Search Results - "French, E D"

Toluene-Induced Locomotor Activity is Blocked by 6-Hydroxydopamine Lesions of the Nucleus Accumbens and the mGluR2 3 Agonist LY379268 by RIEGEL, A. C, ALI, S. F, FRENCH, E. D

“…The abuse of volatile inhalants remains a prominent, yet poorly understood, form of substance abuse among youth. Nevertheless, the identification of a…”
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Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra by French, Edward D, Dillon, Kathryn, Wu, Xiaofang

“…EXTRACELLULAR recordings were used to determine the effects of cannabinoids on the activity of dopamine neurons within the ventral tegmental area (VTA) and…”
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Repeated Exposure to the Abused Inhalant Toluene Alters Levels of Neurotransmitters and Generates Peroxynitrite in Nigrostriatal and Mesolimbic Nuclei in Rat by RIEGEL, A C, ALI, S F, TORINESE, S, FRENCH, E D

“…: Toluene, a volatile hydrocarbon found in a variety of chemical compounds, is misused and abused by inhalation for its euphorigenic effects. Toluene's…”
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A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study by Yin, Ruoyuan, French, Edward D

“…Increased neurotransmission within the mesolimbic dopamine system is considered an essential component for the rewarding and dependence producing properties of…”
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Acute Toluene Induces Biphasic Changes in Rat Spontaneous Locomotor Activity Which Are Blocked by Remoxipride by Riegel, Arthur C, French, Edward D

“…The behavioral hyperactivity elicited by most drugs of abuse has been linked to changes in mesolimbic dopamine neurotransmission. However, the locomotor…”
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Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons: an electrophysiological and behavioral comparison to phencyclidine by French, E D, Ferkany, J, Abreu, M, Levenson, S

“…Electrophysiological and behavioral methods were used to evaluate and compare the effects of the competitive N-methyl-D-aspartate (NMDA) receptor blocker, NPC…”
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Phencyclidine and the midbrain dopamine system: electrophysiology and behavior by French, E D

“…Phencyclidine (PCP) and PCP-like drugs increased firing rates and the amount of burst activity of A10 dopamine neurons recorded extracellularly in anesthetized…”
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N-methyl-D-aspartic acid biphasically regulates the biochemical and electrophysiological response of A10 dopamine neurons in the ventral tegmental area: in vivo microdialysis and in vitro electrophysiological studies by Wang, T, O'Connor, W T, Ungerstedt, U, French, E D

“…The effects of local perfusion of the ventral tegmental area (VTA) with N-methyl-D-aspartic acid (NMDA) on extracellular dopamine concentrations in the nucleus…”
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NMDA, kainate, and AMPA depolarize nondopamine neurons in the rat ventral tegmentum by Wang, Ting, French, Edward D.

“…The possible existence of N-methyl- d-aspartate (NMDA) and non-NMDA receptors on electrophysiologically identified nondopamine neurones in the ventral…”
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Effects of ethanol on CA1 and CA3 pyramidal cells in the hippocampal slice preparation: an intracellular study by Siggins, G R, Pittman, Q J, French, E D

“…Superfusion of ethanol (10-350 mM) sometimes caused weak hyperpolarization, but more often elicited weak depolarization or biphasic depolarizing,…”
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Opioid Peptides May Excite Hippocampal Pyramidal Neurons by Inhibiting Adjacent Inhibitory Interneurons by Zieglgänsberger, W., French, E. D., Siggins, G. R., Bloom, F. E.

“…The atypical excitation by opiates and opioid peptides of hippocampal pyramidal cells can be antagonized by iontophoresis of naloxone, the γ-aminobutyric acid…”
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Cocaine self-administration and naltrindole, a delta-selective opioid antagonist by Reid, L D, Glick, S D, Menkens, K A, French, E D, Bilsky, E J, Porreca, F

“…Recent reports from several laboratories have suggested a role for delta opioid receptors in expressing some of the biochemical and behavioral effects of…”
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Effects of phencyclidine on ventral tegmental A10 dopamine neurons in the rat by French, E D

“…Extracellular single unit recordings were used to determine the effects of systemically and iontophoretically applied phencyclidine on…”
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Activation of the A10 mesolimbic system by the sigma-receptor agonist (+)SKF 10,047 can be blocked by rimcazole, a novel putative antipsychotic by Ceci, A, Smith, M, French, E D

“…This study evaluated with electrophysiological and behavioral techniques the ability of rimcazole, a novel putative antipsychotic and selective sigma-receptor…”
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Competitive NMDA receptor antagonists attenuate phencyclidine-induced excitations of A10 dopamine neurons by French, E D

“…The binding of phencyclidine (PCP) within the channel gated by the NMDA-receptor complex can be positively or negatively modulated by compounds which…”
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Intrahippocampal kainic acid, seizures and local neuronal degeneration: relationships assessed in unanesthetized rats by French, E D, Aldinio, C, Schwarcz, R

“…Intrahippocampal infusion of nanogram amounts of the neurotoxin kainic acid were used to investigate possible relationships between the convulsive and the…”
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Effects of remoxipride, an atypical antipsychotic, on cocaine self-administration in the rat using fixed- and progressive-ratio schedules of reinforcement by Bourland, James A., French, Edward D.

“…Remoxipride, a selective D2-dopamine receptor antagonist with preferential activity for mesolimbic-mediated behaviors, was assessed for its potential to block…”
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Focal injection of aminooxyacetic acid produces seizures and lesions in rat hippocampus: evidence for mediation by NMDA receptors by McMaster, O G, Du, F, French, E D, Schwarcz, R

“…Aminooxyacetic acid (AOAA), a potent yet nonspecific transaminase inhibitor, is known to cause convulsions when administered at high doses to experimental…”
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Non-competitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons by French, E D, Ceci, A

“…The response of ventral tegmental (VTA) A10 dopamine neurons to a series of compounds covering the spectrum from high-affinity phencyclidine receptor ligands…”
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Effects of acute and chronic administration of phencyclidine on the A10 dopaminergic mesolimbic system: electrophysiological and behavioral correlates by French, E D

“…Electrophysiological and behavioral methods were used to evaluate the effects of chronic exposure to phencyclidine (PCP, 5 mg/kg/day for 30 days) on ventral…”
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