Search Results - "Freemark, M"

Regulation of maternal metabolism by pituitary and placental hormones: roles in fetal development and metabolic programming by Freemark, M

“…This review outlines the regulation of maternal metabolism by hormones, cytokines and growth factors, highlighting recent studies that implicate disordered…”
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Hormone signaling and fatty liver in females: analysis of estrogen receptor α mutant mice by Hart-Unger, S, Arao, Y, Hamilton, K J, Lierz, S L, Malarkey, D E, Hewitt, S C, Freemark, M, Korach, K S

“…Background: Treatment with estrogen in early menopausal women protects against development of hepatic steatosis and nonalcoholic fatty liver disease but…”
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The Effects of Metformin on Body Mass Index and Glucose Tolerance in Obese Adolescents With Fasting Hyperinsulinemia and a Family History of Type 2 Diabetes by Freemark, Michael, Bursey, Deborah

“…The prevalence of type 2 diabetes in American adolescents has increased markedly during the past generation. Although the factors that contribute to the…”
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Advances in science and applications of air pollution monitoring: A case study on oil sands monitoring targeting ecosystem protection by Brook, J.R., Cober, S.G., Freemark, M., Harner, T., Li, S.M., Liggio, J., Makar, P., Pauli, B.

“…The potential environmental impact of air pollutants emitted from the oil sands industry in Alberta, Canada, has received considerable attention. The mining…”
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The roles of placental growth hormone and placental lactogen in the regulation of human fetal growth and development by Handwerger, S, Freemark, M

“…The human growth hormone (hGH)/human placental lactogen (hPL) gene family, which consists of two GH and three PL genes, is important in the regulation of…”
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Obestatin and adropin in Prader‐Willi syndrome and nonsyndromic obesity: Associations with weight, BMI‐z, and HOMA‐IR by Orsso, C. E., Butler, A. A., Muehlbauer, M. J., Cui, H. N., Rubin, D. A., Pakseresht, M., Butler, M. G., Prado, C. M., Freemark, M., Haqq, A. M.

“…Summary The roles of obestatin and adropin in paediatric obesity are poorly understood. We compared obestatin and adropin concentrations in younger (n = 21)…”
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Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance by Freemark, Michael, Avril, Isabelle, Fleenor, Don, Driscoll, Phyllis, Petro, Ann, Opara, Emmanuel, Kendall, Will, Oden, Jon, Bridges, Spencer, Binart, Nadine, Breant, Bernadette, Kelly, Paul A

“…PRL and placental lactogen (PL) stimulate beta-cell proliferation and insulin gene transcription in isolated islets and rat insulinoma cells, but the roles of…”
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Prolactin induction of insulin gene expression: the roles of glucose and glucose transporter-2 by Petryk, A, Fleenor, D, Driscoll, P, Freemark, M

“…Previous studies have shown that lactogenic hormones stimulate beta-cell proliferation and insulin production in pancreatic islets. However, all such studies…”
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Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts by Fowlkes, J, Freemark, M

“…The mechanisms by which insulin-like growth factors (IGFs) reduce IGF-binding protein-4 (IGFBP-4) levels in cellular conditioned media are poorly understood…”
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Autonomic nervous system dysfunction in obesity and Prader-Willi syndrome: current evidence and implications for future obesity therapies by Haqq, A. M., DeLorey, D. S., Sharma, A. M., Freemark, M., Kreier, F., Mackenzie, M. L., Richer, L. P.

“…Summary The autonomic nervous system (ANS) controls essential functions like breathing, heart rate, digestion, body temperature and hormone levels. Evidence…”
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Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development by Freemark, M, Driscoll, P, Maaskant, R, Petryk, A, Kelly, P A

“…To explore potential roles for lactogenic hormones in human fetal development, we examined the distribution and ontogenesis of expression of prolactin…”
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Prolactin receptor signal transduction pathways and actions determined in prolactin receptor knockout mice by Kelly, P A, Binart, N, Freemark, M, Lucas, B, Goffin, V, Bouchard, B

“…Prolactin-receptor-deficient mice are a good model in which to study the various actions of prolactin. Female homozygous knockout mice are completely infertile…”
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Unique metabolic profile in children with Prader-Willi Syndrome: Heightened insulin sensitivity relative to body mass index by Haqq, A.M, Muehlbauer, M.J, Newgard, C.B, Svetkey, L.P, Sharma, A.M, Richer, L.P, Mackenzie, M.L, Mager, D, Grambow, S.C, Freemark, M

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Ontogenesis of prolactin receptor gene expression in the rat olfactory system: potential roles for lactogenic hormones in olfactory development by Freemark, M, Driscoll, P, Andrews, J, Kelly, P A, Royster, M

“…The PRL receptor (PRLR) is expressed at very low levels in the olfactory bulb of the adult rat but is detected in abundance in the olfactory epithelium and…”
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Prolactin receptor gene expression in the fetal rat by Freemark, M, Nagano, M, Edery, M, Kelly, P A

“…The expression of mRNA encoding the long and short forms of the prolactin receptor (PRLR) in the fetal rat was examined using the method of reverse…”
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Human Placental Lactogen Infusions into the Medial Preoptic Area Stimulate Maternal Behavior in Steroid-Primed, Nulliparous Female Rats by Bridges, Robert S., Freemark, Michael S.

“…The effects of central administration of human placental lactogen (hPL) on the onset of maternal behavior were measured in steroid-primed, adult…”
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Ontogenesis of prolactin receptor gene expression in the rat olfactory system: potential roles for lactogenic hormones in olfactory development by Freemark, M, Driscoll, P, Andrews, J, Kelly, P A, Royster, M

“…The PRL receptor (PRLR) is expressed at very low levels in the olfactory bulb of the adult rat but is detected in abundance in the olfactory epithelium and…”
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Ontogenesis of prolactin receptors in the human fetus: roles in fetal development by Freemark, M

“…The lactogenic hormones prolactin (PRL) and placental lactogen circulate in human fetal plasma during mid and late gestation. To explore potential roles for…”
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7718 Dysregulated BCAA catabolism and insulin secretory response in the early stages of insulin resistance in mature adolescents by Basin, A, Wang, Q, Hong, H, Ilkayeva, O, Muehlbauer, M, Hsia, D, D’Alessio, D A, Newgard, C B, Freemark, M, Gumus Balikcioglu, P

“…Abstract Disclosure: A. Basin: None. Q. Wang: None. H. Hong: None. O. Ilkayeva: None. M. Muehlbauer: None. D. Hsia: None. D.A. D'Alessio: None. C.B. Newgard:…”
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Pregnancy lactogens in the rat conceptus and fetus: circulating levels, distribution of binding, and expression of receptor messenger ribonucleic acid by Freemark, M, Kirk, K, Pihoker, C, Robertson, M C, Shiu, R P, Driscoll, P

“…To clarify the roles of the rat placental lactogens in embryogenesis and fetal development, we measured the concentrations of rat placental lactogen-II…”
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