Search Results - "Freitas, Julio Cesar de"
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Inhibition of N-linked glycosylation by tunicamycin induces E-cadherin-mediated cell–cell adhesion and inhibits cell proliferation in undifferentiated human colon cancer cells
Published in Cancer chemotherapy and pharmacology (01-07-2011)“…Purpose Aberrant protein glycosylation and disassembly of E-cadherin-mediated cell–cell adhesion are characteristics of epithelial cancer. However, the…”
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2
PI3K/Akt and GSK-3β prevents in a differential fashion the malignant phenotype of colorectal cancer cells
Published in Journal of cancer research and clinical oncology (01-11-2010)“…Purpose During colorectal cancer progression, the loss of differentiation and cell-cell adhesion as well as a higher migratory potential are well-defined…”
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3
Zoonosis in dogs and cats attended by the Birth Control Project: Toxoplasma gondii, Leishmania spp. and Leptospira spp., serodiagnosis and epidemiology
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (01-01-2015)“…Increasing human-animal proximity has also increased risks of zoonotic disease transmission. This study measured the prevalence of anti-Toxoplasma gondii,…”
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4
N-glycan biosynthesis inhibitors induce in vitro anticancer activity in colorectal cancer cells
Published in Journal of cellular biochemistry (01-09-2012)“…During malignant transformation, changes in the expression profile of glycans may be involved in a variety of events, including the loss of cell–cell and…”
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5
The role of N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applications
Published in Oncotarget (12-04-2016)“…Changes in glycosylation, which is one of the most common protein post-translational modifications, are considered to be a hallmark of cancer. N-glycans can…”
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6
Evaluation on the Pathogenesis of Streptococcus agalactiae in Nile Tilapia (Oreochromis niloticus)
Published in Brazilian archives of biology and technology (01-02-2010)“…The pathogenesis of a Streptococcus agalactiae was evaluated in a three-period experiment. Two groups of 40 fishes were intraperitoneally (i.p.) challenged in…”
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7
Serological and molecular findings in diagnosis of leptospirosis serovar hardjo in a dairy bovine herd
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (03-10-2017)“…The cattle are considered hosts of the Hardjo serovar, causing economic damages due to the reproductive failures like abortions and infertility. The serovar…”
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Toxoplasmosis, leptospirosis and brucellosis in stray dogs housed at the shelter in Umuarama municipality, Paraná, Brazil
Published in The journal of venomous animals and toxins including tropical diseases (25-09-2013)“…Leptospirosis, toxoplasmosis and brucellosis are diseases with worldwide distribution. Among stray dogs, these zoonoses are facilitated by direct contact with…”
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9
Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT-Like Phenotype and Activate Wnt/β-Catenin Pathway
Published in Journal of cellular biochemistry (01-12-2014)“…ABSTRACT Radiotherapy remains a major approach to adjuvant therapy for patients with advanced colorectal cancer, however, the fractionation schedules…”
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Serological diagnosis and molecular characterization of Leptospira spp. in the blood and urine of bovine females from refrigerated slaughterhouses
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (01-05-2018)“…Leptospirosis is an important socioeconomic disease in humans, as well as in domestic and wild animals, being caused by Leptospira spp. Bovine animals are…”
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11
Glycans as Regulatory Elements of the Insulin/IGF System: Impact in Cancer Progression
Published in International journal of molecular sciences (07-09-2017)“…The insulin/insulin-like growth factor (IGF) system in mammals comprises a dynamic network of proteins that modulate several biological processes such as…”
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12
Toxoplasmosis, leptospirosis, and brucellosis seroepidemiology in veterinary medical students and their relation with unique health
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (22-07-2017)“…Toxoplasmosis, leptospirosis, and brucellosis are global zoonoses, with humans as accidental participants in their transmission cycles. The can also be…”
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13
Cytotoxicity of citral against melanoma cells: The involvement of oxidative stress generation and cell growth protein reduction
Published in Tumor biology (01-03-2017)“…Citral is a natural compound that has shown cytotoxic and antiproliferative effects on breast and hematopoietic cancer cells; however, there are few studies on…”
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N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells
Published in Oncology reports (01-10-2020)“…Changes in protein levels in different components of the apical junctional complex occur in colorectal cancer (CRC).Claudin-3 is one of the main constituents…”
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A serological survey of agents causing leptospirosis and toxoplasmosis in Rattus rattus in the city of Umuarama, northwest Paraná, Brazil
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (01-01-2017)“…Synanthropic rodents, present in both urban and rural areas, are responsible for the zoonotic transmission of several diseases to humans as well as for…”
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Leptospirosis and brucellosis seroepidemiology in sheep and dogs from non-mechanized rural properties in the northwestern region in the state of Paraná
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (26-10-2016)“…Sheep breeding has been important in agribusiness, transforming the Brazilian productive scenario. However, it is still deficient due to the damages caused by…”
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Dual inhibition of histone deacetylases and phosphoinositide 3‐kinases: effects on Burkitt lymphoma cell growth and migration
Published in Journal of leukocyte biology (01-04-2016)“…The HDACi/PI3Ki combination suppresses BL cell proliferation and migration through alterations in PI3K signaling and HDAC function. Burkitt lymphoma is a…”
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EphA4-mediated signaling regulates the aggressive phenotype of irradiation survivor colorectal cancer cells
Published in Tumor biology (01-09-2016)“…Radiotherapy is widely used for advanced rectal tumors. However, tumor recurrence after this treatment tends to be more aggressive and is associated with a…”
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Epidemiological status of bovine leptospirosis in the State of Paraná, Brazil
Published in Semina. Ciências agrárias : revista cultural e científica da Universidade Estadual de Londrina (01-01-2015)“…The objective of this study was to determine the prevalence of antibodies against Leptospira spp and their geographic distribution and to identify the risk…”
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Insulin/IGF-I signaling pathways enhances tumor cell invasion through bisecting GlcNAc N-glycans modulation. an interplay with E-cadherin
Published in PloS one (25-11-2013)“…Changes in glycosylation are considered a hallmark of cancer, and one of the key targets of glycosylation modifications is E-cadherin. We and others have…”
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