Search Results - "Freyberger, A"

Critical evaluation of human health risks due to hydraulic fracturing in natural gas and petroleum production by Wollin, Klaus-Michael, Damm, G., Foth, H., Freyberger, A., Gebel, T., Mangerich, A., Gundert-Remy, U., Partosch, F., Röhl, C., Schupp, T., Hengstler, Jan G.

“…The use of hydraulic fracturing (HF) to extract oil and natural gas has increased, along with intensive discussions on the associated risks to human health…”
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The EU chemicals strategy for sustainability: critical reflections on proposed regulatory changes for endocrine disruptors and mixture toxicity by Batke, M., Damm, G., Foth, H., Freyberger, A., Gebel, T., Gundert-Remy, U., Hengstler, J., Mangerich, A., Partosch, F., Röhl, C., Schupp, T., Wollin, K. M.

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New aspects in deriving health-based guidance values for bromate in swimming pool water by Röhl, C., Batke, M., Damm, G., Freyberger, A., Gebel, T., Gundert-Remy, U., Hengstler, J. G., Mangerich, A., Matthiessen, A., Partosch, F., Schupp, T., Wollin, K. M., Foth, H.

“…Bromate, classified as a EU CLP 1B carcinogen, is a typical by-product of the disinfection of drinking and swimming pool water. The aim of this study was (a)…”
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Evaluation of the rodent Hershberger bioassay on intact juvenile males—Testing of coded chemicals and supplementary biochemical investigations by Freyberger, A, Schladt, L

“…Abstract Under the auspices of the Organization for Economic Cooperation and Development (OECD) the Hershberger assay on juvenile intact male rats is being…”
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The use of metabolising systems for in vitro testing of endocrine disruptors by Jacobs, M N, Janssens, W, Bernauer, U, Brandon, E, Coecke, S, Combes, R, Edwards, P, Freidig, A, Freyberger, A, Kolanczyk, R, Mc Ardle, C, Mekenyan, O, Schmieder, P, Schrader, T, Takeyoshi, M, van der Burg, B

“…Legislation and prospective legislative proposals in for instance the USA, Europe, and Japan require, or may require that chemicals are tested for their…”
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Evaluation of the rodent Hershberger bioassay: Testing of coded chemicals and supplementary molecular-biological and biochemical investigations by Freyberger, A, Ellinger-Ziegelbauer, H, Krötlinger, F

“…Abstract Under the auspices of the Organization for Economic Cooperation and Development (OECD) the Hershberger assay is being validated as an in vivo screen…”
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Screening for (anti)androgenic properties using a standard operation protocol based on the human stably transfected androgen sensitive PALM cell line. First steps towards validation by Freyberger, A., Witters, H., Weimer, M., Lofink, W., Berckmans, P., Ahr, H.-J.

“…Despite more than a decade of research in the field of endocrine active compounds targeting the androgen receptor (AR), and although suitable cell lines can be…”
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The assessment of estrogenic or anti-estrogenic activity of chemicals by the human stably transfected estrogen sensitive MELN cell line: Results of test performance and transferability by Witters, H., Freyberger, A., Smits, K., Vangenechten, C., Lofink, W., Weimer, M., Bremer, S., Ahr, P.H.-J., Berckmans, P.

“…The need for development and validation of in vitro hormone receptor transactivation assays as important alternative tools to study interactions with sex…”
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A novel method for measuring aromatase activity in tissue samples by determining estradiol concentrations by Tinwell, H., Rascle, J. B., Colombel, S., Al Khansa, I., Freyberger, A., Bars, R.

“…ABSTRACT Increasing scrutiny of endocrine disrupters has led to changes to European pesticide and biocide legislation and to the introduction of the Endocrine…”
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Development and standardization of a simple binding assay for the detection of compounds with affinity for the androgen receptor by Freyberger, Alexius, Ahr, Hans-Jürgen

“…Concerns have been raised whether natural and man-made chemicals might have the potential of interfering with the endocrine system. Especially interactions…”
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Studies on the goitrogenic mechanism of action of N, N, N′, N′-tetramethylthiourea by Freyberger, Alexius, Ahr, Hans-Jürgen

