Search Results - "Freije, William A."
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Gene expression profiling of gliomas strongly predicts survival
Published in Cancer research (Chicago, Ill.) (15-09-2004)“…In current clinical practice, histology-based grading of diffuse infiltrative gliomas is the best predictor of patient survival time. Yet histology provides…”
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Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells
Published in Journal of neuroscience research (01-01-2008)“…Emerging evidence suggests that neural stem cells and brain tumors regulate their proliferation via similar pathways. In a previous study, we demonstrated that…”
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3
Distinct transcription profiles of primary and secondary glioblastoma subgroups
Published in Cancer research (Chicago, Ill.) (2006)“…Glioblastomas are invasive and aggressive tumors of the brain, generally considered to arise from glial cells. A subset of these cancers develops from…”
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Maternal Embryonic Leucine Zipper Kinase (MELK) Regulates Multipotent Neural Progenitor Proliferation
Published in The Journal of cell biology (01-08-2005)“…Maternal embryonic leucine zipper kinase (MELK) was previously identified in a screen for genes enriched in neural progenitors. Here, we demonstrate expression…”
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Maternal perinatal calorie restriction temporally regulates the hepatic autophagy and redox status in male rat
Published in Free radical biology & medicine (01-01-2019)“…Intrauterine growth restriction (IUGR) leads to adult obesity, cardiovascular disease, and non-alcoholic fatty liver disease/steatohepatitis. Animal models…”
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Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: immunohistochemical studies
Published in Clinical endocrinology (Oxford) (01-12-2000)“…Adrenarche is considered to occur as a result of intra‐adrenal changes in steroidogenic enzymes involved in C19 steroid production. The present study was…”
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Metabolic Control of G1-S Transition: Cyclin E Degradation by p53-Induced Activation of the Ubiquitin-Proteasome System
Published in The Journal of cell biology (22-02-2010)“…Cell cycle progression is precisely regulated by diverse extrinsic and intrinsic cellular factors. Previous genetic analysis in Drosophila melanogaster has…”
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The Hepatic Transcriptome of Young Suckling and Aging Intrauterine Growth Restricted Male Rats
Published in Journal of cellular biochemistry (01-04-2015)“…ABSTRACT Intrauterine growth restriction leads to the development of adult onset obesity/metabolic syndrome, diabetes mellitus, cardiovascular disease,…”
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Expression profiling of attenuated mitochondrial function identifies retrograde signals in Drosophila
Published in G3 : genes - genomes - genetics (01-08-2012)“…Mitochondria are able to modulate cell state and fate during normal and pathophysiologic conditions through a nuclear-mediated mechanism collectively termed as…”
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MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: Implications in breast cancer
Published in Cancer research (Chicago, Ill.) (15-12-2003)“…Apoptosis is regulated by a series of biochemical events that commits a cell to death. We are interested in understanding and have been investigating the…”
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Genome biology and gynecology: the application of oligonucleotide microarrays to leiomyomata
Published in Fertility and sterility (01-08-2003)Get more information
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Abstract 313: Perinatal Growth Restriction Decreases Hepatic RNA Editing of Apolipoprotein B in Male Rat Offspring
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2015)“…Abstract only Introduction: Individuals born with intrauterine growth restriction develop cardiovascular disease. We employed hepatic microarray-based…”
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Expression of 11 beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) in the human fetal adrenal
Published in Journal of the Society for Gynecologic Investigation (01-11-1997)“…To understand better the steroidogenic capacity of the human fetal adrenal (HFA), we evaluated the expression of 11 beta-hydroxylase (CYP11B1) and aldosterone…”
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