Search Results - "Frenis, Katie"
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Thiol-based redox-active proteins as cardioprotective therapeutic agents in cardiovascular diseases
Published in Basic research in cardiology (01-12-2021)“…Thiol-based redox compounds, namely thioredoxins (Trxs), glutaredoxins (Grxs) and peroxiredoxins (Prxs), stand as a pivotal group of proteins involved in…”
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Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Cardiovascular disease is a leading cause of death and reduced quality of life, proven by the latest data of the Global Burden of Disease Study, and is only…”
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Cerebral consequences of environmental noise exposure
Published in Environment international (01-07-2022)“…The importance of noise exposure as a major environmental determinant of public health is being increasingly recognized. While in recent years a large body…”
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Accelerated Aging and Age-Related Diseases (CVD and Neurological) Due to Air Pollution and Traffic Noise Exposure
Published in International journal of molecular sciences (28-02-2021)“…The World Health Organization estimates that only approximately 25% of diversity in longevity is explained by genetic factors, while the other 75% is largely…”
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Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation
Published in European heart journal (07-10-2018)“…Abstract Aims Aircraft noise causes endothelial dysfunction, oxidative stress, and inflammation. Transportation noise increases the incidence of coronary…”
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Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression
Published in Nature communications (05-03-2024)“…Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule…”
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Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects
Published in Basic research in cardiology (01-12-2021)“…Aircraft noise induces vascular and cerebral inflammation and oxidative stress causing hypertension and cardiovascular/cerebral dysfunction. With the present…”
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Exacerbation of adverse cardiovascular effects of aircraft noise in an animal model of arterial hypertension
Published in Redox biology (01-07-2020)“…Arterial hypertension is the most important risk factor for the development of cardiovascular disease. Recently, aircraft noise has been shown to be associated…”
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Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice
Published in Redox biology (01-10-2021)“…Epidemiological studies showed that traffic noise has a dose-dependent association with increased cardiovascular morbidity and mortality. Whether microvascular…”
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The AMP-Activated Protein Kinase Plays a Role in Antioxidant Defense and Regulation of Vascular Inflammation
Published in Antioxidants (16-06-2020)“…Cardiovascular diseases represent the leading cause of global deaths and life years spent with a severe disability. Endothelial dysfunction and vascular…”
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Physical Activity in Polluted Air-Net Benefit or Harm to Cardiovascular Health? A Comprehensive Review
Published in Antioxidants (08-11-2021)“…Both exposure to higher levels of polluted air and physical inactivity are crucial risk factors for the development and progression of major noncommunicable…”
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Health position paper and redox perspectives - Disease burden by transportation noise
Published in Redox biology (01-02-2024)“…Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization concluded that chronic exposure to road traffic noise is a risk…”
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Noise-Induced Vascular Dysfunction, Oxidative Stress, and Inflammation Are Improved by Pharmacological Modulation of the NRF2/HO-1 Axis
Published in Antioxidants (19-04-2021)“…Vascular oxidative stress, inflammation, and subsequent endothelial dysfunction are consequences of traditional cardiovascular risk factors, all of which…”
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Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation
Published in Frontiers in molecular biosciences (18-11-2021)“…Environmental exposures represent a significant health hazard, which cumulatively may be responsible for up to 2/3 of all chronic non-communicable disease and…”
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GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation
Published in Antioxidants (23-07-2021)“…Sepsis causes high mortality in the setting of septic shock. LEADER and other trials revealed cardioprotective and anti-inflammatory properties of…”
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Endothelial α1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction
Published in Basic research in cardiology (01-03-2019)“…Mice with a global deletion of α1AMPK are characterized by endothelial dysfunction and NADPH oxidase subunit 2 (NOX-2)-mediated vascular oxidative stress…”
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Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development
Published in Frontiers in molecular biosciences (31-01-2022)“…Transportation noise is recognized as an important cardiovascular risk factor. Key mechanisms are noise-triggered vascular inflammation and oxidative stress…”
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In vivo analysis of noise dependent activation of white blood cells and microvascular dysfunction in mice
Published in MethodsX (01-01-2021)“…This article contains supporting information on data collection for the research article entitled “Aircraft noise exposure drives the activation of white blood…”
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Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors
Published in Free radical biology & medicine (01-07-2022)“…Environmental risk factors, including noise, air pollution, chemical agents, ultraviolet radiation (UVR) and mental stress have a considerable impact on human…”
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Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2020)“…OBJECTIVE:Cardiovascular outcome trials demonstrated that GLP-1 (glucagon-like peptide-1) analogs including liraglutide reduce the risk of cardiovascular…”
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