Search Results - "Freshwater, T"

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  1. 1

    Model‐Based Characterization of the Pharmacokinetics of Pembrolizumab: A Humanized Anti–PD‐1 Monoclonal Antibody in Advanced Solid Tumors by Ahamadi, M, Freshwater, T, Prohn, M, Li, CH, de Alwis, DP, de Greef, R, Elassaiss‐Schaap, J, Kondic, A, Stone, JA

    “…Pembrolizumab, a potent antibody against programmed death 1 (PD‐1) receptor, has shown robust antitumor activity and manageable safety in patients with…”
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  2. 2

    Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer by Chatterjee, M., Turner, D.C., Felip, E., Lena, H., Cappuzzo, F., Horn, L., Garon, E.B., Hui, R., Arkenau, H.-T., Gubens, M.A., Hellmann, M.D., Dong, D., Li, C., Mayawala, K., Freshwater, T., Ahamadi, M., Stone, J., Lubiniecki, G.M., Zhang, J., Im, E., De Alwis, D.P., Kondic, A.G., Fløtten, Ø.

    Published in Annals of oncology (01-07-2016)
    “…In the phase I KEYNOTE-001 study, pembrolizumab demonstrated durable antitumor activity in patients with advanced non-small-cell lung cancer (NSCLC). We sought…”
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  3. 3

    Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Size Dynamics in Pembrolizumab‐Treated Advanced Melanoma by Chatterjee, MS, Elassaiss‐Schaap, J, Lindauer, A, Turner, DC, Sostelly, A, Freshwater, T, Mayawala, K, Ahamadi, M, Stone, JA, Greef, R, Kondic, AG, Alwis, DP

    “…Pembrolizumab is a potent immune‐modulating antibody active in advanced melanoma, as demonstrated in the KEYNOTE‐001, ‐002, and ‐006 studies. Longitudinal…”
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    Application of the Isolated Perfused Rat Kidney Model to Assess Gender Effects on Drug Excretion by Taft, D. R., Dontabhaktuni, A., Babayeva, M., Nakatani-Freshwater, T., Savant, I. A.

    Published in Drug development and industrial pharmacy (01-09-2006)
    “…ABSTRACTPurpose. To study the effect of gender on the renal disposition of two organic anions, p-aminohippuric acid (PAH) and furosemide (FSM) in the isolated…”
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    When doctors might kill their patients by Twycross, Robert, Morris, Christopher R., Freshwater, G. T., McKay, A. C.

    Published in BMJ (04-09-1999)
    “…[...]although it may occasionally be necessary (and acceptable) to render a patient unconscious, it remains unacceptable (and unnecessary) to cause death…”
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    Determination of soil water phosphorus with a new nylon suction cup by Tischner, T. (Institute of Freshwater Ecology and Inland Fisheries, Berlin, Germany.), Nutzmann, G, Pothig, R

    “…A new nylon suction cup is presented with low adsorption capacity, thus making it suitable for the determination of a variety of trace elements in soils. The…”
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