Search Results - "Freitas Pereira de Souza, Gabriela"
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Glutamic acid promotes hair growth in mice
Published in Scientific reports (29-07-2021)“…Glutamic acid is the main excitatory neurotransmitter acting both in the brain and in peripheral tissues. Abnormal distribution of glutamic acid receptors…”
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S-Nitroso-N-Acetylcysteine Ameliorates Ischemia-Reperfusion Injury In The Steatotic Liver
Published in Clinics (São Paulo, Brazil) (2010)“…Steatosis is currently the most common chronic liver disease and it can aggravate ischemia-reperfusion (IR) lesions. We hypothesized that…”
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Assessment of tropane alkaloid levels in Brazilian buckwheat flour products: A novel LC-UHPLC-MS/MS approach using solid-liquid extraction at low temperature
Published in Food chemistry (16-04-2024)“…In recent years, the monitoring of tropane alkaloids, specifically hyoscyamine and scopolamine, in food has become a pressing concern. This is due to…”
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Quantification of florfenicol and its metabolites in fillets of Nile tilapia: Synthesis of metabolites and validation of an on-line solid-phase extraction-ultra high-performance liquid chromatography-tandem mass spectrometry method
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-10-2024)“…•Florfenicol metabolites synthesized with standard lab techniques.•High linearity (>0.99) and ±10 % accuracy confirmed in fish analysis.•Consistent detection…”
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Assessment of ocular surface toxicity after topical instillation of nitric oxide donors
Published in Arquivos brasileiros de oftalmologia (01-01-2013)“…To evaluate the ocular surface toxicity of two nitric oxide donors in ex vivo and in vivo animal models: S-nitrosoglutathione (GSNO) and…”
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Intratablet S-nitrosation: A New Approach for the Oral Administration of S-nitrosothiols as Nitric Oxide Donors
Published in Journal of pharmaceutical sciences (01-01-2016)“…The primary S-nitrosothiol, S-nitroso-N-acetylcysteine (SNAC) is a nitric oxide donor with potential pharmaceutical applications for the oral treatment of…”
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Bactericidal effect of S-nitrosothiols against clinical isolates from keratitis
Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2012)“…The purpose of this study was to evaluate the antimicrobial activity of two nitric oxide donors, ie, S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylcysteine…”
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S-nitrosoglutathione (GSNO) is cytotoxic to intracellular amastigotes and promotes healing of topically treated Leishmania major or Leishmania braziliensis skin lesions
Published in Journal of antimicrobial chemotherapy (01-11-2013)“…This study was designed to verify the cytotoxic activity of S-nitrosoglutathione (GSNO) against intracellular Leishmania amastigotes and to test its efficacy…”
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S‐Nitrosoglutathione Decreases Inflammation and Bone Resorption in Experimental Periodontitis in Rats
Published in Journal of periodontology (1970) (01-04-2012)“…Background: S‐nitrosoglutathione (GSNO) is a nitric oxide donor that may exert antioxidant, anti‐inflammatory, and microbicidal actions and is thus a potential…”
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Leishmanicidal activity of primary S-nitrosothiols against Leishmania major and Leishmania amazonensis: Implications for the treatment of cutaneous leishmaniasis
Published in Nitric oxide (01-11-2006)“…Nitric oxide (NO) is considered a key molecule in the defense against intracellular pathogens, particularly Leishmania. The expression of inducible nitric…”
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A comprehensive LC-UHPLC-MS/MS method for the monitoring of N-nitrosamines in lipophilic drugs: A case study with rifampicin
Published in Journal of pharmaceutical and biomedical analysis (30-11-2023)“…In the last five years, the presence of N-nitrosamines in commonly used medicines has become a significant concern for patients, physicians, and the…”
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S-Nitrosoglutathione incorporated in poly(ethylene glycol) matrix: potential use for topical nitric oxide delivery
Published in Nitric oxide (01-11-2004)“…Incorporation of nitric oxide (NO) donors in non-toxic polymeric matrices can be a useful strategy for allowing topical NO delivery. We have incorporated the…”
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