Search Results - "Freeman, Michael B"

Contemporary outcomes of vertebral artery injury by Alterman, Daniel M., MD, Heidel, Richard E., PhD, Daley, Brian J., MD, Grandas, Oscar H., MD, Stevens, Scott L., MD, Goldman, Mitchell H., MD, Freeman, Michael B., MD

“…Objective Vertebral artery injury (VAI) associated with cervical trauma is being increasingly recognized with more aggressive screening. Disparate results from…”
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Testosterone replacement attenuates intimal hyperplasia development in an androgen deficient model of vascular injury by Freeman, Brian M., MD, Univers, Junior, MD, Fisher, Richard K., MS, Kirkpatrick, Stacy S, Klein, Frederick A., MD, Freeman, Michael B., MD, Mountain, Deidra J.H., PhD, Grandas, Oscar H., MD

“…Abstract Background Androgen deficiency (AD) is associated with increased risk of vascular disease. Dysfunctional remodeling of the vessel wall and atypical…”
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Liposomal Nanocarriers Designed for Sub-Endothelial Matrix Targeting under Vascular Flow Conditions by Grimsley, Lauren B., West, Phillip C., McAdams, Callie D., Bush, Charles A., Kirkpatrick, Stacy S., Arnold, Joshua D., Buckley, Michael R., Dieter, Raymond A., Freeman, Michael B., McNally, Michael M., Stevens, Scott L., Grandas, Oscar H., Mountain, Deidra J. H.

“…Vascular interventions result in the disruption of the tunica intima and the exposure of sub-endothelial matrix proteins. Nanoparticles designed to bind to…”
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Regulation of vascular smooth muscle cell expression and function of matrix metalloproteinases is mediated by estrogen and progesterone exposure by Grandas, Oscar H., MD, Mountain, Deidra H., PhD, Kirkpatrick, Stacy S, Cassada, David C., MD, Stevens, Scott L., MD, Freeman, Michael B., MD, Goldman, Mitchell H., MD

“…Objective Postmenopausal women receiving hormone replacement therapy (HRT) have been reported to have more adverse outcomes after vascular reconstructions,…”
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Iliac artery stenting versus surgical reconstruction for TASC (transatlantic inter-society consensus) type B and type C iliac lesions by Timaran, Carlos H, Prault, Trent L, Stevens, Scott L, Freeman, Michael B, Goldman, Mitchell H

“…The TransAtlantic Inter-Society Consensus (TASC) document did not define the best treatment for moderately severe iliac artery lesions, ie, TASC type B and…”
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Can Screening Items Identify Surgery Patients at Risk of Limited Health Literacy? by Wallace, Lorraine S., Ph.D, Cassada, David C., M.D, Rogers, Edwin S., Ph.D, Freeman, Michael B., M.D, Grandas, Oscar H., M.D, Stevens, Scott L., M.D, Goldman, Mitchell H., M.D

“…Background Health literacy skills (HLS) have been shown to have a major impact on patient outcomes. To identify patients with limited or marginal HLS, the…”
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Advances in the Formulation and Assembly of Non-Cationic Lipid Nanoparticles for the Medical Application of Gene Therapeutics by Fisher, 3rd, Richard K, West, Phillip C, Mattern-Schain, Samuel I, Best, Michael D, Kirkpatrick, Stacy S, Dieter, 3rd, Raymond A, Arnold, Joshua D, Buckley, Michael R, McNally, Michael M, Freeman, Michael B, Grandas, Oscar H, Mountain, Deidra J H

“…Lipid nanoparticles have become increasingly popular delivery platforms in the field of gene therapy, but bench-to-bedside success has been limited. Many…”
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Comparative analysis of polymers for short interfering RNA delivery in vascular smooth muscle cells by Bools, Lindsay M., MD, Fisher, Richard K., MS, Grandas, Oscar H., MD, Kirkpatrick, Stacy S., BS, Arnold, Joshua D., MD, Goldman, Mitchell H., MD, Freeman, Michael B., MD, Mountain, Deidra J.H., PhD

“…Abstract The use of short interfering RNA (siRNA) to degrade messenger RNA in the cell cytoplasm and transiently attenuate intracellular proteins shows promise…”
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Role of MT1-MMP in Estrogen-Mediated Cellular Processes of Intimal Hyperplasia by Mountain, Deidra J.H., Ph.D, Kirkpatrick, Stacy S., B.S, Freeman, Michael B., M.D, Stevens, Scott L., M.D, Goldman, Mitchell H., M.D, Grandas, Oscar H., M.D

“…Background Hormone replacement therapy increases intimal hyperplasia (IH) following vascular intervention. Matrix metalloproteinases (MMPs) play a role in IH…”
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Androgens regulate MMPs and the cellular processes of intimal hyperplasia by Mountain, Deidra J.H., PhD, Freeman, Brian M., MD, Kirkpatrick, Stacy S., BS, Beddies, John W., MD, Arnold, Joshua D., MD, Freeman, Michael B., MD, Goldman, Mitchell H., MD, Stevens, Scott L., MD, Klein, Frederick A., MD, Grandas, Oscar H., MD

“…Abstract Background Testosterone deficiency has been associated with an increased risk of vascular disease. Matrix metalloproteinases (MMPs) have been…”
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Systemic hypersensitivity reaction to endovascular stainless steel stent by Univers, Junior, Long, Chandler, Tonks, Stephen A., Freeman, Michael B.

