Search Results - "Fredrik Elinder"

The Molecular Basis of Polyunsaturated Fatty Acid Interactions with the Shaker Voltage-Gated Potassium Channel by Yazdi, Samira, Stein, Matthias, Elinder, Fredrik, Andersson, Magnus, Lindahl, Erik

“…Voltage-gated potassium (KV) channels are membrane proteins that respond to changes in membrane potential by enabling K+ ion flux across the membrane…”
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A quantitative analysis of cell-specific contributions and the role of anesthetics to the neurovascular coupling by Sten, Sebastian, Elinder, Fredrik, Cedersund, Gunnar, Engström, Maria

“…The neurovascular coupling (NVC) connects neuronal activity to hemodynamic responses in the brain. This connection is the basis for the interpretation of…”
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A quantitative model for human neurovascular coupling with translated mechanisms from animals by Sten, Sebastian, Podéus, Henrik, Sundqvist, Nicolas, Elinder, Fredrik, Engström, Maria, Cedersund, Gunnar

“…Neurons regulate the activity of blood vessels through the neurovascular coupling (NVC). A detailed understanding of the NVC is critical for understanding data…”
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An electrostatic potassium channel opener targeting the final voltage sensor transition by Börjesson, Sara I, Elinder, Fredrik

“…Free polyunsaturated fatty acids (PUFAs) modulate the voltage dependence of voltage-gated ion channels. As an important consequence thereof, PUFAs can suppress…”
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Tracking a complete voltage-sensor cycle with metal-ion bridges by Henrion, Ulrike, Renhorn, Jakob, Börjesson, Sara I, Nelson, Erin M, Schwaiger, Christine S, Bjelkmar, Pär, Wallner, Björn, Lindahl, Erik, Elinder, Fredrik

“…Voltage-gated ion channels open and close in response to changes in membrane potential, thereby enabling electrical signaling in excitable cells. The voltage…”
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Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel by Liin, Sara I, Silverå Ejneby, Malin, Barro-Soria, Rene, Skarsfeldt, Mark Alexander, Larsson, Johan E, Starck Härlin, Frida, Parkkari, Teija, Bentzen, Bo Hjorth, Schmitt, Nicole, Larsson, H Peter, Elinder, Fredrik

“…Polyunsaturated fatty acids (PUFAs) affect cardiac excitability. Kv7.1 and the β-subunit KCNE1 form the cardiac IKs channel that is central for cardiac…”
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Structure, Function, and Modification of the Voltage Sensor in Voltage-Gated Ion Channels by Börjesson, Sara I., Elinder, Fredrik

“…Voltage-gated ion channels are crucial for both neuronal and cardiac excitability. Decades of research have begun to unravel the intriguing machinery behind…”
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Drug-induced ion channel opening tuned by the voltage sensor charge profile by Ottosson, Nina E, Liin, Sara I, Elinder, Fredrik

“…Polyunsaturated fatty acids modulate the voltage dependence of several voltage-gated ion channels, thereby being potent modifiers of cellular excitability…”
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Functionalised ZnO-nanorod-based selective electrochemical sensor for intracellular glucose by Asif, Muhammad H., Ali, Syed M. Usman, Nur, Omer, Willander, Magnus, Brännmark, Cecilia, Strålfors, Peter, Englund, Ulrika H., Elinder, Fredrik, Danielsson, Bengt

“…In this article, we report a functionalised ZnO-nanorod-based selective electrochemical sensor for intracellular glucose. To adjust the sensor for…”
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Mechanistic Mathematical Modeling Tests Hypotheses of the Neurovascular Coupling in fMRI by Lundengård, Karin, Cedersund, Gunnar, Sten, Sebastian, Leong, Felix, Smedberg, Alexander, Elinder, Fredrik, Engström, Maria

“…Functional magnetic resonance imaging (fMRI) measures brain activity by detecting the blood-oxygen-level dependent (BOLD) response to neural activity. The BOLD…”
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Lipoelectric Modification of Ion Channel Voltage Gating by Polyunsaturated Fatty Acids by Börjesson, Sara I., Hammarström, Sven, Elinder, Fredrik

“…Polyunsaturated fatty acids (PUFAs) have beneficial effects on epileptic seizures and cardiac arrhythmia. We report that ω-3 and ω-6 all-cis-PUFAs affected the…”
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Perceptions of Overuse Injury Among Swedish Ultramarathon and Marathon Runners: Cross-Sectional Study Based on the Illness Perception Questionnaire Revised (IPQ-R) by Wickström, William, Spreco, Armin, Bargoria, Victor, Elinder, Fredrik, Hansson, Per-Olof, Dahlström, Örjan, Timpka, Toomas

“…Long-distance runners' understandings of overuse injuries are not well known which decreases the possibilities for prevention. The common sense model (CSM)…”
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Electrostatic Tuning of Cellular Excitability by Börjesson, Sara I., Parkkari, Teija, Hammarström, Sven, Elinder, Fredrik

“…Voltage-gated ion channels regulate the electric activity of excitable tissues, such as the heart and brain. Therefore, treatment for conditions of disturbed…”
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A voltage dependent non-inactivating Na+ channel activated during apoptosis in Xenopus oocytes by Englund, Ulrika H, Gertow, Jens, Kågedal, Katarina, Elinder, Fredrik

“…Ion channels in the plasma membrane are important for the apoptotic process. Different types of voltage-gated ion channels are up-regulated early in the…”
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Potassium channel openers targeting different sites of the channel by Elinder, Fredrik

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Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acids acting on voltage-gated ion channels by Tigerholm, Jenny, Börjesson, Sara I, Lundberg, Linnea, Elinder, Fredrik, Fransén, Erik

“…A ketogenic diet is an alternative treatment of epilepsy in infants. The diet, rich in fat and low in carbohydrates, elevates the level of polyunsaturated…”
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Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells by Akanda, Nesar, Tofighi, Roshan, Brask, Johan, Tamm, Christoffer, Elinder, Fredrik, Ceccatelli, Sandra

“…microRNAs (miRNAs) are small non-coding RNAs that regulate a large variety of cellular processes including differentiation, apoptosis and proliferation…”
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Biophysical Properties of the Apoptosis-Inducing Plasma Membrane Voltage-Dependent Anion Channel by Akanda, Nesar, Elinder, Fredrik

“…Ion channels in the plasma membrane play critical roles in apoptosis. In a recent study we found that a voltage-dependent anion channel in the plasma membrane…”
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The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain by Schwaiger, Christine S, Börjesson, Sara I, Hess, Berk, Wallner, Björn, Elinder, Fredrik, Lindahl, Erik

“…The gating of voltage-gated ion channels is controlled by the arginine-rich S4 helix of the voltage-sensor domain moving in response to an external potential…”
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Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels by Elinder, Fredrik, Männikkö, Roope, Pandey, Shilpi, Larsson, H. Peter

“…Hyperpolarization-activated, cyclic-nucleotide-gated (HCN) channels regulate pacemaker activity in the heart and the brain. Previously, we showed that spHCN…”
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