Search Results - "Frenken, Leon"

Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection by Tokuhara, Daisuke, Álvarez, Beatriz, Mejima, Mio, Hiroiwa, Tomoko, Takahashi, Yuko, Kurokawa, Shiho, Kuroda, Masaharu, Oyama, Masaaki, Kozuka-Hata, Hiroko, Nochi, Tomonori, Sagara, Hiroshi, Aladin, Farah, Marcotte, Harold, Frenken, Leon G J, Iturriza-Gómara, Miren, Kiyono, Hiroshi, Hammarström, Lennart, Yuki, Yoshikazu

“…Rotavirus-induced diarrhea is a life-threatening disease in immunocompromised individuals and in children in developing countries. We have developed a system…”
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Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial by Smuts, Cornelius M, Matsungo, Tonderayi M, Malan, Linda, Kruger, Herculina S, Rothman, Marinel, Kvalsvig, Jane D, Covic, Namukolo, Joosten, Karen, Osendarp, Saskia J M, Bruins, Maaike J, Frenken, Leon G J, Lombard, Carl J, Faber, Mieke

“…Evidence on the effect of small-quantity lipid-based nutrient supplements (SQ-LNSs) on early child growth and development is mixed. This study assessed the…”
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In vitro neutralisation of rotavirus infection by two broadly specific recombinant monovalent llama-derived antibody fragments by Aladin, Farah, Einerhand, Alexandra W C, Bouma, Janneke, Bezemer, Sandra, Hermans, Pim, Wolvers, Danielle, Bellamy, Kate, Frenken, Leon G J, Gray, Jim, Iturriza-Gómara, Miren

“…Rotavirus is the main cause of viral gastroenteritis in young children. Therefore, the development of inexpensive antiviral products for the prevention and/or…”
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Anti-Rotavirus Protein Reduces Stool Output in Infants With Diarrhea: A Randomized Placebo-Controlled Trial by Sarker, Shafiqul A, Jäkel, Martin, Sultana, Shamima, Alam, Nur H, Bardhan, Pradip K, Chisti, Mohammod J, Salam, Mohammed A, Theis, Winfried, Hammarström, Lennart, Frenken, Leon G.J

“…Background & Aims Rotavirus infection is a leading cause of morbidity and mortality in children younger than 5 years of age. Current treatment options are…”
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Inhibition of iron absorption by calcium is modest in an iron-fortified, casein- and whey-based drink in Indian children and is easily compensated for by addition of ascorbic acid by Walczyk, Thomas, Muthayya, Sumithra, Wegmüller, Rita, Thankachan, Prashanth, Sierksma, Aafje, Frenken, Leon G J, Thomas, Tinku, Kurpad, Anura, Hurrell, Richard F

“…Calcium inhibits and ascorbic acid (AA) enhances iron absorption from iron-fortified foods. Absorption efficiency depends on iron status, although the…”
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The role of urine sodium in acutely decompensated heart failure by Hoen, Mick, Hofman, Delian E, Hompes, Bjorn H.A., Peeters, Lukas E.E., Langenveld, Bart, van Kimmenade, Roland R.J., Frenken, Leon A.M., Lenderink, Timo, Brunner-La Rocca, Hans-Peter, Sanders-Van Wijk, Sandra

“…Diuretic resistance is common and results in poor outcome. Spot urine sodium (UrNa) is suggested as a tool to tailor diuretics and improve efficacy of therapy…”
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The spectrum of thrombotic microangiopathy related to monoclonal gammopathy by van Doorn, Daan P C, Abdul-Hamid, Myrurgia A, Frenken, Leon A M, van Paassen, Pieter, Timmermans, Sjoerd A M E G

“…Background Recent studies showed a high prevalence of monoclonal gammopathy (MG) in patients with thrombotic microangiopathy (TMA) aged over 50 years and…”
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Anti–Phospholipase A2 Receptor Antibodies and Malignancy in Membranous Nephropathy by Timmermans, Sjoerd A.M.E.G., BSc, Ayalon, Rivka, MD, van Paassen, Pieter, MD, PhD, Beck, Laurence H., MD, PhD, van Rie, Henk, Wirtz, Joris J.J.M., MD, PhD, Verseput, Gaico H., MD, PhD, Frenken, Leon A., MD, PhD, Salant, David J., MD, Cohen Tervaert, Jan Willem, MD, PhD

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Primary Podocytopathies After COVID-19 Vaccination by Timmermans, Sjoerd A.M.E.G., Busch, Matthias H., Abdul-Hamid, Myrurgia A., Frenken, Leon A.M., Aarnoudse, Albert-Jan, van Paassen, Pieter

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Therapeutic effect of llama derived VHH fragments against Streptococcus mutans on the development of dental caries by Krüger, Carina, Hultberg, Anna, Marcotte, Harold, Hermans, Pim, Bezemer, Sandra, Frenken, Leon G. J, Hammarström, Lennart

