Search Results - "Freshwater, T"
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Model‐Based Characterization of the Pharmacokinetics of Pembrolizumab: A Humanized Anti–PD‐1 Monoclonal Antibody in Advanced Solid Tumors
Published in CPT: pharmacometrics and systems pharmacology (01-01-2017)“…Pembrolizumab, a potent antibody against programmed death 1 (PD‐1) receptor, has shown robust antitumor activity and manageable safety in patients with…”
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Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer
Published in Annals of oncology (01-07-2016)“…In the phase I KEYNOTE-001 study, pembrolizumab demonstrated durable antitumor activity in patients with advanced non-small-cell lung cancer (NSCLC). We sought…”
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Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Size Dynamics in Pembrolizumab‐Treated Advanced Melanoma
Published in CPT: pharmacometrics and systems pharmacology (01-01-2017)“…Pembrolizumab is a potent immune‐modulating antibody active in advanced melanoma, as demonstrated in the KEYNOTE‐001, ‐002, and ‐006 studies. Longitudinal…”
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Being over 75 isn’t the end of life
Published in BMJ (Online) (04-04-2019)Get full text
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3344 Relationship between pembrolizumab exposure and efficacy/safety in 1016 patients (pts) with advanced or metastatic melanoma
Published in European journal of cancer (1990) (01-09-2015)Get full text
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Application of the Isolated Perfused Rat Kidney Model to Assess Gender Effects on Drug Excretion
Published in Drug development and industrial pharmacy (01-09-2006)“…ABSTRACTPurpose. To study the effect of gender on the renal disposition of two organic anions, p-aminohippuric acid (PAH) and furosemide (FSM) in the isolated…”
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Physician associates should not be regulated by the General Medical Council, and doctors should tell it so
Published in BMJ (Online) (24-05-2024)Get more information
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When doctors might kill their patients. Patients must never be left to suffer so that doctors "stay out of trouble"
Published in BMJ (Online) (04-09-1999)Get full text
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When doctors might kill their patients
Published in BMJ (04-09-1999)“…[...]although it may occasionally be necessary (and acceptable) to render a patient unconscious, it remains unacceptable (and unnecessary) to cause death…”
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Determination of soil water phosphorus with a new nylon suction cup
Published in Bulletin of environmental contamination and toxicology (01-09-1998)“…A new nylon suction cup is presented with low adsorption capacity, thus making it suitable for the determination of a variety of trace elements in soils. The…”
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