Search Results - "Freda, P"

Treatment of Pituitary-Dependent Cushing’s Disease with the Multireceptor Ligand Somatostatin Analog Pasireotide (SOM230): A Multicenter, Phase II Trial by Boscaro, M., Ludlam, W. H., Atkinson, B., Glusman, J. E., Petersenn, S., Reincke, M., Snyder, P., Tabarin, A., Biller, B. M. K., Findling, J., Melmed, S., Darby, C. H., Hu, K., Wang, Y., Freda, P. U., Grossman, A. B., Frohman, L. A., Bertherat, J.

“…Context: There is currently no medical therapy for Cushing’s disease that targets the pituitary adenoma. Availability of such a medical therapy would be a…”
Get full text

Ovary Development and Cold Tolerance of the Invasive Pest Drosophila suzukii (Matsumura) in the Central Plains of Kansas, United States by Everman, E. R, Freda, P. J, Brown, M, Schieferecke, A. J, Ragland, G. J, Morgan, T. J

“…Environmental challenges presented by temperature variation can be overcome through phenotypic plasticity in small invasive ectotherms. We tested the effect of…”
Get full text

Pilot study to define criteria for Pituitary Tumors Centers of Excellence (PTCOE): results of an audit of leading international centers by Giustina, A., Uygur, M. M., Frara, S., Barkan, A., Biermasz, N. R., Chanson, P., Freda, P., Gadelha, M., Kaiser, U. B., Lamberts, S., Laws, E., Nachtigall, L. B., Popovic, V., Reincke, M., Strasburger, C., van der Lely, A. J., Wass, J. A. H., Melmed, S., Casanueva, F. F.

“…Purpose The Pituitary Society established the concept and mostly qualitative parameters for defining uniform criteria for Pituitary Tumor Centers of Excellence…”
Get full text

Standards of care for medical management of acromegaly in pituitary tumor centers of excellence (PTCOE) by Giustina, Andrea, Uygur, M. M., Frara, S., Barkan, A., Biermasz, N. R., Chanson, P., Freda, P., Gadelha, M., Haberbosch, L., Kaiser, U. B., Lamberts, S., Laws, E., Nachtigall, L. B., Popovic, V., Reincke, M., van der Lely, A. J., Wass, J. A. H., Melmed, S., Casanueva, F. F.

“…Purpose A series of consensus guidelines on medical treatment of acromegaly have been produced in the last two decades. However, little information is…”
Get full text

Pasireotide Versus Octreotide in Acromegaly: A Head-to-Head Superiority Study by Colao, A, Bronstein, M. D, Freda, P, Gu, F, Shen, C.-C, Gadelha, M, Fleseriu, M, van der Lely, A. J, Farrall, A. J, Hermosillo Reséndiz, K, Ruffin, M, Chen, Y, Sheppard, M

“…Context: Biochemical control reduces morbidity and increases life expectancy in patients with acromegaly. With current medical therapies, including the gold…”
Get full text

Treatment of Acromegaly with the Growth Hormone–Receptor Antagonist Pegvisomant by Trainer, Peter J, Drake, William M, Katznelson, Laurence, Freda, Pamela U, Herman-Bonert, Vivien, van der Lely, A.J, Dimaraki, Eleni V, Stewart, Paul M, Friend, Keith E, Vance, Mary Lee, Besser, G. Michael, Thorner, Michael O, Parkinson, Craig, Klibanski, Anne, Powell, Jeffrey S, Barkan, Ariel L, Sheppard, Michael C, Maldonado, Mario, Rose, D. Roderick, Clemmons, David R, Johannsson, Gudmundur, Bengt-Åke Bengtsson, Bengt-Åke, Stavrou, Stavros, Kleinberg, David L, Cook, David M, Phillips, Lawrence S, Bidlingmaier, Martin, Strasburger, Christian J, Hackett, Suzanne, Zib, Kenneth, Bennett, William F, Davis, Robert J, Scarlett, John A

“…Acromegaly is a chronic debilitating disorder resulting from excessive secretion of growth hormone and a resulting increase in the production of insulin-like…”
Get full text

Evaluation of disease status with sensitive measures of growth hormone secretion in 60 postoperative patients with acromegaly by FREDA, P. U, POST, K. D, POWELL, J. S, WARDLAW, S. L

“…Traditionally, suppression of GH measured by polyclonal RIA to less than 2.0 microg/L after oral glucose was accepted as evidence of remission after…”
Get full text

Differential diagnosis of sellar masses by Freda, P U, Post, K D

“…The differential diagnosis of nonpituitary sellar masses is broad; differentiating among potential etiologies may not always be straightforward because many of…”
Get more information

