Search Results - "Frazier, L M"

Evolutionary evidence of the effect of rare variants on disease etiology by Gorlov, IP, Gorlova, OY, Frazier, ML, Spitz, MR, Amos, CI

“…Gorlov IP, Gorlova OY, Frazier ML, Spitz MR, Amos CI. Evolutionary evidence of the effect of rare variants on disease etiology. The common disease/common…”
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Phase II trial of imatinib mesylate in patients with metastatic melanoma by Kim, K B, Eton, O, Davis, D W, Frazier, M L, McConkey, D J, Diwan, A H, Papadopoulos, N E, Bedikian, A Y, Camacho, L H, Ross, M I, Cormier, J N, Gershenwald, J E, Lee, J E, Mansfield, P F, Billings, L A, Ng, C S, Charnsangavej, C, Bar-Eli, M, Johnson, M M, Murgo, A J, Prieto, V G

“…Metastatic melanoma cells express a number of protein tyrosine kinases (PTKs) that are considered to be targets for imatinib. We conducted a phase II trial of…”
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Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines : Growth inhibition by nonsteroidal anti-inflammatory drugs by MOLINA, M. A, SITJA-ARNAU, M, LEMOINE, M. G, FRAZIER, M. L, SINICROPE, F. A

“…Cyclooxygenase (COX)-2 mRNA and protein expression were found to be frequently elevated in human pancreatic adenocarcinomas and cell lines derived from such…”
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Genotype–phenotype correlations in Peutz-Jeghers syndrome by Amos, C I, Keitheri-Cheteri, M B, Sabripour, M, Wei, C, McGarrity, T J, Seldin, M F, Nations, L, Lynch, P M, Fidder, H H, Friedman, E, Frazier, M L

“…Background and aims: Peutz-Jeghers syndrome (PJS) is a dominantly inherited disorder often caused by mutations in STK11. Time to onset of symptoms was…”
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Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers by Sinicrope, Frank A., Lemoine, Michael, Xi, Lixuan, Lynch, Patrick M., Cleary, Karen R., Shen, Yu, Frazier, Marsha L.

“…Background & Aims: Cyclooxygenase (COX) enzymes catalyze the conversion of arachidonic acid to prostaglandins. Evidence suggests that nonsteroidal…”
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Changes in screening behaviors and attitudes toward screening from pre-test genetic counseling to post-disclosure in Lynch syndrome families by Burton-Chase, AM, Hovick, SR, Peterson, SK, Marani, SK, Vernon, SW, Amos, CI, Frazier, ML, Lynch, PM, Gritz, ER

“…The purpose of this study was to examine colonoscopy adherence and attitudes toward colorectal cancer (CRC) screening in individuals who underwent Lynch…”
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Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer by SHOUMING KONG, AMOS, C. I, LUTHRA, R, LYNCH, P. M, LEVIN, B, FRAZIER, M. L

“…A common polymorphism in the cyclin D1 gene enhances the gene's alternate splicing. The alternatively spliced product encodes an altered protein that does not…”
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The unit of analysis error in studies about physicians' patient care behavior by DIVINE, G. W, BROWN, J. T, FRAZIER, L. M

“…To estimate the frequency with which patients are incorrectly used as the unit of analysis among statistical calculations in published studies of physicians'…”
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Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p by AMOS, C. I, BALI, D, SELDIN, M. F, THIEL, T. J, ANDERSON, J. P, GOURLEY, I, FRAZIER, M. L, LYNCH, P. M, LUCHTEFELD, M. A, YOUNG, A, MCGARRITY, T. J

“…Peutz-Jeghers syndrome (PJS) was recently mapped in a single report to the telomeric region of chromosome 19p (A. Hemminki et al., Nat. Genet., 15: 87-90,…”
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Cyclin D1 Polymorphism and Increased Risk of Colorectal Cancer at Young Age by Kong, Shouming, Wei, Qingyi, Amos, Christopher I., Lynch, Patrick M., Levin, Bernard, Zong, Jihong, Frazier, Marsha L.

“…genes and cyclin D1, allowing the deleterious allele of cyclin D1 to influence…”
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DNA Pooling in Mutation Detection with Reference to Sequence Analysis by Amos, Christopher I., Frazier, Marsha L., Wang, Wenfu

“…We discuss pooling methods of mutation detection for identifying rare mutations. We provide mathematical formulae for obtaining the optimal pool size as a…”
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Evidence for linkage of postchallenge insulin levels with intestinal fatty acid-binding protein (FABP2) in Mexican-Americans by Mitchell, B. D., Kammerer, C. M., O'Connell, P., Harrison, C. R., Manire, M., Shipman, P., Moyer, M. P., Stern, M. P., Frazier, M. L.

“…Evidence for linkage of postchallenge insulin levels with intestinal fatty acid-binding protein (FABP2) in Mexican-Americans. B D Mitchell , C M Kammerer , P…”
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Loci for efficient detection of microsatellite instability in hereditary non-polyposis colorectal cancer by Frazier, M L, Sinicrope, F A, Amos, C I, Cleary, K R, Lynch, P M, Levin, B, Luthra, R

“…Most hereditary non-polyposis colorectal cancer (HNPCC) is due to germline mutations in DNA mismatch repair genes. Tumors arising as a result of these…”
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Can physician education lower the cost of prescription drugs? A prospective, controlled trial by Frazier, L M, Brown, J T, Divine, G W, Fleming, G R, Philips, N M, Siegal, W C, Khayrallah, M A

“…To determine whether an educational program featuring a drug cost manual can assist physicians in reducing their patients' out-of-pocket prescription drug…”
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Current applications of genetic technology in predisposition testing and microsatellite instability assays by FRAZIER, Marsha L, SU, Li-Kuo, AMOS, Christopher I, LYNCH, Patrick M

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Characterization of aquatic bacteria and cloning of genes specifying partial degradation of 2,4-dichlorophenoxyacetic acid by AMY, P. S, SCHULKE, J. W, FRAZIER, L. M, SEIDLER, R. J

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cis-acting elements required for expression of the nonspecific cross- reacting antigen gene in colorectal carcinoma by Jones, DV, Wu, E, Manire, M, Frazier, ML

“…BACKGROUND & AIMS: The nonspecific cross-reacting antigen (NCA) is a cell adhesion molecule, and the messenger RNA for NCA is overexpressed in 92% of…”
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Workplace reproductive problems by Frazier, L M

“…Occupational exposures can harm reproductive processes in men or women. Exposures may affect fertility, pregnancy outcomes or the child's health after…”
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Evidence for a major gene for type II diabetes and linkage analyses with selected candidate genes in Mexican-Americans by Stern, M. P., Mitchell, B. D., Blangero, J., Reinhart, L., Krammerer, C. M., Harrison, C. R., Shipman, P. A., O'Connell, P., Frazier, M. L., MacCluer, J. W.

“…Evidence for a major gene for type II diabetes and linkage analyses with selected candidate genes in Mexican-Americans. M P Stern , B D Mitchell , J Blangero ,…”
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Loss of p21WAF1/Cip1 protein expression accompanies progression of sporadic colorectal neoplasms but not hereditary nonpolyposis colorectal cancers by Sinicrope, F A, Roddey, G, Lemoine, M, Ruan, S, Stephens, L C, Frazier, M L, Shen, Y, Zhang, W

“…p21 (p21WAF1/Cip1), a cyclin-dependent kinase inhibitor, induces G1 arrest and can inhibit the activity of the proliferating cell nuclear antigen (PCNA). We…”
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