Search Results - "Frebel, Helge"

Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice by Frebel, Helge, Nindl, Veronika, Schuepbach, Reto A, Braunschweiler, Thomas, Richter, Kirsten, Vogel, Johannes, Wagner, Carsten A, Loffing-Cueni, Dominique, Kurrer, Michael, Ludewig, Burkhard, Oxenius, Annette

“…The inhibitory programmed death 1 (PD-1)-programmed death ligand 1 (PD-L1) pathway contributes to the functional down-regulation of T cell responses during…”
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IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection by Schmitz, Iwana, Schneider, Christoph, Fröhlich, Anja, Frebel, Helge, Christ, Daniel, Leonard, Warren J, Sparwasser, Tim, Oxenius, Annette, Freigang, Stefan, Kopf, Manfred

“…Foxp3+ regulatory T (Treg) cells are essential for the maintenance of immune homeostasis and tolerance. During viral infections, Treg cells can limit the…”
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Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies by Trundley, Anita, Frebel, Helge, Jones, Des, Chang, Chiwen, Trowsdale, John

“…KIR3DL1 is one of the best‐characterised inhibitory NK cell receptors. Unusually, one common allele at the 3DL1 locus encodes an activating receptor known as…”
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The risks of targeting co-inhibitory pathways to modulate pathogen-directed T cell responses by Frebel, Helge, Oxenius, Annette

“…The identification of T cell co-inhibition as a central mechanism in the regulation of adaptive immunity during infectious diseases provides new opportunities…”
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How chronic viral infections impact on antigen-specific T-cell responses by Frebel, Helge, Richter, Kirsten, Oxenius, Annette

“…Persistent viral infections are, by definition, associated with ineffective antiviral immunity, in particular those infections caused by viruses that are…”
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IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection: e1003362 by Schmitz, Iwana, Schneider, Christoph, Fröhlich, Anja, Frebel, Helge, Christ, Daniel, Leonard, Warren J, Sparwasser, Tim, Oxenius, Annette, Freigang, Stefan, Kopf, Manfred

“…Foxp3+ regulatory T (Treg) cells are essential for the maintenance of immune homeostasis and tolerance. During viral infections, Treg cells can limit the…”
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