Search Results - "Freedman, Jonathan D"

A Mechanistic Study of Wetting Superhydrophobic Porous 3D Meshes by Yohe, Stefan T., Freedman, Jonathan D., Falde, Eric J., Colson, Yolonda L., Grinstaff, Mark W.

“…Superhydrophobic, porous, 3D materials composed of poly(ϵ‐caprolactone) (PCL) and the hydrophobic polymer dopant poly(glycerol monostearate‐co‐ϵ‐caprolactone)…”
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Contrast-enhanced CT using a cationic contrast agent enables non-destructive assessment of the biochemical and biomechanical properties of mouse tibial plateau cartilage by Lakin, Benjamin A., Patel, Harsh, Holland, Conor, Freedman, Jonathan D., Shelofsky, Joshua S., Snyder, Brian D., Stok, Kathryn S., Grinstaff, Mark W.

“…ABSTRACT Mouse models of osteoarthritis (OA) are commonly used to study the disease's pathogenesis and efficacy of potential treatments. However, measuring the…”
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The Effect of COVID-19 on Mood Disorders in Urban and Suburban Detroit by Yaphe, Sean, Sundaresan, Lakshmi, Freedman, Jonathan D., Weinberg, Samuel J., Vaughn, Ivana A., Lamerato, Lois E., Budzynska, Katarzyna

“…•State of Michigan COVID-19 lockdown began on March 23, 2020.•This is a retrospective study of December 2018–June 2021 administrative data from a large…”
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Repair of an Occipital Meningocele and Scalp Soft-tissue Reconstruction in a Newborn Patient by Freedman, Jonathan D, Gehring, Michael B, O'Neill, Brent R, French, Brooke, Khechoyan, David

“…The differential diagnosis of large congenital scalp defects includes aplasia cutis and encephalocele, among others. Treatment includes conservative management…”
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Intraoperative Anaphylaxis to Gelatin during Alveolar Bone Grafting for Cleft Palate by Gehring, Michael B, Freedman, Jonathan D, Wolfe, Brandon, French, Brooke M, Khechoyan, David Y

“…Intraoperative anaphylaxis can be life threatening. Anaphylaxis to gelatin-based topical hemostatic agents is an underrecognized hypersensitivity. To date,…”
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What a Ratchet! A Gripping Case Report of an Entrapped Finger with an Unyielding Wrench by Freedman, Jonathan D, Aglio, 3rd, James J, Philippe-Auguste, Michael, Slavin, Blaire V, Coelho, Paulo G, Tadisina, Kashyap K, Xu, Kyle Y, Panthaki, Zubin J

“…Finger entrapment with rings or ring-like objects is an uncommon possible hand emergency. In cases in which noncutting removal is ineffective, ring cutters or…”
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Prevention of lung cancer recurrence using cisplatin-loaded superhydrophobic nanofiber meshes by Kaplan, Jonah A, Liu, Rong, Freedman, Jonathan D, Padera, Robert, Schwartz, John, Colson, Yolonda L, Grinstaff, Mark W

“…Abstract For early stage lung cancer patients, local cancer recurrence after surgical resection is a significant concern and stems from microscopic disease…”
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Bone-Crack Detection, Targeting, and Repair Using Ion Gradients by Yadav, Vinita, Freedman, Jonathan D., Grinstaff, Mark, Sen, Ayusman

“…Bone cracks can be detected by utilizing the damaged matrix itself as both the trigger and the fuel. A crack in a material with a high mineral content such as…”
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Tantalum Oxide Nanoparticles for the Imaging of Articular Cartilage Using X-Ray Computed Tomography: Visualization of Ex Vivo/In Vivo Murine Tibia and Ex Vivo Human Index Finger Cartilage by Freedman, Jonathan D., Lusic, Hrvoje, Snyder, Brian D., Grinstaff, Mark W.

“…The synthesis and characterization of tantalum oxide (Ta2O5) nanoparticles (NPs) as new X‐ray contrast media for microcomputed tomography (μCT) imaging of…”
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Synthesis and Preclinical Characterization of a Cationic Iodinated Imaging Contrast Agent (CA4+) and Its Use for Quantitative Computed Tomography of Ex Vivo Human Hip Cartilage by Stewart, Rachel C, Patwa, Amit N, Lusic, Hrvoje, Freedman, Jonathan D, Wathier, Michel, Snyder, Brian D, Guermazi, Ali, Grinstaff, Mark W

“…Contrast agents that go beyond qualitative visualization and enable quantitative assessments of functional tissue performance represent the next generation of…”
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Layered superhydrophobic meshes for controlled drug release by Falde, Eric J., Freedman, Jonathan D., Herrera, Victoria L.M., Yohe, Stefan T., Colson, Yolonda L., Grinstaff, Mark W.

