Search Results - "Freund, Jenna"
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Bitter taste receptors stimulate phagocytosis in human macrophages through calcium, nitric oxide, and cyclic-GMP signaling
Published in Cellular and molecular life sciences : CMLS (01-01-2021)“…Bitter taste receptors (T2Rs) are GPCRs involved in detection of bitter compounds by type 2 taste cells of the tongue, but are also expressed in other tissues…”
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Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling
Published in The Journal of biological chemistry (22-06-2018)“…Bitter taste receptors (taste family 2 bitter receptor proteins; T2Rs), discovered in many tissues outside the tongue, have recently become potential…”
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Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor
Published in The Journal of biological chemistry (19-05-2017)“…Chronic rhinosinusitis has a significant impact on patient quality of life, creates billions of dollars of annual healthcare costs, and accounts for ∼20% of…”
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Polarization of protease-activated receptor 2 (PAR-2) signaling is altered during airway epithelial remodeling and deciliation
Published in The Journal of biological chemistry (08-05-2020)“…Protease-activated receptor 2 (PAR-2) is activated by secreted proteases from immune cells or fungi. PAR-2 is normally expressed basolaterally in…”
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The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning
Published in PLoS genetics (01-07-2021)“…The assembly of neuronal circuits involves the migrations of neurons from their place of birth to their final location in the nervous system, as well as the…”
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Protease‐activated receptor 2 activates airway apical membrane chloride permeability and increases ciliary beating
Published in The FASEB journal (01-01-2018)“…Mucociliary clearance, driven by the engine of ciliary beating, is the primary physical airway defense against inhaled pathogens and irritants. A better…”
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Taste receptors in the upper airway
Published in World Journal of Otorhinolaryngology-Head and Neck Surgery (01-03-2018)“…Taste receptors were named for their originally‐identified expression on the tongue and role in the sensation of taste (gustation). They are now known to be…”
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