Search Results - "Freier, Kolja"

Clinical outcome and prognostic factors in recurrent oral squamous cell carcinoma after primary surgical treatment: a retrospective study by Zittel, Sven, Moratin, Julius, Horn, Dominik, Metzger, Karl, Ristow, Oliver, Engel, Michael, Mrosek, Jan, Freier, Kolja, Hoffmann, Jürgen, Freudlsperger, Christian

“…Objectives Survival for patients with recurrent oral squamous cell carcinoma is usually poor, and the most effective treatment has not yet been clearly…”
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Early bone resorption after vertical bone augmentation - a comparison of calvarial and iliac grafts by Mertens, Christian, Decker, Christian, Seeberger, Robin, Hoffmann, Jürgen, Sander, Anja, Freier, Kolja

“…Objective and aim Severe cases of bone atrophy in the maxilla or mandible are often reconstructed using bone from extraoral donor sides. Most commonly, grafts…”
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Dynamic Up-Regulation of PD-L1 in the Progression of Oral Squamous Cell Carcinoma by Steen, Sonja, Semmelmayer, Karl, Flechtenmacher, Christa, Hoffmann, Jürgen, Freier, Kolja, Horn, Dominik, Hess, Jochen, Freudlsperger, Christian, Moratin, Julius

“…The introduction of immune checkpoint inhibition for recurrent and metastatic head and neck cancer has brought a new treatment option for patients suffering…”
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HLA-E and Its Soluble Form as Indicators of a Sex-Specific Immune Response in Patients with Oral Squamous Cell Carcinoma by Radermacher, Anne, Fehrenz, Michael, Bellin, Tamara, Claßen, Carolina, Möller, Laura, Struckmeier, Ann-Kristin, Wagner, Mathias, Wartenberg, Philipp, Moratin, Julius, Freudlsperger, Christian, Freier, Kolja, Horn, Dominik

“…The human leukocyte antigene E (HLA-E) is associated with tumorigenesis in various cancers. Immunoncology along with sex-specific aspects in cancer therapy are…”
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Age-dependent hemato- and nephrotoxicity in patients with head and neck cancer receiving chemoradiotherapy with weekly cisplatin by Weykamp, Fabian, Seidensaal, Katharina, Rieken, Stefan, Green, Kim, Mende, Stephan, Zaoui, Karim, Freier, Kolja, Adeberg, Sebastian, Debus, Jürgen, Welte, Stefan Ezechiel

“…Background and purpose In cases of simultaneous chemoradiotherapy (CRT), early recognition of toxic side effects is important, as drug discontinuation may…”
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Early bone resorption of free microvascular reanastomized bone grafts for mandibular reconstruction – A comparison of iliac crest and fibula grafts by Mertens, Christian, Decker, Christian, Engel, Michael, Sander, Anja, Hoffmann, Jürgen, Freier, Kolja

“…Abstract Objectives Patients with continuous bone defects of the mandible after ablative tumor surgery need bony reconstruction for proper function and…”
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Survival of patients with oral cavity cancer in Germany by Listl, Stefan, Jansen, Lina, Stenzinger, Albrecht, Freier, Kolja, Emrich, Katharina, Holleczek, Bernd, Katalinic, Alexander, Gondos, Adam, Brenner, Hermann

“…The purpose of the present study was to describe the survival of patients diagnosed with oral cavity cancer in Germany. The analyses relied on data from eleven…”
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Loss of SOX2 expression induces cell motility via vimentin up-regulation and is an unfavorable risk factor for survival of head and neck squamous cell carcinoma by Bayo, Pilar, Jou, Adriana, Stenzinger, Albrecht, Shao, Chunxuan, Gross, Madeleine, Jensen, Alexandra, Grabe, Niels, Mende, Christel Herold, Rados, Pantelis Varvaki, Debus, Juergen, Weichert, Wilko, Plinkert, Peter K., Lichter, Peter, Freier, Kolja, Hess, Jochen

“…Recurrent gain on chromosome 3q26 encompassing the gene locus for the transcription factor SOX2 is a frequent event in human squamous cell carcinoma, including…”
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The role of human papillomavirus in oral squamous cell carcinoma: myth and reality by Kansy, Katinka, Thiele, Oliver, Freier, Kolja

“…Introduction As the traditional risk factors for oral squamous cell carcinoma, especially tobacco, decline, new potential causative agents become the focus of…”
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Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases by Bergmann, Frank, Aulmann, Sebastian, Sipos, Bence, Kloor, Matthias, von Heydebreck, Anja, Schweipert, Johannes, Harjung, Andreas, Mayer, Philipp, Hartwig, Werner, Moldenhauer, Gerhard, Capper, David, Dyckhoff, Gerhard, Freier, Kolja, Herpel, Esther, Schleider, Anja, Schirmacher, Peter, Mechtersheimer, Gunhild, Klöppel, Günter, Bläker, Hendrik