Long-term endocrinological follow-up evaluation in 115 patients who underwent transsphenoidal surgery for acromegaly by FREDA, P. U, WARDLAW, S. L, POST, K. D

“…The results of surgical therapy for acromegaly were assessed using carefully conducted endocrinological testing in 115 patients who underwent transsphenoidal…”
Get full text

Outcome of radiotherapy for acromegaly using normalization of insulin-like growth factor I to define cure by POWELL, J. S, WARDLAW, S. L, POST, K. D, FREDA, P. U

“…Radiation therapy (RT) has traditionally been considered a useful additional therapy for patients with acromegaly not achieving biochemical remission after…”
Get full text

Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist by van der Lely, Aart Jan, Hutson, R Kent, Trainer, Peter J, Besser, G Michael, Barkan, Ariel L, Katznelson, Laurence, Klibanski, Anne, Herman-Bonert, Vivien, Melmed, Shlomo, Vance, Mary Lee, Freda, Pamela U, Stewart, Paul M, Friend, Keith E, Clemmons, David R, Johannsson, Gudmundur, Stavrou, Stavros, Cook, David M, Phillips, Lawrence S, Strasburger, Christian J, Hacker, Suzanne, Zib, Kenneth A, Davis, Robert J, Scarlett, John A, Thorner, Michael O

“…Pegvisomant is a new growth hormone receptor antagonist that improves symptoms and normalises insulin-like growth factor-1 (IGF-1) in a high proportion of…”
Get full text

Effects of a growth hormone receptor antagonist on bone markers in acromegaly by Fairfield, W. P., Sesmilo, G., Katznelson, L., Pulaski, K., Freda, P. U., Stavrou, S., Kleinberg, D., Klibanski, A.

“…Summary objective Excess GH secretion, as occurs in acromegaly, is associated with abnormalities in bone turnover markers and bone mineral density (BMD). GH…”
Get full text

Unusual causes of sellar/parasellar masses in a large transsphenoidal surgical series by Freda, P U, Wardlaw, S L, Post, K D

Get full text

The clinical spectrum of sarcoglycanopathies by ANGELINI, C, FANIN, M, FREDA, M. P, DUGGAN, D. J, SICILIANO, G, HOFFMAN, E. P

“…A group of 204 muscular dystrophy patients were screened for immunohistochemical and biochemical alpha-sarcoglycan defect and their DNA was analyzed for…”
Get full text

Myocardial involvement is very frequent among patients affected with subclinical Becker's muscular dystrophy by MELACINI, P, FANIN, M, ANGELINI, C, DALLA VOLTA, S, DANIELI, G. A, VILLANOVA, C, MARTINELLO, F, MIORIN, M, FREDA, M. P, MIORELLI, M, MOSTACCIUOLO, M. L, FASOLI, G

“…Several cases of Becker's muscular dystrophy (BMD) have been reported, which showed mild or subclinical skeletal muscle involvement with an overt dilated…”
Get full text

Stimulatory effects of stress on gonadotropin secretion in estrogen-treated women by PUDER, J. J, FREDA, P. U, GOLAND, R. S, FERIN, M, WARDLAW, S. L

“…Although stress is known to inhibit the hypothalamic-pituitary-gonadal axis, recent studies in the monkey show that, under certain conditions, in the presence…”
Get full text

Genetic epidemiology of muscular dystrophies resulting from sarcoglycan gene mutations by Fanin, M, Duggan, D J, Mostacciuolo, M L, Martinello, F, Freda, M P, Sorarù, G, Trevisan, C P, Hoffman, E P, Angelini, C

“…BACKGROUND: The autosomal recessive limb-girdle muscular dystrophies (LGMDs) are a group of genetically heterogeneous muscle diseases characterised by…”
Get full text

Riboflavin therapy: Biochemical heterogeneity in two adult lipid storage myopathies by VERGANI, L, BARILE, M, ANGELINI, C, BURLINA, A. B, NIJTMANS, L, FREDA, M. P, BRIZIO, C, ZERBETTO, E, DABBENI-SALA, F

“…Two unrelated adult males, aged 36 (patient 1) and 25 (patient 2) years, presented with subacute carnitine-deficient lipid storage myopathy that was totally…”
Get full text

Estrogen modulates the hypothalamic-pituitary-adrenal and inflammatory cytokine responses to endotoxin in women by Puder, J J, Freda, P U, Goland, R S, Wardlaw, S L

“…Endotoxin stimulates the release of the inflammatory cytokines interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)-alpha, which are potent activators of…”
Get full text

Long-term treatment of prolactin-secreting macroadenomas with pergolide by FREDA, P. U, ANDREADIS, C. I, KHANDJI, A. G, KHOURY, M, BRUCE, J. N, JACOBS, T. P, WARDLAW, S. L

Get full text