“…Layered superhydrophobic electrospun meshes composed of poly(ε-caprolactone) (PCL) and poly(glycerol monostearate-co-ε-caprolactone) (PGC-C18) are described as…”
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Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast‐enhanced μCT by Mashiatulla, Maleeha, Moran, Meghan M., Chan, Deva, Li, Jun, Freedman, Jonathan D., Snyder, Brian D., Grinstaff, Mark W., Plaas, Anna, Sumner, Dale R.

“…ABSTRACT Articular cartilage lines the load‐bearing surfaces of long bones and undergoes compositional and structural degeneration during osteoarthritis…”
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A cationic gadolinium contrast agent for magnetic resonance imaging of cartilage by Freedman, Jonathan D, Lusic, Hrvoje, Wiewiorski, Martin, Farley, Michelle, Snyder, Brian D, Grinstaff, Mark W

“…A new cationic gadolinium contrast agent is reported for delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC). The agent partitions…”
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dGEMRIC and CECT Comparison of Cationic and Anionic Contrast Agents in Cadaveric Human Metacarpal Cartilage by Freedman, Jonathan D., Ellis, Daniel J., Lusic, Hrvoje, Varma, Gopal, Grant, Aaron K., Lakin, Benjamin A., Snyder, Brian D., Grinstaff, Mark W.

“…ABSTRACT Magnetic resonance imaging (MRI) and computed tomography (CT) are widely used to image cartilage and their diagnostic capability is enhanced in the…”
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Contrast‐Enhanced Computed Tomography Scoring System for Distinguishing Early Osteoarthritis Disease States: A Feasibility Study by Stewart, Rachel C., Nelson, Brad B., Kawcak, Chris E., Freedman, Jonathan D., Snyder, Brian D., Goodrich, Laurie R., Grinstaff, Mark W.

“…ABSTRACT Early detection of osteoarthritis (OA) remains a diagnostic challenge owing to insensitive diagnostic techniques currently available. Herein a new…”
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Bilateral Distal Radius Fractures in a Patient with Osteogenesis Imperfecta: A Case Report by Freedman, Jonathan D., Merkle, Alexander N., Iorio, Matthew L.

“…Longitudinal follow-up of a 53-year-old woman with osteogenesis imperfecta (OI) Type III and concurrent bilateral distal radius fractures is reported. She had…”
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Contrast‐enhanced CT imaging as a non‐destructive tool for ex vivo examination of the biochemical content and structure of the human meniscus by Oh, Daniel J., Lakin, Benjamin A., Stewart, Rachel C., Wiewiorski, Martin, Freedman, Jonathan D., Grinstaff, Mark W., Snyder, Brian D.

“…ABSTRACT The biochemical and histopathological techniques used to investigate meniscal content and structure are destructive and time‐consuming. Therefore,…”
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Contrast enhanced CT attenuation correlates with the GAG content of bovine meniscus by Lakin, Bejamin A., Grasso, Daniel J., Stewart, Rachel C., Freedman, Jonathan D., Snyder, Brian D., Grinstaff, Mark W.

“…ABSTRACT We determined whether contrast‐enhanced computed tomography (CECT) attenuation obtained using a µCT scanner correlated with the glycosaminoglycan…”
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Cationic Contrast Agent Diffusion Differs Between Cartilage and Meniscus by Honkanen, Juuso T. J., Turunen, Mikael J., Freedman, Jonathan D., Saarakkala, Simo, Grinstaff, Mark W., Ylärinne, Janne H., Jurvelin, Jukka S., Töyräs, Juha

“…Contrast enhanced computed tomography (CECT) is a non-destructive imaging technique used for the assessment of composition and structure of articular cartilage…”
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Quantitative Evaluation of Equine Articular Cartilage Using Cationic Contrast-Enhanced Computed Tomography by Nelson, Brad B., Stewart, Rachel C., Kawcak, Chris E., Freedman, Jonathan D., Patwa, Amit N., Snyder, Brian D., Goodrich, Laurie R., Grinstaff, Mark W.

“…Objective To investigate the diffusion trajectory of a cationic contrast medium (CA4+) into equine articular cartilage, and to assess normal and degenerative…”
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