“…N, N, N′, N′-Tetramethylthiourea (TMTU) is a rat goitrogen inducing thyroid hyperplasia, hypertrophy, and tumor formation. Little is known about the exact…”
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Feasibility and potential gains of enhancing the subacute rat study protocol (OECD test guideline no. 407) by additional parameters selected to determine endocrine modulation. A pre-validation study to determine endocrine-mediated effects of the antiandrogenic drug flutamide by ANDREWS, P, FREYBERGER, A, HARTMANN, E, EIBEN, R, LOOF, I, SCHMIDT, U, TEMEROWSKI, M, BECKA, M

“…Groups of five male and five female Wistar rats were treated by gavage with 0, 1, 10, and 100 mg flutamide/kg body weight for at least 28 days to investigate…”
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Erratum: Unique electron polarimeter analyzing power comparison and precision spin-based energy measurement [Phys. Rev. ST Accel. Beams 7 , 042802 (2004)] by Grames, J. M., Sinclair, C. K., Mitchell, J., Chudakov, E., Fenker, H., Freyberger, A., Higinbotham, D. W., Poelker, M., Steigerwald, M., Tiefenback, M., Cavata, C., Escoffier, S., Marie, F., Pussieux, T., Vernin, P., Danagoulian, S., Dharmawardane, V., Fatemi, R., Joo, K., Zeier, M., Gorbenko, V., Nasseripour, R., Raue, B., Suleiman, R., Zihlmann, B.

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YO!—a time-of-arrival receiver for removal of helicity-correlated beam effects by Musson, J., Allison, T., Freyberger, A., Kuhn, J., Quinn, B.

“…A parity violation experiment, G 0, at Jefferson Lab is sensitive to arrival time differences, at the target, of electron beams in the two helicity states…”
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Sensitive detection of the endocrine effects of the estrogen analogue ethinylestradiol using a modified enhanced subacute rat study protocol (OECD Test Guideline no. 407) by ANDREWS, Peter, FREYBERGER, Alexius, HARTMANN, Elke, EIBEN, Rolf, LOOF, Ingo, SCHMIDT, Ulrich, TEMEROWSKI, Michael, FOLKERTS, Andree, STAHL, Bernhard, KAYSER, Martin

“…Groups of five male and female Wistar rats were treated by gavage with 0, 0.01, 0.05 or 0.2 mg/kg body weight of the known synthetic estrogen ethinylestradiol…”
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Unique electron polarimeter analyzing power comparison and precision spin-based energy measurement by Grames, J. M., Sinclair, C. K., Mitchell, J., Chudakov, E., Fenker, H., Freyberger, A., Higinbotham, D. W., Poelker, M., Steigerwald, M., Tiefenback, M., Cavata, C., Escoffier, S., Marie, F., Pussieux, T., Vernin, P., Danagoulian, S., Dharmawardane, V., Fatemi, R., Joo, K., Zeier, M., Gorbenko, V., Nasseripour, R., Raue, B., Suleiman, R., Zihlmann, B.

“…Precision measurements of the relative analyzing powers of five electron beam polarimeters, based on Compton, Møller, and Mott scattering, have been performed…”
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O-Phenylphenol and its Sodium and Potassium Salts: A Toxicological Assessment by Bomhard, E.M., Brendler-Schwaab, S.Y., Freyberger, A., Herbold, B.A., Leser, K.H., Richter, M.

“…Ortho-phenylphenol (OPP) and its sodium (SOPP) and potassium (POPP) salts are used as fungicides and disinfectants. Due to the widespread use of especially OPP…”
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Simple, rapid assays for conventional definite testing of endocrine disruptor hazard: Summary and recommendations by Fukushima, S., Freyberger, A.

“…Study protocols for the characterization of endocrine active compounds presented in Workshop 4 included the enhanced Organization for Economic Cooperation and…”
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Rapid, high performance liquid chromatography-based, periodate-coupled thiobarbituric acid method for the determination of sialic acid in bronchoalveolar lavage fluid by Freyberger, A

“…A simple, rapid high performance liquid chromatographic adaptation of the periodate-coupled thiobarbituric acid (TBA) method was developed for the…”
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Cardiovascular protection by combination of the selective nonsteroidal MR antagonist finerenone and the SGLT2 inhibitor empagliflozin in a preclinical model of hypertension-induced end-organ damage by Kolkhof, P, Hartmann, E, Freyberger, A, Pavkovic, M, Mathar, I, Sandner, P, Droebner, K, Joseph, A, Eitner, F, Hueser, J

“…Abstract Background The nonsteroidal mineralocorticoid receptor (MR) antagonist finerenone and SGLT2 inhibitors have demonstrated clinical benefits in HFrEF…”
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