“…Pancreatic acinar cell carcinomas (PACs) are rare but are distinct aggressive neoplasms that phenotypically differ from pancreatic ductal adenocarcinomas…”
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Digital Pathology Scoring of Immunohistochemical Staining Reliably Identifies Prognostic Markers and Anatomical Associations in a Large Cohort of Oral Cancers by Moratin, Julius, Mock, Andreas, Obradovic, Sonja, Metzger, Karl, Flechtenmacher, Christa, Zaoui, Karim, Fröhling, Stefan, Jäger, Dirk, Krauss, Jürgen, Hoffmann, Jürgen, Freier, Kolja, Horn, Dominik, Hess, Jochen, Freudlsperger, Christian

“…Utilizing digital pathology algorithms for the objective quantification of immunohistochemical staining, this study aimed to identify robust prognostic…”
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Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma by Freier, Kolja, Knoepfle, Karl, Flechtenmacher, Christa, Pungs, Susanne, Devens, Frauke, Toedt, Grischa, Hofele, Christof, Joos, Stefan, Lichter, Peter, Radlwimmer, Bernhard

“…Gene copy number aberrations are involved in oral squamous cell carcinoma (OSCC) development. To delineate candidate genes inside critical chromosomal regions,…”
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Subjective and objective appearance of head and neck cancer patients following microsurgical reconstruction and associated quality of life─A cross-sectional study by Kansy, Katinka, Hoffmann, Jürgen, Alhalabi, Obada, Mistele, Nicole, Freier, Kolja, Mertens, Christian, Freudlsperger, Christian, Engel, Michael

“…Depending on the site and size of head and neck cancer, the disease affects patients' appearance and subsequently their quality of life. The aim of this study…”
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The role of elective supraomohyoidal neck dissection in the treatment of early, node-negative oral squamous cell carcinoma (OSCC): A retrospective analysis of 122 cases by Thiele, Oliver C, Seeberger, Robin, Flechtenmacher, Christa, Hofele, Christof, Freier, Kolja

“…Abstract The adequate treatment of the neck in early, clinically node-negative oral squamous cell carcinoma (OSCC) remains controversial. To assess whether…”
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Activation of MAP Kinase Signaling Through ERK5 But Not ERK1 Expression Is Associated with Lymph Node Metastases in Oral Squamous Cell Carcinoma (OSCC) by Sticht, Carsten, Freier, Kolja, Knöpfle, Karl, Flechtenmacher, Christa, Pungs, Susanne, Hofele, Christof, Hahn, Meinhard, Joos, Stefan, Lichter, Peter

“…In an attempt to further elucidate the pathomechanisms in oral squamous cell carcinoma (OSCC), gene expression profiling was performed using a…”
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Neoadjuvant concurrent radiochemotherapy followed by surgery in advanced oral squamous cell carcinoma (OSCC): A retrospective analysis of 207 patients by Freier, Kolja, Engel, Michael, Lindel, Katja, Flechtenmacher, Christa, Mühling, Joachim, Hassfeld, Stefan, Hofele, Christof

“…Summary Locally advanced operable oral squamous cell carcinoma (OSCC) continues to be a major therapeutic challenge despite the implementation of novel…”
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Oral health-related quality of life and depression/anxiety in long-term recurrence-free patients after treatment for advanced oral squamous cell cancer by Hassel, Alexander J, Danner, Daniel, Freier, Kolja, Hofele, Christof, Becker-Bikowski, Kirsten, Engel, Michael

“…Abstract This report focuses on the association between oral health-related quality of life (OHRQoL) and depression/anxiety of a homogeneous group of cancer…”
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Disease control and functional outcome in three modern combined organ preserving regimens for locally advanced squamous cell carcinoma of the head and neck (SCCHN) by Jensen, Alexandra D, Krauss, Jürgen, Weichert, Wilko, Bergmann, Zazie P, Freier, Kolja, Debus, Jürgen, Münter, Marc W

“…To report our experience on disease control and functional outcome using three modern combined-modality approaches for definitive radiochemotherapy of locally…”
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Frequent high telomerase reverse transcriptase expression in primary oral squamous cell carcinoma by Freier, Kolja, Pungs, Susanne, Flechtenmacher, Christa, Bosch, Franz X., Lichter, Peter, Joos, Stefan, Hofele, Christof

“…Background:  Gene copy number gain of chromosomal arm 5p is frequently found in oral squamous cell carcinoma (OSCC) suggesting the activation of…”
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Haemangiopericytoma of the mandible by Thiele, Oliver C., MD, DDS, Freier, Kolja, MD, DDS, Flechtenmacher, Christa, MD, Rohde, Stefan, MD, Hofele, Christof, MD, DDS, Mühling, Joachim, MD, DDS, Seeberger, Robin, MD, DDS

“…Summary Haemangiopericytomas (HPCs) found in bony structures are rare sarcomas of vascular origin. Here, we report the case of a 41-year-old female with a HPC…”
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