“…Endovascular intervention has become the mainstay for treatment of most patients suffering from peripheral vascular disease. We describe a patient with a known…”
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Serum Levels of Matrix Metalloproteinase-2 as a Marker of Intimal Hyperplasia by Tummers, A. Mike, M.D, Mountain, Deidra J.H., Ph.D, Mix, J. William, M.D, Kirkpatrick, Stacy S., B.S, Cassada, David C., M.D, Stevens, Scott L., M.D, Freeman, Michael B., M.D, Goldman, Mitchell H., M.D, Grandas, Oscar H., M.D

“…Background A primary component in the development of intimal hyperplasia (IH) in response to vascular injury is basement membrane remodeling. Matrix…”
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Low testosterone elevates interleukin family cytokines in a rodent model: a possible mechanism for the potentiation of vascular disease in androgen-deficient males by Freeman, Brian M., MD, Mountain, Deidra J.H., PhD, Brock, Timothy C., MD, Chapman, Jason R., MD, Kirkpatrick, Stacy S., BS, Freeman, Michael B., MD, Klein, Frederick A., MD, Grandas, Oscar H., MD

“…Abstract Background Androgen deficiency (AD) is associated with increased risk of atherosclerosis, cardiovascular, and peripheral arterial disease. Although…”
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Smooth muscle cell polymeric transfection is an efficient alternative to traditional methods of experimental gene therapy by Arnold, Joshua D., MD, Mountain, Deidra J.H., PhD, Freeman, Michael B., MD, Kirkpatrick, Stacy S., BS, Stevens, Scott L., MD, Goldman, Mitchell H., MD, Grandas, Oscar H., MD

“…Abstract Background Gene therapy shows promise in the treatment of vascular disease. However, traditional transfection methods commonly used in the laboratory…”
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Phenology of Douglas-Fir Beetle (Coleoptera: Curculionidae) and Its Role in Douglas-Fir Mortality in Western Washington by Freeman, Michael B, LaBarge, Amy, Tobin, Patrick C

“…Douglas-fir dominated forests are an integral part of the Pacific Northwest. In the Cedar River Municipal Watershed, Washington, these forests provide erosion…”
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Effect of Hormones on Matrix Metalloproteinases Gene Regulation in Human Aortic Smooth Muscle Cells by Grandas, Oscar H., M.D, Mountain, Deidra J.H., Ph.D, Kirkpatrick, Stacy S., B.S, Rudrapatna, Vivek S., M.D, Cassada, David C., M.D, Stevens, Scott L., M.D, Freeman, Michael B., M.D, Goldman, Mitchell H., M.D

“…Background Postmenopausal women receiving hormone replacement therapy have more adverse outcomes after vascular reconstructions. Estrogen-binding receptors…”
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The importance of thrombophilia in the treatment of Paget-Schroetter syndrome by Cassada, David C, Lipscomb, Amy L, Stevens, Scott L, Freeman, Michael B, Grandas, Oscar H, Goldman, Mitchell H

“…Venous thoracic outlet syndrome (V-TOS) and associated subclavian vein thrombosis (SVT) result in significant patient morbidity and can be difficult to manage…”
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Development and Validation of the Rapid Estimate of Adult Literacy in Vascular Surgery (REAL_VS) by Wallace, Lorraine S., PhD, Ergen, William F., M1, Cassada, David C., MD, Freeman, Michael B., MD, Grandas, Oscar H., MD, Stevens, Scott L., MD, Goldman, Mitchell H., MD

“…The purposes of this study were to develop and validate the (1) Rapid Estimate of Adult Literacy in Vascular Surgery (REAL_VS) for researchers studying the…”
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Emotional Intelligence and Burnout Related to Resident-Assessed Faculty Teaching Scores by Lewis, James M, Yared, Katherine, Heidel, Robert E, Kirkpatrick, Baileigh, Freeman, Michael B., Daley, Brian J, Shatzer, John, McCallum, R Steve

“…Emotional intelligence (EI) is associated with job success in multiple fields, in part, because EI may mitigate stress and burnout. Research suggests these…”
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Improving the efficacy of liposome-mediated vascular gene therapy via lipid surface modifications by Fisher, Richard K., Mattern-Schain, Samuel I., Best, Michael D., Kirkpatrick, Stacy S., Freeman, Michael B., Grandas, Oscar H., Mountain, Deidra J.H.

“…We have previously defined mechanisms of intimal hyperplasia that could be targets for molecular therapeutics aimed at vascular pathology. However,…”
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