Search Results - "Frederiksen, K. S."
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A European Academy of Neurology guideline on medical management issues in dementia
Published in European journal of neurology (01-10-2020)“…© 2020 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. Background and purpose:…”
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The foreland-propagating thrust architecture of the East Greenland Caledonides 72°-75°N
Published in Journal of the Geological Society (01-11-2004)“…Systematic geological mapping of the East Greenland Caledonides demonstrates that the orogen is built up of WNW-directed thrust sheets displaced across…”
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Identification of hepatic transcriptional changes in insulin-resistant rats treated with peroxisome proliferator activated receptor-alpha agonists
Published in Journal of molecular endocrinology (01-06-2003)“…Peroxisome proliferator activated receptor (PPAR)-alpha controls the expression of multiple genes involved in lipid metabolism, and activators of PPAR-alpha,…”
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Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene : evaluation of their relation with alterations in insulin secretion and insulin sensitivity
Published in Diabetologia (01-10-1999)“…The aim of this study was to screen part of the putative promoter sequence in addition to 14 potential phosphotyrosine residues of human IRS-2 for genetic…”
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Physical activity in the elderly is associated with improved executive function and processing speed: the LADIS Study
Published in International journal of geriatric psychiatry (01-07-2015)“…Objectives Physical activity reduces the risk of cognitive decline but may affect cognitive domains differently. We examined whether physical activity modifies…”
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Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance
Published in Diabetologia (01-08-1998)“…The family of insulin receptor substrates (IRS1-4) is defined by proteins with an overall similar structure. IRS-1 and IRS-2 have been shown to have key roles…”
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Sequential architecture and cyclicity in Permian desert deposits, Brodick Beds, Arran, Scotland
Published in Journal of the Geological Society (01-07-1998)“…This study of ancient desert deposits (Permian Brodick Beds) tests the possibility that cyclicityin these interbedded aeolian, fluvial and lacustrine deposits…”
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Zinc Oxide Inhibits Axillary Colonization by Members of the Genus Corynebacterium and Attenuates Self-perceived Malodour: A Randomized, Double-blind, Placebo-controlled Trial
Published in Acta dermato-venereologica (28-05-2020)“…Malodour from the axilla is commonly caused by specific microbes, and may be inhibited by zinc oxide. The aim of this study was to determine the effects of…”
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Gene therapy for lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-03-1999)“…In the pre-clinical research into the development of gene therapy for cancer, different strategies have evolved and shown promising results in the laboratory…”
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Genome-wide association study on cerebral white-matter hyperintensities in 36,577 individuals
Published in European heart journal (03-10-2022)“…Abstract Background/Introduction A quarter of all strokes are caused by cerebral small vessel disease (CSVD), which is also the most common pathology…”
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Left atrial remodeling and cerebrovascular disease assessed by magnetic resonance imaging in patients undergoing continuous heart rhythm monitoring
Published in European heart journal (12-10-2021)“…Abstract Background Atrial remodeling and atrial fibrillation (AF) have both been associated with cerebrovascular lesions. We wished to investigate the…”
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Gene delivery by an epidermal growth factor/DNA polyplex to small cell lung cancer cell lines expressing low levels of epidermal growth factor receptor
Published in Cancer gene therapy (01-02-2000)“…In the present study, we wanted to determine whether efficient gene delivery using an epidermal growth factor (EGF)/DNA polyplex could be accomplished in small…”
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Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes
Published in Nature communications (20-08-2021)“…Histone lysine methylations have primarily been linked to selective recruitment of reader or effector proteins that subsequently modify chromatin regions and…”
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The impact of the COVID-19 pandemic on mortality in people with dementia without COVID-19: a systematic review and meta-analysis
Published in BMC geriatrics (19-11-2022)“…Significant mortality amongst vulnerable populations, such as people living with dementia, might go undetected during pandemic conditions due to refocus of…”
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European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders
Published in Lancet neurology (01-03-2024)“…The recent commercialisation of the first disease-modifying drugs for Alzheimer's disease emphasises the need for consensus recommendations on the rational use…”
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European Academy of Neurology/European Alzheimer’s Disease Consortium position statement on diagnostic disclosure, biomarker counseling, and management of patients with mild cognitive impairment
Published in European journal of neurology (01-07-2021)“…Background and purpose Careful counseling through the diagnostic process and adequate postdiagnostic support in patients with mild cognitive impairment (MCI)…”
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The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity
Published in Alzheimer's & dementia (01-02-2015)“…Abstract Background An international Delphi panel has defined a harmonized protocol (HarP) for the manual segmentation of the hippocampus on MR. The aim of…”
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European consensus for the diagnosis of MCI and mild dementia: Preparatory phase
Published in Alzheimer's & dementia (01-05-2023)“…Introduction Etiological diagnosis of neurocognitive disorders of middle‐old age relies on biomarkers, although evidence for their rational use is incomplete…”
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Biomarker counseling, disclosure of diagnosis and follow‐up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey
Published in International journal of geriatric psychiatry (01-02-2021)“…Objectives Mild cognitive impairment (MCI) is associated with an increased risk of further cognitive decline, partly depending on demographics and biomarker…”
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Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline
Published in European geriatric medicine (2023)“…Background Physical activity and exercise have been suggested as effective interventions for the prevention and management of mild cognitive impairment (MCI)…”
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