Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens by Freynhagen, Rainer, Strojek, Krzysztof, Griesing, Teresa, Whalen, Ed, Balkenohl, Michael

“…Pregabalin binds with high affinity to the alpha 2-delta subunit protein of voltage-gated calcium channels and, thereby, reduces release of excitatory…”
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Safety of tapentadol compared with other opioids in chronic pain treatment: network meta-analysis of randomized controlled and withdrawal trials by Freynhagen, R., Elling, C., Radic, T., Sohns, M., Liedgens, H., James, D., McCool, R., Edwards, M.

“…To assess the relative safety of oral tapentadol PR and other opioid analgesics for moderate or severe chronic pain in adults, we conducted a systematic review…”
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Neuropathic pain phenotyping as a predictor of treatment response in painful diabetic neuropathy: Data from the randomized, double-blind, COMBO-DN study by Bouhassira, Didier, Wilhelm, Stefan, Schacht, Alexander, Perrot, Serge, Kosek, Eva, Cruccu, Giorgio, Freynhagen, Rainer, Tesfaye, Solomon, Lledó, Alberto, Choy, Ernest, Marchettini, Paolo, Micó, Juan Antonio, Spaeth, Michael, Skljarevski, Vladimir, Tölle, Thomas

“…Duloxetine and pregabalin have different effects on neuropathic pain components. This might explain differential responses to these drugs when given either…”
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painPREDICT: first interim data from the development of a new patient-reported pain questionnaire to predict treatment response using sensory symptom profiles by Tölle, T. R., Baron, R., de Bock, E., Junor, R., Dias Barbosa, C., Marshall, S. F., Arnould, B., Freynhagen, R.

“…Objective: Sensory symptom patterns may be useful for predicting treatment response, and, thus, improve individual therapy in patients suffering from…”
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A cross-sectional survey of 3035 patients with fibromyalgia: subgroups of patients with typical comorbidities and sensory symptom profiles by Rehm, Stefanie E., Koroschetz, Jana, Gockel, Ulrich, Brosz, Mathias, Freynhagen, Rainer, Tölle, Thomas R., Baron, Ralf

“…Objectives. Patients with FM are heterogeneous. They present with a variety of pain qualities, sensory abnormalities and additional comorbidities. The aim was…”
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Treatment of painful radiculopathies with capsaicin 8% cutaneous patch by Baron, R., Treede, R.D., Birklein, F., Cegla, T., Freynhagen, R., Heskamp, M.L., Kern, K.U., Maier, C., Rolke, R., Seddigh, S., Sommer, C., Ständer, S., Maihöfner, C.

“…Background and objective: The treatment of neuropathic pain due to low-back (lumbosacral) radiculopathies, a common source of neuropathic pain, is challenging…”
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Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses by Kringel, D, Ultsch, A, Zimmermann, M, Jansen, J-P, Ilias, W, Freynhagen, R, Griessinger, N, Kopf, A, Stein, C, Doehring, A, Resch, E, Lötsch, J

“…Next-generation sequencing (NGS) provides unrestricted access to the genome, but it produces ‘big data’ exceeding in amount and complexity the classical…”
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A retrospective analysis of the long-term test-retest stability of pain descriptors of the painDETECT questionnaire by Keller, T., Freynhagen, R., Tölle, T.R., Liwowsky, I., Möller, P., Hüllemann, P., Gockel, U., Stemmler, E., Baron, R.

“…Objective: PainDETECT (PD-Q) is a patient reported screening questionnaire to identify patients with neuropathic pain based on questions regarding typically…”
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Are there different predictors of analgesic response between antidepressants and anticonvulsants in painful diabetic neuropathy? by Marchettini, P., Wilhelm, S., Petto, H., Tesfaye, S., Tölle, T., Bouhassira, D., Freynhagen, R., Cruccu, G., Lledó, A., Choy, E., Kosek, E., Micó, J.A., Späth, M., Skljarevski, V., Lenox-Smith, A., Perrot, S.

“…Background To investigate baseline demographics and disease characteristics as predictors of the analgesic effect of duloxetine and pregabalin on diabetic…”
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Mechanism- and experience-based strategies to optimize treatment response to the capsaicin 8% cutaneous patch in patients with localized neuropathic pain by Treede, R.-D., Wagner, T., Kern, K.-U., Husstedt, I.W., Arendt, G., Birklein, F., Cegla, T., Freynhagen, R., Gockel, H.-H., Heskamp, M.-L., Jager, H., Joppich, R., Maier, C., Leffler, A., Nagelein, H.-H., Rolke, R., Seddigh, S., Sommer, C., Stander, S., Wasner, G., Baron, R.

“…Abstract The capsaicin 8% cutaneous patch is an emergent new treatment option for patients with peripheral neuropathic pain. In randomized controlled clinical…”
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Nitric oxide and pro-inflammatory cytokines correlate with pain intensity in chronic pain patients by Koch, A, Zacharowski, K, Boehm, O, Stevens, M, Lipfert, P, von Giesen, H-J, Wolf, A, Freynhagen, R

“…Inflammatory cytokines as well as nitric oxide (NO) play a key role in the pathogenesis of persistent and exaggerated pain states. To document this, we…”
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18 NEW SCREENING TOOLS FOR NEUROPATHIC PAIN: ARE THEY USEFUL FOR DAILY CLINICAL ROUTINE? by Freynhagen, R.

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Diagnosis and management of neuropathic pain by Freynhagen, R, Bennett, M I

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Screening of neuropathic pain components in patients with chronic back pain associated with nerve root compression: a prospective observational pilot study (MIPORT) by Freynhagen, Rainer, Baron, Ralf, Tölle, Thomas, Stemmler, Edgar, Gockel, Ulrich, Stevens, Markus, Maier, Christoph

“…ABSTRACT Objective: Chronic back pain is characterized by a combination of neuropathic and nociceptive mechanisms of pain generation. The prevalence of the…”
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Opioids for chronic non-cancer pain by Freynhagen, Rainer, Geisslinger, Gerd, Schug, Stephan A

“…Results of a 2009 Cochrane review of 10 controlled trials that compared opioids (oral codeine, oxycodone, oxymorphone, morphine, and transdermal fentanyl) with…”
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Diagnosis and management of neuropathic pain by FREYNHAGEN, R, BENNETT, M. I

“…Neuropathic pain arises from damage, or pathological change, in the peripheral or central nervous system. It is usually a chronic condition that can be…”
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The pain assessment for lower back symptoms (PAL-S): Qualitative development and cognitive evaluation of a new patient reported outcome measure for the assessment of low back pain by McCarrier, K.P, Martin, M.L, Ramasamy, A, Quintanar-Solares, M, Bushnell, D.M, Liedgens, H, Blum, S.I, Argoff, C.E, Freynhagen, R, Wallace, M.S, Patrick, D.L

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The Pain Assessment For Lower Back Impacts (PAL-I): Qualitative Development And Cognitive Evaluation Of A New Patient Reported Outcome Measure For The Assessment Of Impacts Of Low Back Pain by Ramasamy, A, Blum, S.I, McCarrier, K.P, Quintanar-Solares, M, Bushnell, D.M, Liedgens, H, Martin, M.L, Argoff, C.E, Patrick, D.L, Wallace, M.S, Freynhagen, R

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