Search Results - "Frederix, Geert W J"
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Low dose cisplatin weekly versus high dose cisplatin every three weeks in primary chemoradiotherapy in head and neck cancer patients with low skeletal muscle mass: The CISLOW-study protocol
Published in PloS one (27-11-2023)“…Chemoradiotherapy with cisplatin in a triweekly regimen of 100 mg/m2 body surface area, is used to treat locally advanced head and neck squamous cell carcinoma…”
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Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE)
Published in BMC medical genomics (10-11-2020)“…'Precision oncology' can ensure the best suitable treatment at the right time by tailoring treatment towards individual patient and comprehensive tumour…”
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Cost-effectiveness of the implementation of [68Ga]Ga-PSMA-11 PET/CT at initial prostate cancer staging
Published in Insights into imaging (13-08-2022)“…Background Despite its high specificity, PSMA PET/CT has a moderate to low sensitivity of 40–50% for pelvic lymph node detection, implicating that a negative…”
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A cost-utility analysis of cochlear implants for single sided deafness in adults and children in the Netherlands
Published in PloS one (05-08-2024)“…Cochlear Implant (CI) has been shown to improve speech comprehension, sound localization and tinnitus in adults with Single-Sided-Deafness (SSD) compared to…”
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Effectiveness of endoscopic totally extraperitoneal (TEP) hernia correction for clinically occult inguinal hernia (EFFECT): study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (18-06-2018)“…Groin pain is a frequent complaint in surgical practice with an inguinal hernia being at the top of the differential diagnosis. The majority of inguinal…”
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Development of a clinical prediction rule for sepsis in primary care: protocol for the TeSD-IT study
Published in Diagnostic and prognostic research (06-08-2020)“…Early recognition and treatment of sepsis is crucial to prevent detrimental outcomes. General practitioners (GPs) are often the first healthcare providers to…”
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Check Your Checklist: The Danger of Over- and Underestimating the Quality of Economic Evaluations
Published in PharmacoEconomics - open (01-12-2019)“…[...]using the Drummond checklist for appraising modelling studies will lead to an incomplete quality assessment as the focus of this checklist is on reporting…”
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Cost-effectiveness of Laparoscopic vs Open Gastrectomy for Gastric Cancer: An Economic Evaluation Alongside a Randomized Clinical Trial
Published in JAMA surgery (01-02-2023)“…Laparoscopic gastrectomy is rapidly being adopted worldwide as an alternative to open gastrectomy to treat gastric cancer. However, laparoscopic gastrectomy…”
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Dual hormone fully closed loop in type 1 diabetes: a randomised trial in the Netherlands – study protocol
Published in BMJ open (23-08-2023)“…Introduction The management of type 1 diabetes (T1DM) has undergone significant advancements with the availability of novel technologies, notably continuous…”
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RELEASE-HF study: a protocol for an observational, registry-based study on the effectiveness of telemedicine in heart failure in the Netherlands
Published in BMJ open (04-01-2024)“…IntroductionMeta-analyses show postive effects of telemedicine in heart failure (HF) management on hospitalisation, mortality and costs. However, these effects…”
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Diagnostic accuracy of Ara h 2 for detecting peanut allergy in children
Published in Clinical and experimental allergy (01-08-2021)“…Background Specific IgE to Ara h 2 is a diagnostic test for peanut allergy which may reduce the need for double‐blind placebo‐controlled food challenges…”
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Unremarked or Unperformed? Systematic Review on Reporting of Validation Efforts of Health Economic Decision Models in Seasonal Influenza and Early Breast Cancer
Published in PharmacoEconomics (01-09-2016)“…Background Transparent reporting of validation efforts of health economic models give stakeholders better insight into the credibility of model outcomes. In…”
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Managing the Increasing Burden of Atrial Fibrillation through Integrated Care in Primary Care: A Cost-Effectiveness Analysis
Published in International journal of integrated care (01-04-2023)“…Integrated care for patients with atrial fibrillation (AF) in primary care reduced mortality compared to usual care. We assessed the cost-effectiveness of this…”
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Costs Associated With Timely and Delayed Surgical Treatment of Spinal Metastases
Published in Global spine journal (01-10-2022)“…Study Design: Retrospective cohort study. Objectives: Symptoms caused by spinal metastases are often difficult to distinguish from symptoms caused by…”
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Protocol of a multicentre, prospective cohort study that evaluates cost-effectiveness of two perioperative care strategies for potential obstructive sleep apnoea in morbidly obese patients undergoing bariatric surgery
Published in BMJ open (07-10-2020)“…IntroductionDespite the high prevalence of obstructive sleep apnoea (OSA) in obese patients undergoing bariatric surgery, OSA is undiagnosed in the majority of…”
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Economic and cost-effectiveness analysis of the Community-Level Interventions for Pre-eclampsia (CLIP) trials in India, Pakistan and Mozambique
Published in BMJ global health (01-05-2021)“…BackgroundThe Community-Level Interventions for Pre-eclampsia (CLIP) trials (NCT01911494) in India, Pakistan and Mozambique (February 2014–2017) involved…”
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Potential impact of a new sepsis prediction model for the primary care setting: early health economic evaluation using an observational cohort
Published in BMJ open (17-01-2024)“…ObjectivesTo estimate the potential referral rate and cost impact at different cut-off points of a recently developed sepsis prediction model for general…”
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Advanced image-supported lead placement in cardiac resynchronisation therapy: protocol for the multicentre, randomised controlled ADVISE trial and early economic evaluation
Published in BMJ open (25-10-2021)“…IntroductionAchieving optimal placement of the left ventricular (LV) lead in cardiac resynchronisation therapy (CRT) is a prerequisite in order to achieve…”
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DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis
Published in The lancet oncology (01-11-2018)“…Fluoropyrimidine treatment can result in severe toxicity in up to 30% of patients and is often the result of reduced activity of the key metabolic enzyme…”
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Diagnostic Yield of Next Generation Sequencing in Genetically Undiagnosed Patients with Primary Immunodeficiencies: a Systematic Review
Published in Journal of clinical immunology (01-08-2019)“…Background As the application of next generation sequencing (NGS) is moving to earlier stages in the diagnostic pipeline for primary immunodeficiencies (PIDs),…”
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