Search Results - "Fredericks, Gregory J"

Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex by Fredericks, Gregory J., Hoffmann, FuKun W., Rose, Aaron H., Osterheld, Hanna J., Hess, Franz M., Mercier, Frederic, Hoffmann, Peter R.

“…Significance The stimulation of certain surface receptors on immune cells triggers the release of calcium (Ca ²⁺) stored in the endoplasmic reticulum (ER)…”
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Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis by Meiler, Svenja, Baumer, Yvonne, Huang, Zhi, Hoffmann, Fukun W., Fredericks, Gregory J., Rose, Aaron H., Norton, Robert L., Hoffmann, Peter R., Boisvert, William A.

“…CD36 requires palimitoylation in a selenoprotein K‐dependent manner, to localize lipid rafts and function properly. Selk is an ER transmembrane protein…”
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Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate by Fredericks, Gregory J, Hoffmann, FuKun W, Hondal, Robert J, Rozovsky, Sharon, Urschitz, Johann, Hoffmann, Peter R

“…Selenoprotein K (SELENOK) is a selenocysteine (Sec)-containing protein localized in the endoplasmic reticulum (ER) membrane where it interacts with the DHHC6…”
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Selenoprotein K and protein palmitoylation by Fredericks, Gregory J, Hoffmann, Peter R

“…Selenoprotein K (SelK) is an endoplasmic reticulum (ER) membrane protein, and its expression is sensitive to dietary selenium levels. A recently described role…”
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Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient FcγR‐mediated phagocytosis by Norton, Robert L., Fredericks, Gregory J., Huang, Zhi, Fay, Jeffrey D., Hoffmann, FuKun W., Hoffmann, Peter R.

“…Effective activation of macrophages through phagocytic Fcγ receptors (FcγR) has been shown to require selenoprotein K (Selk). We set out to determine whether…”
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Characterization of the Cortisol Stress Response to Sedation and Anesthesia in Children by Hsu, Angela A, von Elten, Kelley, Chan, Debora, Flynn, Tracy, Walker, Kevin, Barnhill, Jason, Naun, Christopher, Pedersen, Anita M, Ponaman, Michael, Fredericks, Gregory J, Crudo, David F, Pinsker, Jordan E

“…Context: The cortisol stress response to sedation and anesthesia in children is not well characterized. It is not clear whether it is necessary to give stress…”
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A pilot project for improving paediatric diabetes outcomes using a website: the Pediatric Diabetes Education Portal by Pinsker, Jordan E, Nguyen, Charles, Young, Susan, Fredericks, Gregory J, Chan, Debora

“…We created a website for patients and families that allowed them to review clinic test results, review educational materials related to these results and post…”
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Total and Acylated Ghrelin Levels in Children With Poor Growth by Pinsker, Jordan E, Ondrasik, Deborah, Chan, Debora, Fredericks, Gregory J, Tabisola-Nuesca, Eludrizza, Fernandez-Aponte, Minela, Focht, Dean R, Poth, Merrily

“…Ghrelin, an enteric hormone with potent appetite stimulating effects, also stimulates growth hormone release. We hypothesized that altered levels of total…”
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The role of selenoprotein K in DHHC6-mediated protein palmitoylation and the impact on immune cell function by Fredericks, Gregory J

“…This dissertation is a summary of my research which has had one central goal: to discover the function of selenoprotein K (SelK) at the cellular level. Due to…”
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