Search Results - "Freeling, P"

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence by Freeling, Jennifer P, Ho, Rodney J Y

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Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems by Kraft, John C, Freeling, Jennifer P, Wang, Ziyao, Ho, Rodney J Y

“…Liposomes are spherical-enclosed membrane vesicles mainly constructed with lipids. Lipid nanoparticles are loaded with therapeutics and may not contain an…”
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Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood by Freeling, Jennifer P, Koehn, Josefin, Shu, Cuiling, Sun, Jianguo, Ho, Rodney J Y

“…Insufficient HIV drug levels in lymph nodes have been linked to viral persistence. To overcome lymphatic drug insufficiency, we developed and evaluated in…”
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Anti-HIV drug-combination nanoparticles enhance plasma drug exposure duration as well as triple-drug combination levels in cells within lymph nodes and blood in primates by Freeling, Jennifer P, Koehn, Josefin, Shu, Cuiling, Sun, Jianguo, Ho, Rodney J Y

“…HIV patients on combination oral drug therapy experience insufficient drug levels in lymph nodes, which is linked to viral persistence. Following success in…”
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Evaluation of atazanavir and darunavir interactions with lipids for developing pH-responsive anti-HIV drug combination nanoparticles by Duan, Jinghua, Freeling, Jennifer P, Koehn, Josefin, Shu, Cuiling, Ho, Rodney J Y

“…We evaluated two human immunodeficiency virus (HIV) protease inhibitors, atazanavir (ATV) and darunavir (DRV), for pH-dependent solubility, lipid binding, and…”
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Telephone versus postal surveys of general practitioners: methodological considerations by Sibbald, B, Addington-Hall, J, Brenneman, D, Freeling, P

“…High response rates to surveys help to maintain the representativeness of the sample. In the course of a wider investigation into counselling services within…”
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Antiretroviral nanoparticles: the future is now: authors' response to editorial comments by Freeling, Jennifer P, Ho, Rodney J Y

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Impact of a national campaign on GP education: an evaluation of the Defeat Depression Campaign by Rix, S, Paykel, E S, Lelliott, P, Tylee, A, Freeling, P, Gask, L, Hart, D

“…The Defeat Depression Campaign, which was run by the Royal College of Psychiatrists and the Royal College of General Practitioners (RCGP) from 1992 to 1996,…”
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How does the content of consultations affect the recognition by general practitioners of major depression in women? by Tylee, A, Freeling, P, Kerry, S, Burns, T

“…Major depression is a common and disabling condition. However, for many reasons, the condition is not recognized in about half of the patients with major…”
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Randomised controlled trial of effects of coordinating care for terminally ill cancer patients by Addington-Hall, J. M., MacDonald, L. D., Anderson, H. R., Chamberlain, J., Freeling, P., Bland, J. M., Raftery, J.

“…OBJECTIVES--To measure effects on terminally ill cancer patients and their families of coordinating the services available within the NHS and from local…”
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Provision of care to general practice patients with disabling long-term mental illness: a survey in 16 practices by Kendrick, T, Burns, T, Freeling, P, Sibbald, B

“…Increasing numbers of long-term mentally ill people now live in the community, many of whom lose contact with psychiatric services and come to depend on…”
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Diagnosis and treatment of depression in general practice by Freeling, P

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Predictors of therapeutic benefit from amitriptyline in mild depression: a general practice placebo-controlled trial by Paykel, E S, Hollyman, J A, Freeling, P, Sedgwick, P

“…General practice depressives were treated for 6 weeks with amitriptyline or placebo in a controlled trial. Overall, drug was found strongly superior to…”
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Why do general practitioners recognize major depression in one woman patient yet miss it in another? by Tylee, A T, Freeling, P, Kerry, S

“…The aim of this study was to establish whether psychiatric patient characteristics and the presence of physical illness affected general practitioners'…”
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Systems Approach to targeted and long-acting HIV/AIDS therapy by Ho, Rodney J. Y., Yu, Jesse, Li, Bowen, Kraft, John C., Freeling, Jennifer P., Koehn, Josefin, Shao, Jingwei

“…Medication adherence and insufficient drug levels are central to HIV/AIDS disease progression. Recently, Fletcher et al. confirmed that HIV patients on oral…”
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A randomized controlled trial of the cost-effectiveness of a district co-ordinating service for terminally ill cancer patients by Raftery, J P, Addington-Hall, J M, MacDonald, L D, Anderson, H R, Bland, J M, Chamberlain, J, Freeling, P

“…The objective of this paper is to compare the cost effectiveness of a co-ordination service with standard services for terminally ill cancer patients with a…”
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Role of general practitioners in care of long term mentally ill patients by Kendrick, T, Sibbald, B, Burns, T, Freeling, P

“…OBJECTIVE--To assess general practitioners' involvement with long term mentally ill patients and attitudes towards their care. DESIGN--Postal questionnaire…”
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The Sir David Bruce Lecture, 1994: A Matter of Principles by Freeling, P

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Efficacy of cod liver oil as an adjunct to non-steroidal anti-inflammatory drug treatment in the management of osteoarthritis in general practice by Stammers, T, Sibbald, B, Freeling, P

“…A double blind, placebo controlled trial was carried out to assess the efficacy of cod liver oil as an adjunct treatment to non-steroidal anti-inflammatory…”
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A communication skills course for preclinical students: evaluation of general practice based teaching using group methods by Kendrick, T, Freeling, P

“…Teaching preclinical medical students about doctor-patient communication gives them an opportunity to develop their interviewing skills prior to their having…”
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