“…Streptococcus mutans is the main cause of dental caries. We evaluated the therapeutic effect of variable regions of a llama heavy chain antibody fragments…”
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Random serial sampling to evaluate efficacy of iron fortification: a randomized controlled trial of margarine fortification with ferric pyrophosphate or sodium iron edetate by Andersson, Maria, Theis, Winfried, Zimmermann, Michael B, Foman, Jasmin Tajeri, Jäkel, Martin, Duchateau, Guus SMJE, Frenken, Leon GJ, Hurrell, Richard F

“…BACKGROUND: Random serial sampling is widely used in population pharmacokinetic studies and may have advantages compared with conventional fixed time-point…”
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Insight Into Advance Care Planning for Patients on Dialysis by Janssen, Daisy J.A., MD, PhD, Spruit, Martijn A., PhD, Schols, Jos M.G.A., MD, PhD, van der Sande, Frank M., MD, PhD, Frenken, Leon A., MD, PhD, Wouters, Emiel F.M., MD, PhD

“…Abstract Context Advance care planning is not included in regular clinical care for patients on dialysis. Insight into life-sustaining treatment preferences…”
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Single-domain antibody fragments with high conformational stability by Dumoulin, Mireille, Conrath, Katja, Van Meirhaeghe, Annemie, Meersman, Filip, Heremans, Karel, Frenken, Leon G J, Muyldermans, Serge, Wyns, Lode, Matagne, André

“…A variety of techniques, including high‐pressure unfolding monitored by Fourier transform infrared spectroscopy, fluorescence, circular dichroism, and surface…”
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Llama Antibodies against a Lactococcal Protein Located at the Tip of the Phage Tail Prevent Phage Infection by DE HAARD, Hans J. W, BEZEMER, Sandra, LEDEBOER, Aat M, MÜLLER, Wally H, BOENDER, Piet J, MOINEAU, Sylvain, COPPELMANS, Marie-Cecile, VERKLEIJ, Arie J, FRENKEN, Leon G. J, VERRIPS, C. Theo

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Lactobacilli Expressing Variable Domain of Llama Heavy-Chain Antibody Fragments (Lactobodies) Confer Protection against Rotavirus-Induced Diarrhea by Pant, Neha, Hultberg, Anna, Zhao, Yaofeng, Svensson, Lennart, Pan-Hammarström, Qiang, Johansen, Kari, Pouwels, Peter H., Ruggeri, Franco M., Hermans, Pim, Frenken, Leon, Borén, Thomas, Marcotte, Harold, Hammarström, Lennart

“…BackgroundRotavirus-induced diarrhea poses a worldwide medical problem in causing substantial morbidity and mortality among children in developing countries…”
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Camelid Heavy-Chain Variable Domains Provide Efficient Combining Sites to Haptens by Spinelli, Silvia, Frenken, Leon G. J, Hermans, Pim, Verrips, Theo, Brown, Kieron, Tegoni, Mariella, Cambillau, Christian

“…Camelids can produce antibodies devoid of light chains and CH1 domains (Hamers-Casterman, C. et al. (1993) Nature 363, 446−448). Camelid heavy-chain variable…”
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Isolation of Llama Antibody Fragments for Prevention of Dandruff by Phage Display in Shampoo by Dolk, Edward, van der Vaart, Marcel, Lutje Hulsik, David, Vriend, Gert, de Haard, Hans, Spinelli, Silvia, Cambillau, Christian, Frenken, Leon, Verrips, Theo

“…As part of research exploring the feasibility of using antibody fragments to inhibit the growth of organisms implicated in dandruff, we isolated antibody…”
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Induced refolding of a temperature denatured llama heavy-chain antibody fragment by its antigen by Dolk, Edward, van Vliet, Cees, Perez, Janice M.J., Vriend, Gert, Darbon, Hervé, Ferrat, Gilles, Cambillau, Christian, Frenken, Leon G.J., Verrips, Theo

“…In a previous study we have shown that llama VHH antibody fragments are able to bind their antigen after a heat shock of 90°C, in contrast to the murine…”
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Thermal Unfolding of a Llama Antibody Fragment:  A Two-State Reversible Process by Pérez, Janice M. J, Renisio, Jean G, Prompers, Jeanine J, van Platerink, Chris J, Cambillau, Christian, Darbon, Hervé, Frenken, Leon G. J

“…Camelids produce functional “heavy chain” antibodies which are devoid of light chains and CH1 domains [Hamers-Casterman, C., et al. (1993) Nature 363,…”
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Lateral recognition of a dye hapten by a llama VHH domain by Spinelli, Silvia, Tegoni, Mariella, Frenken, Leon, van Vliet, Cees, Cambillau, Christian

“…Camelids, camels and llamas, have a unique immune system able to produce heavy-chain only antibodies. Their VH domains (VHHs) are the smallest binding units…”
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