Search Results - "Fredericksen, Brenda L"

West Nile virus (WNV) replication is independent of autophagy in mammalian cells by Vandergaast, Rianna, Fredericksen, Brenda L

“…Autophagy is a homeostatic process responsible for recycling cytosolic proteins and organelles. Moreover, this pathway contributes to the cell's intrinsic…”
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Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1 by FREDERICKSEN, Brenda L, KELLER, Brian C, FORNEK, Jamie, KATZE, Michael G, GALE, Michael

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Differential induction of CCL5 by pathogenic and non-pathogenic strains of West Nile virus in brain endothelial cells and astrocytes by Hussmann, Katherine L, Fredericksen, Brenda L

“…The neuroinflammatory response to West Nile virus (WNV) infection can be either protective or pathological depending on the context. Although several studies…”
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West Nile Virus Evades Activation of Interferon Regulatory Factor 3 through RIG-I-Dependent and -Independent Pathways without Antagonizing Host Defense Signaling by FREDERICKSEN, Brenda L, GALE, Michael

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Differential Replication of Pathogenic and Nonpathogenic Strains of West Nile Virus within Astrocytes by Hussmann, Katherine L, Samuel, Melanie A, Kim, Kwang S, Diamond, Michael S, Fredericksen, Brenda L

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Resistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and Virulence by KELLER, Brian C, FREDERICKSEN, Brenda L, SAMUEL, Melanie A, MOCK, Richard E, MASON, Peter W, DIAMOND, Michael S, GALE, Michael

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Inhibition of Endosomal/Lysosomal Degradation Increases the Infectivity of Human Immunodeficiency Virus by Fredericksen, Brenda L, Wei, Bangdong L, Yao, Jian, Luo, Tianci, Garcia, J Victor

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The Host Response to West Nile Virus Infection Limits Viral Spread through the Activation of the Interferon Regulatory Factor 3 Pathway by FREDERICKSEN, Brenda L, SMITH, Maria, KATZE, Michael G, SHI, Pei-Yong, GALE, Michael JR

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IFN-dependent and -independent reduction in West Nile virus infectivity in human dermal fibroblasts by Hoover, Lisa I, Fredericksen, Brenda L

“…Although dermal fibroblasts are one of the first cell types exposed to West Nile virus (WNV) during a blood meal by an infected mosquito, little is known about…”
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Generation of West Nile virus infectious clones containing amino acid insertions between capsid and capsid anchor by Vandergaast, Rianna, Hoover, Lisa I, Zheng, Kang, Fredericksen, Brenda L

“…West Nile virus (WNV) is a positive-sense RNA arbovirus responsible for recent outbreaks of severe neurological disease within the US and Europe. Large-scale…”
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How flaviviruses activate and suppress the interferon response by Muñoz-Jordán, Jorge L, Fredericksen, Brenda L

“…The flavivirus genus includes viruses with a remarkable ability to produce disease on a large scale. The expansion and increased endemicity of dengue and West…”
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The neuroimmune response to West Nile virus by Fredericksen, Brenda L.

“…The recent introduction of highly pathogenic strains of West Nile virus (WNV) into naïve populations in Europe, Israel, and the USA has resulted in a marked…”
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Generating West Nile Virus from an Infectious Clone by Vandergaast, Rianna, Fredericksen, Brenda L

“…WNV infectious clones are valuable tools for elucidating WNV biology. Nevertheless, relatively few infectious WNV clones have been generated because their…”
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Identification of multiple RIG-I-specific pathogen associated molecular patterns within the West Nile virus genome and antigenome by Shipley, Jennifer German, Vandergaast, Rianna, Deng, Lu, Mariuzza, Roy A, Fredericksen, Brenda L

“…Abstract The ability of viruses to control and/or evade the host antiviral response is critical to the establishment of a productive infection. One of the…”
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Structural proteins of West Nile virus are a major determinant of infectious particle production and fitness in astrocytes by Hussmann, Katherine L, Vandergaast, Rianna, Zheng, Kang, Hoover, Lisa I, Fredericksen, Brenda L

“…The molecular basis for the increased resistance of astrocytes to a non-neuropathogenic strain of West Nile virus (WNV), WNV-MAD78, compared with the…”
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In vitro and in vivo characterization of a West Nile virus MAD78 infectious clone by Hussmann, Katherine L, Vandergaast, Rianna, Ochsner, Susan Park, Huang, Albert C, Gale, Michael, Jr, Fredericksen, Brenda L

“…The viral determinants governing the varied neuropathogenicity of different West Nile virus (WNV) strains are poorly understood. Here, we generated an…”
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Nef: agent of cell subversion by Arora, Vivek K., Fredericksen, Brenda L., Garcia, J.Victor

“…Primate lentiviruses encode a small protein designated Nef that has been shown to be a major determinant of virus pathogenicity. Nef regulates multiple host…”
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Lentivirus Nef Specifically Activates Pak2 by Arora, V K, Molina, R P, Foster, J L, Blakemore, J L, Chernoff, J, Fredericksen, B L, Garcia, J V

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Human Immunodeficiency Virus Type 1 Nef-Induced CD4 Cell Surface Downregulation Is Inhibited by Ikarugamycin by Luo, T, Fredericksen, B L, Hasumi, K, Endo, A, Garcia, J V

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Defining West Nile virus agonists of the RIG-I and MDA5 signaling pathways by Pandit, Sudha, Injaian, Lisa, German, Jennifer, Pankow, Katherine, Fredericksen, Brenda L.

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