Search Results - "Frenz, Silke"

All-trans retinoic acid works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells by García-Guerrero, Estefanía, Rodríguez-Lobato, Luis G, Sierro-Martínez, Belén, Danhof, Sophia, Bates, Stephan, Frenz, Silke, Haertle, Larissa, Götz, Ralph, Sauer, Markus, Rasche, Leo, Kortüm, K Martin, Pérez-Simón, Jose A, Einsele, Hermann, Hudecek, Michael, Prommersberger, Sabrina R

“…B-cell maturation antigen (BCMA) is the lead antigen for chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma (MM). A challenge is inter- and…”
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Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia by Jetani, Hardikkumar, Navarro-Bailón, Almudena, Maucher, Marius, Frenz, Silke, Verbruggen, Christina, Yeguas, Ana, Vidriales, María Belén, González, Marcos, Rial Saborido, Judit, Kraus, Sabrina, Mestermann, Katrin, Thomas, Simone, Bonig, Halvard, Luu, Maik, Monjezi, Razieh, Mougiakakos, Dimitrios, Sauer, Markus, Einsele, Hermann, Hudecek, Michael

“…Acute myeloid leukemia (AML) is an attractive entity for the development of chimeric antigen receptor (CAR) T-cell immunotherapy because AML blasts are…”
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A Novel Pharmacologic ‘Remote Control’ to Steer CAR-T Cell Function In Vivo by Mestermann, Katrin, Rydzek, Julian, Silke, Frenz, Nerreter, Thomas, Andreas, Mades, Einsele, Hermann, Hudecek, Michael

“…▪ Background: Immunotherapy with chimeric antigen receptor T cells (CAR-T) is emerging as a transformative novel treatment for hematologic malignancies. In…”
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Mutation of the TBCE gene causes disturbance of microtubules in the auditory nerve and cochlear outer hair cell degeneration accompanied by progressive hearing loss in the pmn/pmn mouse by Rak, Kristen, Frenz, Silke, Radeloff, Andreas, Groh, Janos, Jablonka, Sibylle, Martini, Rudolf, Hagen, Rudolf, Mlynski, Robert

“…The progressive motor neuronopathy (pmn/pmn) mouse, an animal model for a fast developing human motor neuron disorder, is additionally characterized by…”
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Dynamic changes of the neurogenic potential in the rat cochlear nucleus during post-natal development by Rak, Kristen, Völker, Johannes, Frenz, Silke, Scherzed, Agmal, Radeloff, Andreas, Hagen, Rudolf, Mlynski, Robert

“…Neuronal stem cells have been described in the post-natal cochlear nucleus recently. The aim of the study was to analyse the neurogenic potential in the…”
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Effects of the neurotrophic factors BDNF, NT-3, and FGF2 on dissociated neurons of the cochlear nucleus by Rak, Kristen, Völker, Johannes, Frenz, Silke, Scherzad, Agmal, Schendzielorz, Philipp, Radeloff, Andreas, Jablonka, Sibylle, Hagen, Rudolf, Mlynski, Robert

“…The cochlear nucleus is the first relay station for acoustic information in the auditory pathway and its cellular integrity is affected by hearing loss…”
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ATRA works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T-cells by García-Guerrero, Estefanía, Rodríguez-Lobato, Luis G, Sierro-Martínez, Belén, Danhof, Sophia, Bates, Stephan, Frenz, Silke, Haertle, Larissa, Götz, Ralph, Sauer, Markus, Rasche, Leo, Kortüm, K Martin, Pérez-Simón, Jose A, Einsele, Hermann, Hudecek, Michael, Prommersberger, Sabrina R

“…B-cell maturation antigen (BCMA) is the lead antigen for CAR T-cell therapy in multiple myeloma (MM). A challenge is inter- and intra-patient heterogeneity in…”
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Cochlear nucleus whole mount explants promote the differentiation of neuronal stem cells from the cochlear nucleus in co-culture experiments by Rak, Kristen, Völker, Johannes, Jürgens, Lukas, Völker, Christine, Frenz, Silke, Scherzad, Agmal, Schendzielorz, Philipp, Jablonka, Sibylle, Mlynski, Robert, Radeloff, Andreas, Hagen, Rudolf

“…Abstract The cochlear nucleus is the first brainstem nucleus to receive sensory input from the cochlea. Depriving this nucleus of auditory input leads to…”
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Mosaic pattern of Cre recombinase expression in cochlear outer hair cells of the Brn3.1 Cre mouse by Frenz, Silke, Rak, Kristen, Völker, Johannes, Jürgens, Lukas, Scherzad, Agmal, Schendzielorz, Philipp, Radeloff, Andreas, Jablonka, Sibylle, Hansen, Stefan, Mlynski, Robert, Hagen, Rudolf

“…The Brn3.1 gene encodes for the protein Brn3.1, which is a member of the POU-IV class of transcription factors. Mutation leads to nonsyndromic human…”
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