Search Results - "Freeman, TaRynn N Carder"
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Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands
Published in Bioorganic & medicinal chemistry (01-07-2014)“…Several metal complexes of macrocyclic polyamines were synthesized and shown to have potent antimalarial activity when compared with their metal-free ligands…”
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Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads
Published in Polyhedron (01-05-2019)“…Several bis-aryl-monocyclic polyamines and their metal complexes were shown to be potent in vitro inhibitors of Leishmania donovani. The synthesis of the two…”
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Discovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes
Published in Antimicrobial agents and chemotherapy (01-09-2016)“…Praziquantel (PZQ) is the only drug available for the treatment of schistosomiasis, and since its large-scale use might be associated with the onset of…”
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CXCR4 chemokine receptor antagonists: nickel(II) complexes of configurationally restricted macrocycles
Published in Dalton transactions : an international journal of inorganic chemistry (01-01-2012)“…Tetraazamacrocyclic complexes of transition metals provide useful units for incorporating multiple coordination interactions into a single protein binding…”
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