Search Results - "Freitas, Túlio Resende"

Discovery of Lead 2‑Thiazolylhydrazones with Broad-Spectrum and Potent Antifungal Activity by Oliveira, Nereu Junio Cândido, dos Santos Júnior, Valtair Severino, Pierotte, Isabella Campolina, Leocádio, Victor Augusto Teixeira, Santana, Luiz Felipe de Andrade, Marques, Gabriel Vitor de Lima, Protti, Ícaro Ferrari, Braga, Saulo Fehelberg Pinto, Kohlhoff, Markus, Freitas, Túlio Resende, Sabino, Adriano de Paula, Kronenberger, Thales, Gonçalves, José Eduardo, Johann, Susana, Santos, Daniel A., César, Isabela da Costa, Maltarollo, Vinícius Gonçalves, Oliveira, Renata Barbosa

“…Opportunistic fungal infections represent a global health problem, mainly for immunocompromised individuals. New therapeutical options are needed since several…”
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Isolation and In Vitro Biological Evaluation of Triterpenes from Salacia grandifolia Leaves by Renan Oliveira, Leila, Sá Magalhães Serafim, Mateus, Lanza Dias, Diego, Freitas, Túlio Resende, Abrahao, Jonatas Santos, de Medeiros Antar, Guilherme, Mota, Bruno E. F., Sabino, Adriano de Paula, Pains Duarte, Lucienir, Vidal, Diogo Montes, Faria de Sousa, Grasiely

“…Salacia grandifolia is naturally found in the Atlantic Forest regions of Brazil. Despite the pharmacological potential of plants from the Salacia genus,…”
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New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells by Garcia, Israel José Pereira, de Oliveira, Gisele Capanema, de Moura Valadares, Jéssica Martins, Banfi, Felipe Finger, Andrade, Silmara Nunes, Freitas, Túlio Resende, dos Santos Monção Filho, Evaldo, Lima Santos, Hérica de, Júnior, Gerardo Magela Vieira, Chaves, Mariana Helena, de Jesus Rodrigues, Domingos, Sanchez, Bruno Antonio Marinho, Varotti, Fernando P., Barbosa, Leandro Augusto

“…•A bufadienolide extracted from cane toad (compound 1) inhibits Na,K-ATPase.•Compound 1 decreases Na,K-ATPase expression.•Compound 1 activates caspase 3 and 9…”
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SARS-CoV-2 Omicron BA.1, BA.2, and XAG identification during routine surveillance on a university campus in Belo Horizonte, Brazil, 2022 by Queiroz, Daniel Costa, Carobin, Natália Virtude, de Araújo e Santos, Luiza Campos Guerra, Fonseca, Paula Luize Camargos, Braga-Paz, Isabela Lorraine, Dias, Rillery Calixto, Ferreira, Jorge Gomes Goulart, Freitas, Túlio Resende, Menezes, Diego, Nolasco, Sílvia Cristina Verde Mendes, Ribeiro, Simone Rodrigues, Ribeiro, Thaís Salviana, do Amaral Xavier, Laura, Gomes, Karina Braga, de Paula Sabino, Adriano, de Aguiar, Renato Santana, de Souza, Renan Pedra

“…We report SARS-CoV-2 genomic surveillance results between Belo Horizonte, Brazil’s third and fourth case waves. Samples were obtained through a routine…”
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Computer-aided molecular design, synthesis and evaluation of antifungal activity of heterocyclic compounds by Oliveira, Nereu Junio Cândido, Teixeira, Iasmin Natália Santos, Fernandes, Philipe Oliveira, Veríssimo, Gabriel Corrêa, Valério, Aline Dias, Moreira, Carolina Paula de Souza, Freitas, Túlio Resende, Fonseca, Anna Clara Ventura, Sabino, Adriano de Paula, Johann, Susana, Maltarollo, Vinicius Gonçalves, de Oliveira, Renata Barbosa

“…•Virtual screening techniques were applied for the identification of novel hits.•Heterocyclic compounds were synthesized and tested in vitro as antifungal…”
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Synthesis and Cytotoxic Studies of Pyrrole and Pyrrolidine Derivatives in Human Tumor Cell Lines by Lino, Cleudiomar Inácio, Freitas, Túlio Resende, Villarreal, Jesus Alberto Avendaño, Santos, Eduardo Nicolau, Lula, Ivana, Paula Sabino, Adriano, Maltarollo, Vinícius Gonçalves, Oliveira, Renata Barbosa

“…Heterocyclic compounds such as pyrrole and pyrrolidine derivatives have a broad spectrum of biological activity, being widely used as pharmacophore to design…”
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Clinical Peptidomics in Acute Leukemias: Current Advances and Future Perspectives by Coutinho, Danila Felix, Freitas, Túlio Resende, Silva Batista, Ana Carolina, Quezado de Magalhães, Mariana Torquato, Sabino, Adriano de Paula

“…The study of circulating peptides in the blood offers significant opportunities for diagnosing, stratifying, and managing various diseases. With recent…”
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RAP1-GTPase immunostaining is altered in human precancerous and cancerous cervical lesions by de Vasconcelos, Paula Cristina, Freitas, Tulio Resende, de Araújo Lopes, Lara Verônica, Peixoto, Larissa Rodrigues, Xavier, Marcelo Pascoal, Cançado Figueiredo, Anna Carolina, Dias, Karolina Lopes, de Oliveira, Jaqueline Germano, de Oliveira Salles, Paulo Guilherme, Vago, Annamaria Ravaro, de Paula Sabino, Adriano, de Lima Rocha, Maria Gabrielle

“…This study investigated RAP1 immunostaining variation in different cell types during CC progression. Paraffin-embedded cervical tissues from 101 patients were…”
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Virtual Screening of Adenylate Kinase 3 Inhibitors Employing Pharmacophoric Model, Molecular Docking, and Molecular Dynamics Simulations as Potential Therapeutic Target in Chronic Lymphocytic Leukemia by Barbosa, Bárbara Lima Fonseca, Freitas, Tulio Resende, Almeida, Michell de Oliveira, Araújo, Sérgio Schusterschitz da Silva, Andrade, Ana Clara, Dornelas, Geovana Gomes, Fiorotto, Julyana Gayva, Maltarollo, Vinicius Gonçalves, Sabino, Adriano de Paula

“…Adenylate kinase 3 (AK3) is an enzyme located in the mitochondrial matrix involved in purine homeostasis. This protein has been considered a potential…”
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