Search Results - "Fred Naider"
-
1
A Paradigm for Peptide Hormone-GPCR Analyses
Published in Molecules (Basel, Switzerland) (18-09-2020)“…Work from our laboratories over the last 35 years that has focused on Ste2p, a G protein-coupled receptor (GPCR), and its tridecapeptide ligand α-factor is…”
Get full text
Journal Article -
2
Detection of intermolecular NOE interactions in large protein complexes
Published in Progress in nuclear magnetic resonance spectroscopy (01-11-2016)“…Intermolecular NOE interactions are invaluable for structure determination of biomolecular complexes by NMR and they represent the "gold-standard" amongst NMR…”
Get full text
Journal Article -
3
Dynamic roles for the N-terminus of the yeast G protein-coupled receptor Ste2p
Published in Biochimica et biophysica acta. Biomembranes (01-10-2017)“…The Saccharomyces cerevisiae α-factor receptor Ste2p has been used extensively as a model to understand the molecular mechanism of signal transduction by G…”
Get full text
Journal Article -
4
The methyl 13C-edited/13C-filtered transferred NOE for studying protein interactions with short linear motifs
Published in Journal of biomolecular NMR (01-12-2020)“…Many proteins interact with their ligand proteins by recognition of short linear motifs that are often intrinsically disordered. These interactions are usually…”
Get full text
Journal Article -
5
The N-terminus of the yeast G protein-coupled receptor Ste2p plays critical roles in surface expression, signaling, and negative regulation
Published in Biochimica et biophysica acta (01-04-2016)“…G protein-coupled receptors (GPCRs) are found in all eukaryotic cells examined to date where they function as membrane-bound proteins that bind a multitude of…”
Get full text
Journal Article -
6
Effects of chelator lipids, paramagnetic metal ions and trehalose on liposomes by solid-state NMR
Published in Solid state nuclear magnetic resonance (01-10-2018)“…The effects of various lipid bound paramagnetic metal ions on liposomes prepared in the presence of trehalose and chelator lipids are evaluated to observe…”
Get full text
Journal Article -
7
A solution NMR view of protein dynamics in the biological membrane
Published in Current opinion in structural biology (01-10-2011)“…► Critical cellular functions of membrane proteins are often related to their dynamics. ► NMR methods are well suited to study motions on a wide range of…”
Get full text
Journal Article -
8
An Oligopeptide Transporter Gene Family in Arabidopsis
Published in Plant physiology (Bethesda) (01-01-2002)“…We have identified nine oligopeptide transporter (OPT) orthologs (AtOPT1 to AtOPT9) in Arabidopsis. These proteins show significant sequence similarity to OPTs…”
Get full text
Journal Article -
9
Differential Regulation and Substrate Preferences in Two Peptide Transporters of Saccharomyces cerevisiae
Published in Eukaryotic Cell (01-10-2007)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
10
Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR
Published in Pharmacological research (01-01-2012)“…Signaling and internalization of Ste2p, a model G protein-coupled receptor (GPCR) from the yeast Saccharomyces cerevisiae, are reported to be regulated by…”
Get full text
Journal Article -
11
The First Extracellular Loop of the Saccharomyces cerevisiae G Protein-coupled Receptor Ste2p Undergoes a Conformational Change upon Ligand Binding
Published in The Journal of biological chemistry (06-04-2007)“…In this study of the Saccharomyces cerevisiae G protein-coupled receptor Ste2p, we present data indicating that the first extracellular loop (EL1) of the…”
Get full text
Journal Article -
12
Nutrient regulation of oligopeptide transport in Saccharomyces cerevisiae
Published in Microbiology (Society for General Microbiology) (01-10-2006)“…1 Department of Biochemistry, Cell and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA 2 Department of Microbiology, University of…”
Get full text
Journal Article -
13
Halo Assay for Toxic Peptides and Other Compounds in Microorganisms
Published in Bio-protocol (20-11-2016)“…We describe an assay for determination of toxicity in involving spotting of a toxic peptide on a lawn of yeast cells. This assay may be generalized to…”
Get full text
Journal Article -
14
Uptake Assay for Radiolabeled Peptides in Yeast
Published in Bio-protocol (20-11-2016)“…We describe an assay for measuring the uptake of radioactive peptides into the yeast . The methods presented here can be adapted to measure a variety of…”
Get full text
Journal Article -
15
Interacting Residues in an Activated State of a G Protein-coupled Receptor
Published in The Journal of biological chemistry (27-01-2006)“…Ste2p, the G protein-coupled receptor (GPCR) for the tridecapeptide pheromone α-factor of Saccharomyces cerevisiae, was used as a model GPCR to investigate the…”
Get full text
Journal Article -
16
Peptides in the treatment of AIDS
Published in Current opinion in structural biology (01-08-2009)“…Fusion of HIV-1 and target cells is mediated by the envelope protein gp41 that undergoes a series of conformational changes during the process of infection…”
Get full text
Journal Article -
17
The PTR family: a new group of peptide transporters
Published in Molecular microbiology (01-06-1995)“…The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a…”
Get more information
Journal Article -
18
Transmembrane domain prediction and consensus sequence identification of the oligopeptide transport family
Published in Research in microbiology (01-05-2006)“…Few polytopic membrane proteins have had their topology determined experimentally. Often, researchers turn to an algorithm to predict where the transmembrane…”
Get full text
Journal Article -
19
Affinity purification and characterization of a G-protein coupled receptor, Saccharomyces cerevisiae Ste2p
Published in Protein expression and purification (01-11-2007)“…We present an example of expression and purification of a biologically active G-protein coupled receptor (GPCR) from yeast. An expression vector was…”
Get full text
Journal Article -
20
Enkephalins Are Transported by a Novel Eukaryotic Peptide Uptake System
Published in The Journal of biological chemistry (04-02-2000)“…We have identified an oligopeptide transporter in the yeast Saccharomyces cerevisiae which mediates the uptake of tetra- and pentapeptides, including the…”
Get full text
Journal Article