Search Results - "Frerich, Candace"

Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma by Brayer, Kathryn J, Frerich, Candace A, Kang, Huining, Ness, Scott A

“…Adenoid cystic carcinoma (ACC), the second most common malignancy of salivary glands, is a rare tumor with a bleak prognosis for which therapeutic targets are…”
Get more information

Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes by Frerich, Candace A, Brayer, Kathryn J, Painter, Brandon M, Kang, Huining, Mitani, Yoshitsugu, El-Naggar, Adel K, Ness, Scott A

“…The relative rarity of salivary gland adenoid cystic carcinoma (ACC) and its slow growing yet aggressive nature has complicated the development of molecular…”
Get full text

Abstract 1990: Unique in vitro transcriptional activities of oncogenic Myb fusions identified in salivary gland adenoid cystic carcinoma by Frerich, Candace A., Ness, Scott A.

“…Abstract Chromosomal translocations involving the MYB and NFIB (t(6;9)) genes are the sole recurrent cytogenetic aberration in Adenoid Cystic Carcinoma (ACC),…”
Get full text

N-Terminal Truncated Myb with New Transcriptional Activity Produced Through Use of an Alternative MYB Promoter in Salivary Gland Adenoid Cystic Carcinoma by Frerich, Candace A, Sedam, Hailey N, Kang, Huining, Mitani, Yoshitsugu, El-Naggar, Adel K, Ness, Scott A

“…Adenoid cystic carcinoma (ACC) is an aggressive salivary gland tumor that frequently displays perineural invasion and is often associated with translocations…”
Get full text

Abstract P5-04-02: Modulation of glucocorticoid receptor activity in invasive lobular carcinoma progression by Frerich, Candace, Durdana, Ishrat, Chatterjee, Sumanta, Hanker, Ariella, Bennett, Lynda, Arteaga, Carlos L., Conzen, Suzanne D.

“…Abstract While considered a relatively uncommon breast cancer (BC) subtype, there are an estimated 39,000 new invasive lobular carcinoma (ILC) cases in the US…”
Get full text

Abstract 1507: Multiple mechanisms of Myb gene activation revealed through transcriptome analysis of salivary gland adenoid cystic carcinoma by Frerich, Candace, Brayer, Kathryn, Painter, Brandon, Ness, Scott

“…Abstract Adenoid cystic carcinoma (ACC) of the salivary gland is a rare head and neck malignancy with poor long-term prognosis. Hallmark chromosomal…”
Get full text

Abstract PO4-28-09: Upregulation of the immune checkpoint protein B7-H3 is associated with an immune suppressive microenvironment in progression from in situ to invasive lobular breast cancer by Bennett, Lynda, Sahoo, Sunati, Lewis, Cheryl, Raman, Indu, Frerich, Candace, Chen, Guanchun, Xu, Min, Conzen, Suzanne

“…Abstract Invasive lobular breast cancer (ILC) is an understudied subtype of breast cancer characterized by late recurrence, metastasis to serosal surfaces…”
Get full text

Abstract PO2-27-08: Discovery of glucocorticoid receptor-induced EMT and integrin gene expression and increased cell motility in invasive lobular breast cancer by Porter, Baylee, Frerich, Candace, Laine, Muriel, Sahoo, Sunati, Greene, Geoffrey, Lee, Jeon, Bennett, Lynda, Conzen, Suzanne

“…Abstract Estrogen receptor (ER)-positive, invasive lobular carcinoma (ILC) is the second most common histological subtype of breast cancer. Although the…”
Get full text

Clonally related benign cephalic histiocytosis, histiocytic sarcoma, and T-cell acute lymphoblastic leukemia: Expanding the spectrum of histiocytic transdifferentiation by Thellman, J Connor, Fang, Milie M, Neff, Tanaya, Thomas, George, Frerich, Candace, Press, Richard, Dhossche, Julie M, White, Kevin P, Chang, Bill H, Raess, Philipp W

Get full text

Mechanisms and Consequences of Myb Gene Activation in Salivary Gland Tumors by Frerich, Candace

“…Salivary gland adenoid cystic carcinoma (ACC) is an aggressive tumor with a tendency to infiltrate surrounding nerves and metastasize to distant sites. The…”
Get full text

Abstract 5283: Glucocorticoid receptor (GR) activity alters invasive lobular breast cancer (ILC) oncogenic properties by Durdana, Ishrat, Frerich, Candace, Laine, Muriel, Rindhe, Smita, Bennett, Lynda, Bachoo, Robert, Greene, Geoffrey, Conzen, Suzanne

“…Abstract Invasive breast cancer (BC) is commonly divided into two subtypes, invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC). ILC makes up…”
Get full text

Abstract P2-20-01: Patient-derived triple-negative breast cancer organoids as a platform for glucocorticoid receptor- mediated mechanisms of immunotherapy response and resistance by Shiang, Christine, Frerich, Candace, Durdana, Ishrat, Lewis, Cheryl, Bennett, Lynda B., Arteaga, Carlos, Conzen, Suzanne D.

“…Abstract Background: In early-stage triple-negative breast cancer (TNBC), high glucocorticoid receptor (GR) expression correlates with worse relapse-free…”
Get full text

Abstract 2699: Glucocorticoid receptor biology in lobular breast cancer by Frerich, Candace, Durdana, Ishrat, Hanker, Ariella, Arteaga, Carlos L., Bennett, Lynda, Conzen, Suzanne

“…Abstract While considered uncommon, there are an estimated 39,000 new invasive lobular carcinoma (ILC) cases in the US yearly, making it the sixth most common…”
Get full text

Abstract 2360: Digital spatial profiling of RNA and protein in the tumor microenvironment of invasive lobular breast cancer by Bennett, Lynda B., Sahoo, Sunati, Lewis, Cheryl M., Raman, Indu, Frerich, Candace, Chen, Guanchun, Xu, Min, Conzen, Suzanne D.

“…Abstract Invasive lobular breast cancer (ILC) is an understudied breast cancer subtype with late recurrence, metastasis to serosal surfaces including the…”
Get full text

Abstract P2-21-08: Digital spatial profiling of RNA and protein in the invasive lobular breast cancer microenvironment by Bennett, Lynda B., Frerich, Candace, Sahoo, Sunati, Lewis, Cheryl, Raman, Indu, Xu, Min, Chen, Guanchun, Conzen, Suzanne D.

“…Abstract Invasive lobular breast cancer (ILC) is an understudied subtype of breast cancer with late recurrence, metastasis to serosal surfaces, such as the…”
Get full text

Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases by Porter, Baylee A, Frerich, Candace, Lainé, Muriel, Clark, Abigail B, Durdana, Ishrat, Lee, Jeon, Taya, Manisha, Sahoo, Sunati, Greene, Geoffrey L, Bennett, Lynda, Conzen, Suzanne D

“…Estrogen receptor-positive (ER+) invasive lobular breast cancer (ILC) comprises about ~15% of breast cancer. ILC's unique genotypic (loss of wild type…”
Get full text

Investigation of hAT and piggyBac transposons in mouse-eared bats (Genus: Myotis) by Frerich, Candace, Ammerman, Loren

“…Transposable elements, mobile DNA sequences present in virtually all organisms, have previously been thought to be inactive in mammals. However, current…”
Get full text