Search Results - "Frei, Anthony W."

Immunosuppressive PLGA TGF-β1 Microparticles Induce Polyclonal and Antigen-Specific Regulatory T Cells for Local Immunomodulation of Allogeneic Islet Transplants by Li, Ying, Frei, Anthony W., Labrada, Irayme M., Rong, Yanan, Liang, Jia-Pu, Samojlik, Magdalena M., Sun, Chuqiao, Barash, Steven, Keselowsky, Benjamin G., Bayer, Allison L., Stabler, Cherie L.

“…Allogeneic islet transplantation is a promising cell-based therapy for Type 1 Diabetes (T1D). The long-term efficacy of this approach, however, is impaired by…”
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In vitro platform establishes antigen-specific CD8+ T cell cytotoxicity to encapsulated cells via indirect antigen recognition by Li, Ying, Frei, Anthony W., Yang, Ethan Y., Labrada-Miravet, Irayme, Sun, Chuqiao, Rong, Yanan, Samojlik, Magdalena M., Bayer, Allison L., Stabler, Cherie L.

“…The curative potential of non-autologous cellular therapy is hindered by the requirement of anti-rejection therapy. Cellular encapsulation within nondegradable…”
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Local delivery of fingolimod from three‐dimensional scaffolds impacts islet graft efficacy and microenvironment in a murine diabetic model by Frei, Anthony W., Li, Ying, Jiang, Kaiyuan, Buchwald, Peter, Stabler, Cherie L.

“…The local delivery of immunosuppressive agents could significantly promote the success of islet transplantation for the treatment of Type 1 diabetes…”
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Incorporation of aggrecan in interpenetrating network hydrogels to improve cellular performance for cartilage tissue engineering by Ingavle, Ganesh C, Frei, Anthony W, Gehrke, Stevin H, Detamore, Michael S

“…Interpenetrating network (IPN) hydrogels were recently introduced to the cartilage tissue engineering literature, with the approach of encapsulating cells in…”
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