Search Results - "Fretter, Caroline"
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Copy-number-gain of telomerase reverse transcriptase (hTERT) is associated with an unfavorable prognosis in esophageal adenocarcinoma
Published in Scientific reports (17-10-2023)“…Esophageal adenocarcinoma exhibits one of the highest mortality rates among all cancer entities. Multimodal therapy strategies have improved patients’ survival…”
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Extent and clinical significance of the therapy-relevant tight junction protein Claudin 18.2 in pancreatic ductal adenocarcinoma - real-world evidence
Published in Translational oncology (01-09-2024)“…•Zolbetuximab, a novel targeted therapy under investigation, targets Claudin 18.2.•We investigated the occurrence of Claudin 18.2 positivity in a real-world…”
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3
Co-expression patterns of cancer associated fibroblast markers reveal distinct subgroups related to patient survival in oropharyngeal squamous cell carcinoma
Published in Frontiers in cell and developmental biology (2024)“…The incidence of oropharyngeal squamous cell carcinoma (OPSCC) is rapidly increasing in high income countries due to its association with persistent high-risk…”
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Role of preexisting right ventricular remodeling in symptoms and prognosis after transcatheter tricuspid valve repair
Published in Clinical research in cardiology (06-03-2024)“…Severe tricuspid regurgitation (TR) is associated with chronic volume overload and right ventricular remodeling (RVR). Transcatheter tricuspid valve repair…”
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Hexokinase 2 as an independent risk factor for worse patient survival in esophageal adenocarcinoma and as a potential therapeutic target protein: A retrospective, single‑center cohort study
Published in Oncology letters (01-10-2024)“…Cancer cells exhibit a distinct metabolic profile that features an upregulation of less efficient glycolysis accompanied by lactate production for energy…”
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Upregulation of the histone γ-H2AX correlates with worse patient survival and basal-like subtype in pancreatic ductal adenocarcinoma
Published in Journal of cancer research and clinical oncology (19-03-2024)“…Purpose Patients with pancreatic ductal adenocarcinoma (PDAC) have yet to experience significant benefits from targeted therapy. Olaparib is currently the only…”
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Therapy-relevant MDM2 amplification in cholangiocarcinomas in Caucasian patients
Published in Therapeutic advances in medical oncology (01-01-2024)“…Cholangiocarcinomas (CCA) are a group of aggressive malignancies with poor prognosis. The distinct subtypes are related to different etiologies and genetic…”
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Therapy-relevant amplification in cholangiocarcinomas in Caucasian patients
Published in Therapeutic advances in medical oncology (01-11-2024)“…Background: Cholangiocarcinomas (CCA) are a group of aggressive malignancies with poor prognosis. The distinct subtypes are related to different etiologies and…”
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