Search Results - "Frei, Balz"

Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans? by Frei, Balz, Birlouez-Aragon, Ines, Lykkesfeldt, Jens

“…The recommended dietary allowance (RDA) of vitamin C has traditionally been based on the prevention of the vitamin C deficiency disease, scurvy. While higher…”
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Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults by Blumberg, Jeffrey B, Frei, Balz B, Fulgoni, Victor L, Weaver, Connie M, Zeisel, Steven H

“…Although >50% of U.S. adults use dietary supplements, little information is available on the impact of supplement use frequency on nutrient intakes and…”
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Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction by Li, Chuan, Zhang, Wei-Jian, Frei, Balz

“…Atherosclerosis, the underlying cause of ischemic heart disease and stroke, is an inflammatory disease of arteries in a hyperlipidemic milieu. Endothelial…”
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Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice by Zhang, Wei-Jian, Frei, Balz

“…In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese medicinal herb Astragalus…”
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Coffee and Health: A Review of Recent Human Research by Higdon, Jane V., Frei, Balz

“…Coffee is a complex mixture of chemicals that provides significant amounts of chlorogenic acid and caffeine. Unfiltered coffee is a significant source of…”
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Vitamin C and cancer revisited by Frei, Balz, Lawson, Stephen

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Antioxidant activity of tea polyphenols in vivo: evidence from animal studies by Frei, Balz, Higdon, Jane V

“…Tea is particularly rich in polyphenols, including catechins, theaflavins and thearubigins, which are thought to contribute to the health benefits of tea. Tea…”
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Tea Catechins and Polyphenols: Health Effects, Metabolism, and Antioxidant Functions by Higdon, Jane V., Frei, Balz

“…Increasing interest in the health benefits of tea has led to the inclusion of tea extracts in dietary supplements and functional foods. However, epidemiologic…”
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Efficacy of dietary antioxidants to prevent oxidative damage and inhibit chronic disease by Frei, Balz

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The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis by Díaz-Valdivia, Natalia I., Díaz, Jorge, Contreras, Pamela, Campos, América, Rojas-Celis, Victoria, Burgos-Ravanal, Renato A., Lobos-González, Lorena, Torres, Vicente A., Perez, Viviana I., Frei, Balz, Leyton, Lisette, Quest, Andrew F. G.

“…Caveolin-1 (CAV1) enhanced migration, invasion, and metastasis of cancer cells is inhibited by co-expression of the glycoprotein E-cadherin. Although the two…”
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Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research by Michels, Alexander J, Frei, Balz

“…Research progress to understand the role of vitamin C (ascorbic acid) in human health has been slow in coming. This is predominantly the result of several…”
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Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function by Michels, Alexander J, Hagen, Tory M, Frei, Balz

“…New evidence for the regulation of vitamin C homeostasis has emerged from several studies of human genetic variation. Polymorphisms in the genes encoding…”
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α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway by Zhang, Wei-Jian, Wei, Hao, Hagen, Tory, Frei, Balz

“…The phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway was recently shown to negatively regulate LPS-induced acute inflammatory…”
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Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study by Michels, Alexander J, Butler, Judy A, Uesugi, Sandra L, Lee, Ken, Frei, Balz B, Bobe, Gerd, Magnusson, Kathy R, Hagen, Tory M

“…Despite the reported prevalence of micronutrient deficiencies in older adults, it is not yet established whether multivitamin/multimineral (MV/MM) supplements…”
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The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice by Zhang, Wei-Jian, Wei, Hao, Frei, Balz

“…Vascular inflammation and monocyte recruitment are initiating events in atherosclerosis that have been suggested to be caused, in part, by iron-mediated…”
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Does vitamin C act as a pro-oxidant under physiological conditions? by Carr, A, Frei, B

“…ABSTRACT Vitamin C readily scavenges reactive oxygen and nitrogen species and may thereby prevent oxidative damage to important biological macromolecules such…”
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Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups by Blumberg, Jeffrey B, Frei, Balz, Fulgoni, Victor L, Weaver, Connie M, Zeisel, Steven H

“…Many Americans have inadequate intakes of several nutrients. The Dietary Guidelines for Americans 2015-2020 specifically identified vitamins A, C, D and E,…”
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Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase by Li, Chuan, Zhang, Wei-Jian, Choi, Jaewoo, Frei, Balz

“…Endothelial dysfunction due to vascular inflammation and oxidative stress critically contributes to the etiology of atherosclerosis. The intracellular redox…”
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Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo by Wei, Hao, Frei, Balz, Beckman, Joseph S, Zhang, Wei-Jian

“…Redox-active transition metal ions, such as iron and copper, may play an important role in vascular inflammation, which is an etiologic factor in…”
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Positive correlation between circulating cathelicidin antimicrobial peptide (hCAP18/LL-37) and 25-hydroxyvitamin D levels in healthy adults by Dixon, Brian M, Barker, Tyler, McKinnon, Toni, Cuomo, John, Frei, Balz, Borregaard, Niels, Gombart, Adrian F

“…Transcription of the cathelicidin antimicrobial peptide (CAMP) gene is induced by binding of the bioactive form of vitamin D, 1,25-dihydroxyvitamin D, to the…”
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