Search Results - "Frenkel, Shahar"
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Efficacy and safety of intravitreal methotrexate for vitreo‐retinal lymphoma – 20 years of experience
Published in British journal of haematology (01-07-2021)“…Summary Vitreo‐retinal lymphoma (VRL) is the most common intraocular lymphoma and is highly associated with central nervous system (CNS) lymphoma (CNSL), both…”
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The importance of cytokines analysis in the diagnosis of vitreoretinal lymphoma
Published in Acta ophthalmologica (Oxford, England) (01-09-2020)“…Purpose To evaluate the efficacy of the different diagnostic tests for vitreoretinal lymphoma (VRL). Methods A cohort of 150 patients with a presumed diagnosis…”
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Ophthalmology practice during the COVID-19 pandemic
Published in BMJ open ophthalmology (19-04-2020)“…ObjectiveTo present an established practice protocol for safe and effective hospital-setting ophthalmic practice during the coronavirus disease 2019 (COVID-19)…”
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Role of oncogenic viruses in the development ocular surface squamous neoplasia
Published in International ophthalmology (01-11-2021)“…Purpose The pathogenesis of ocular surface squamous neoplasia is not fully understood. Therefore, we evaluated the role of oncogenic viruses in the…”
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Infectious Knockdown of CREB and HIF-1 for the Treatment of Metastatic Uveal Melanoma
Published in Cancers (26-07-2019)“…Uveal melanoma (UM) is the most prevalent primary intraocular cancer in adults. Up to half the patients develop metastases that are currently incurable, and…”
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Irreversible electroporation of human primary uveal melanoma in enucleated eyes
Published in PloS one (05-09-2013)“…Uveal melanoma (UM) is the most common primary intraocular tumor in adults and is characterized by high rates of metastatic disease. Although brachytherapy is…”
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The Pediatric Choroidal and Ciliary Body Melanoma Study
Published in Ophthalmology (Rochester, Minn.) (01-04-2016)“…Purpose To collect comprehensive data on choroidal and ciliary body melanoma (CCBM) in children and to validate hypotheses regarding pediatric CCBM: children…”
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PI3K/Akt Pathway Mutations in Retinoblastoma
Published in Investigative ophthalmology & visual science (01-11-2009)“…Many malignancies are known to be associated with abnormal activation of the PI3K-AKT pathway. Recently, a somatic mutation in the AKT1 gene (E17K) was…”
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Choroidal Metastasis of Adenocarcinoma of the Lung Presenting as Pigmented Choroidal Tumor
Published in Case reports in ophthalmology (01-01-2012)“…Our case represents a unique occurrence of pigmented choroidal tumor that clinically appeared as choroidal melanoma and was treated accordingly. At the same…”
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Suppression of Microphthalmia Transcriptional Activity by Its Association with Protein Kinase C-interacting Protein 1 in Mast Cells
Published in The Journal of biological chemistry (26-11-1999)“…Microphthalmia ( mi ) is a transcription factor that plays a major role in the regulation of growth and function in mast cells and melanocytes. Association of…”
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Intraocular Lymphoma
Published in Ophthalmology (Rochester, Minn.) (01-06-2007)Get full text
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Gender differences in clinical presentation and prognosis of uveal melanoma
Published in Investigative ophthalmology & visual science (23-01-2013)“…We examined the clinical differences in manifestation and prognosis of uveal melanoma (UM) between men and women. We evaluated 723 UM patients (325 males) who…”
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Treatment of conjunctival palpebral lesions using ruthenium plaque brachytherapy "Sandwich Technique"
Published in Canadian journal of ophthalmology (03-08-2024)“…Treatment of palpebral conjunctival lesions is problematic due to late diagnosis, difficult surgical approach, and the need to preserve eyelid integrity. We…”
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The challenge in the diagnosis and management of vitreoretinal lymphoma
Published in Clinical & experimental ophthalmology (01-03-2023)Get full text
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Vitreoretinal lymphoma: Central nervous system lymphoma risk with unilateral or bilateral ocular tumour. A multicentre collaboration
Published in Eye (London) (01-01-2023)“…Objectives To investigate the risk of developing central nervous system (CNS) lymphoma in patients with vitreoretinal lymphoma (VRL) presenting with unilateral…”
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The impact of monocular vision on motor function and quality of life in survivors of retinoblastoma
Published in Pediatric blood & cancer (01-05-2019)“…Background Monocular vision has been found to have a negative effect on children's motion processing and motor functions. Yet, knowledge of motor function of…”
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Insulin-like growth factor-1 as a predictive biomarker for metastatic uveal melanoma in humans
Published in Investigative ophthalmology & visual science (17-01-2013)“…High expression levels of insulin-like growth factor-1 (IGF-1) receptor were associated with metastatic uveal melanoma (UM). The purpose of this study was to…”
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Real‐world experience with belantamab mafodotin therapy for relapsed/refractory multiple myeloma: A multicentre retrospective study
Published in British journal of haematology (01-01-2023)“…Summary Belantamab mafodotin, an immuno‐conjugate targeting B‐cell maturation antigen, showed single‐agent activity in phase 1 and 2 studies, and was recently…”
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Genotype-phenotype correlation in the presentation of retinoblastoma among 149 patients
Published in Experimental eye research (01-05-2016)“…In this work, we describe the association between a germline RB1 mutation and disease presentation characteristics of retinoblastoma. The study evaluates a…”
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