Search Results - "Freeman, Ronald"

Leptin: Linking obesity, the metabolic syndrome, and cardiovascular disease by Patel, Sanjeev B., Reams, Garry P., Spear, Robert M., Freeman, Ronald H., Villarreal, Daniel

“…The incidence and prevalence of obesity and the metabolic syndrome have risen markedly in the past decade, representing a serious cardiovascular health hazard…”
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Obesity Hypertension: Pathophysiological Role of Leptin in Neuroendocrine Dysregulation by Go, Orson, MD, Liu, Kan, PhD, MD, Villarreal, Daniel, MD, Spear, Robert, MS, Freeman, Ronald H., PhD, Reams, Garry P., MD, Weber, Karl T., MD

“…Abstract Leptin is a 16-kDa peptide hormone that is primarily synthesized and secreted by adipose tissue. One of the major actions of this hormone is the…”
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Obesity hypertension: the emerging role of leptin in renal and cardiovascular dyshomeostasis by Kshatriya, Shilpa, Reams, Garry P, Spear, Robert M, Freeman, Ronald H, Dietz, John R, Villarreal, Daniel

“…PURPOSE OF REVIEWAdipose tissue is now considered to be an active physiologic system operating in concert with multiple other organs. Leptin is a peptide…”
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Obesity Hypertension: The Regulatory Role of Leptin by Villarreal, Daniel, Reams, Garry P., Freeman, Ronald H., Spear, Robert M., Szombathy, Tamas, Salah, Ali, Kshatriya, Shilpa, Liu, Kan

“…Leptin is a 16-kDa-peptide hormone that is primarily synthesized and secreted by adipose tissue. One of the major actions of this hormone is the control of…”
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Obesity-hypertension: emerging concepts in pathophysiology and treatment by Mathew, Boban, Patel, Sanjeev B, Reams, Garry P, Freeman, Ronald H, Spear, Robert M, Villarreal, Daniel

“…The incidence and prevalence of obesity has risen markedly in the last decade, and this epidemic represents a serious health hazard with significant morbidity…”
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Renal effects of leptin in normotensive, hypertensive, and obese rats by Villarreal, D, Reams, G, Freeman, R.H, Taraben, A

“…The hemodynamic, hormonal, and renal excretory effects of intravenous bolus administration of synthetic murine leptin were examined in groups of anesthetized…”
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Effects of chronic nitric oxide inhibition on the renal excretory response to leptin by Villarreal, D, Reams, G, Samar, H, Spear, R, Freeman, R.H

“…Objective: Previous investigations have demonstrated that leptin promotes natriuresis with a renal tubular effect. However, the mechanisms involved in this…”
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Guanylin peptides: renal actions mediated by cyclic GMP by Forte, L R, London, R M, Freeman, R H, Krause, W J

“…The guanylin family of cGMP-regulating peptides has three subclasses of peptides containing either three intramolecular disulfides found in bacterial…”
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Effects of renal denervation on the sodium excretory actions of leptin in hypertensive rats by Villarreal, Daniel, Reams, Garry, Freeman, Ronald H.

“…Effects of renal denervation on the sodium excretory actions of leptin in hypertensive rats. Previous studies from this laboratory have reported a marked…”
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Mechanisms of guanylin action via cyclic GMP in the kidney by Forte, L R, London, R M, Krause, W J, Freeman, R H

“…Guanylin, uroguanylin, and lymphoguanylin are small peptides that activate cell-surface guanylate cyclase receptors and influence cellular function via…”
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Role of leptin in the regulation of body fluid volume and pressures by Guha, Prabal K, Villarreal, Daniel, Reams, Garry P, Freeman, Ronald H

“…Leptin is a circulating polypeptide hormone produced by an adipocyte-specific gene. It regulates energy balance by binding to receptors in the hypothalamus,…”
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Lymphoguanylin: Cloning and Characterization of a Unique Member of the Guanylin Peptide Family by Forte, Leonard R, Eber, Sammy L, Fan, Xiaohui, London, Roslyn M, Wang, Yuan, Rowland, Linda M, Chin, David T, Freeman, Ronald H, Krause, William J

“…Guanylin and uroguanylin are small peptides containing two disulfide bonds that activate membrane guanylate cyclase-receptors in the intestine, kidney and…”
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Signaling Pathways for Guanylin and Uroguanylin in the Digestive, Renal, Central Nervous, Reproductive, and Lymphoid Systems by Fan, Xiaohui, Wang, Yuan, London, Roslyn M, Eber, Sammy L, Krause, William J, Freeman, Ronald H, Forte, Leonard R

“…Guanylin and uroguanylin are peptides that stimulate membrane guanylate cyclases (GC) and regulate intestinal and renal function via cGMP. Complementary DNAs…”
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Sustained hypertension in the rat induced by chronic blockade of nitric oxide production by Johnson, R A, Freeman, R H

“…It is well established that acute systemic blockage of L-arginine conversion to nitric oxide by NW-nitro-L-arginine methyl ester (L-NAME) and other substituted…”
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Pressure Natriuresis in Rats During Blockade of the L-Arginine/Nitric Oxide Pathway by Johnson, Robert A, Freeman, Ronald H

“…The natriuretic response was studied in anesthetized rats during the intravenous infusion of L-arginine analogues to inhibit the production of…”
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Natriuretic peptides and salt sensitivity: endocrine cardiorenal integration in heart failure by Villarreal, Daniel, Freeman, Ronald H, Reams, Garry P

“…Mammalian hearts contain a family of peptides with potent natriuretic, diuretic, and vasorelaxant actions. In addition to atrial natruretic peptide (ANP) and…”
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Structure and activity of uroguanylin and guanylin from the intestine and urine of rats by Fan, X, Hamra, F K, London, R M, Eber, S L, Krause, W J, Freeman, R H, Smith, C E, Currie, M G, Forte, L R

“…Uroguanylin and guanylin are related peptides that activate common guanylate cyclase signaling molecules in the intestine and kidney. Uroguanylin was isolated…”
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Pressure-Dependent Renin Release During Chronic Blockade of Nitric Oxide Synthase by Knoblich, Penny R, Freeman, Ronald H, Villarreal, Daniel

“…We evaluated pressure-dependent stimulation of renin release in rats with sustained hypertension induced by chronic blockade of nitric oxide synthase with N…”
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John Wesley Meets Malcolm Knowles: Was The Class Meeting Andragogical? by Budd, Clair Allen, Freeman, Ronald W.

“…With increased interest in small groups as a device for facilitating spiritual growth and maturity, several recent studies have reconsidered the remarkable…”
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INTEGRATION OF NEUROSCIENCE AND ENDOCRINOLOGY IN HYBRID PBL CURRICULUM by Cunningham, J. Thomas, Freeman, Ronald H, Hosokawa, Michael C

“…Departments of Physiology and Family and Community Medicine, Dalton Cardiovascular Research Center, School of Medicine, University of Missouri-Columbia,…”
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