Search Results - "Fregien, Nevis L"
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Gefitinib, an EGFR Tyrosine Kinase inhibitor, Prevents Smoke-Mediated Ciliated Airway Epithelial Cell Loss and Promotes Their Recovery
Published in PloS one (17-08-2016)“…Cigarette smoke exposure is a major health hazard. Ciliated cells in the epithelium of the airway play a critical role in protection against the noxious…”
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Submersion and hypoxia inhibit ciliated cell differentiation in a notch-dependent manner
Published in American journal of respiratory cell and molecular biology (01-10-2014)“…The epithelium that lines the conducting airways is composed of several distinct cell types that differentiate from common progenitor cells. The signals that…”
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Mycobacterium abscessus -Bronchial Epithelial Cells Cross-Talk Through Type I Interferon Signaling
Published in Frontiers in immunology (09-12-2019)“…are aerobic non-motile organisms with lipid rich, hydrophobic cell walls that render them resistant to antibiotics. While there are over 150 different species…”
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Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells
Published in Journal of cell science (01-03-2008)“…Atypical protein kinase iota (PKCiota) is a key organizer of the apical domain in epithelial cells. Ezrin is a cytosolic protein that, upon activation by…”
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IL-13 Inhibits Multicilin Expression and Ciliogenesis via Janus Kinase/Signal Transducer and Activator of Transcription Independently of Notch Cleavage
Published in American journal of respiratory cell and molecular biology (01-04-2016)“…Loss of ciliated cells and increases in goblet cells are seen in respiratory diseases such as asthma. These changes result in part from reduced differentiation…”
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Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation
Published in Lung (01-08-2022)“…Purpose Alpha-melanocyte stimulating hormone (α-MSH) is known to have anti-inflammatory effects. However, the anti-inflammatory properties of α-MSH on normal…”
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Electronic Cigarettes Enhance Replication of Mycobacterium abscessus in Airway Epithelial Cells
Published in American journal of respiratory cell and molecular biology (01-06-2019)“…[...]of this perception, ECs have become popular among children in middle school and high school (3). Mycobacterium abscessus (MAB) has been found to be the…”
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Rapid nongenomic actions of inhaled corticosteroids on long-acting β2 -agonist transport in the airway
Published in Pulmonary pharmacology & therapeutics (01-12-2011)“…Abstract Corticosteroids inhibit organic cation transporters (OCTs) that play an important role in drug absorption, tissue distribution and elimination…”
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Optimal Lentivirus Production and Cell Culture Conditions Necessary to Successfully Transduce Primary Human Bronchial Epithelial Cells
Published in Journal of visualized experiments (22-07-2016)“…In vitro culture of primary human bronchial epithelial (HBE) cells using air-liquid interface conditions provides a useful model to study the processes of…”
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Rapid nongenomic actions of inhaled corticosteroids on long-acting β(2)-agonist transport in the airway
Published in Pulmonary pharmacology & therapeutics (01-12-2011)“…Corticosteroids inhibit organic cation transporters (OCTs) that play an important role in drug absorption, tissue distribution and elimination. Corticosteroid…”
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Forskolin increases neuregulin receptors in human Schwann cells without increasing receptor mRNA
Published in Glia (01-01-2005)“…Forskolin and heregulin synergistically drive human Schwann cell (HSC) proliferation in vitro, but the role of forskolin is not completely understood. To learn…”
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Reversible Disruption of Cell-Matrix and Cell-Cell Interactions by Overexpression of Sialomucin Complex
Published in The Journal of biological chemistry (26-12-1997)“…Sialomucin complex (SMC) is a large, heterodimeric glycoprotein complex composed of mucin (ASGP-1) and transmembrane (ASGP-2) subunits and expressed abundantly…”
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Sialomucin complex in the rat respiratory tract: a model for its role in epithelial protection
Published in Biochemical journal (01-03-1998)“…The pulmonary epithelium has a multitude of specialized functions, which depend on regulated growth and differentiation of several cell types. One such…”
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Characterization of the expression and steroid hormone control of sialomucin complex in the rat uterus: Implications for uterine receptivity
Published in Journal of cellular physiology (01-07-1998)“…The sialomucin complex (SMC), originally isolated as a heterodimeric glycoprotein complex from membranes of ascites sublines of a highly metastatic mammary…”
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Rapid nongenomic actions of inhaled corticosteroids on long-acting β 2-agonist transport in the airway
Published in Pulmonary pharmacology & therapeutics (01-12-2011)“…Corticosteroids inhibit organic cation transporters (OCTs) that play an important role in drug absorption, tissue distribution and elimination. Corticosteroid…”
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Journal Article -
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Sialomucin Complex, a Heterodimeric Glycoprotein Complex
Published in The Journal of biological chemistry (27-12-1996)“…Ascites 13762 rat mammary adenocarcinoma cells express abundantly on their cell surfaces a heterodimeric glycoprotein complex composed of a sialomucin ascites…”
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Atypical Protein Kinase C (iota) mediates local ezrin activation in the apical domain of intestinal epithelial cells
Published in Journal of cell science (01-01-2008)“…Atypical Protein Kinase iota (PKCι) is a key organizer of the apical domain in epithelial cells. Ezrin is a cytosolic protein that, upon activation by…”
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Journal Article -
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Sialomucin complex, a heterodimeric glycoprotein complex. Expression as a soluble, secretable form in lactating mammary gland and colon
Published in The Journal of biological chemistry (27-12-1996)“…Ascites 13762 rat mammary adenocarcinoma cells express abundantly on their cell surfaces a heterodimeric glycoprotein complex composed of a sialomucin ascites…”
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