Search Results - "Frazao, Nelson"

Shared Evolutionary Path in Social Microbiomes by Frazão, Nelson, Gordo, Isabel

“…Abstract Social networks can influence the ecology of gut bacteria, shaping the species composition of the gut microbiome in humans and other animals. Gut…”
Get full text

Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut by Frazão, Nelson, Sousa, Ana, Lässig, Michael, Gordo, Isabel

“…Bacteria evolve by mutation accumulation in laboratory experiments, but tempo and mode of evolution in natural environments are largely unknown. Here, we study…”
Get full text

DNA Breaks-Mediated Fitness Cost Reveals RNase HI as a New Target for Selectively Eliminating Antibiotic-Resistant Bacteria by Balbontín, Roberto, Frazão, Nelson, Gordo, Isabel

“…Abstract Antibiotic resistance often generates defects in bacterial growth called fitness cost. Understanding the causes of this cost is of paramount…”
Get full text

Evolution of commensal bacteria in the intestinal tract of mice by Sousa, Ana, Frazão, Nelson, Ramiro, Ricardo S, Gordo, Isabel

“…Graphical abstract…”
Get full text

Ecotype formation and prophage domestication during gut bacterial evolution by Frazão, Nelson, Gordo, Isabel

“…How much bacterial evolution occurs in our intestines and which factors control it are currently burning questions. The formation of new ecotypes, some of…”
Get full text

Impact of a single dose of the 7-valent pneumococcal conjugate vaccine on colonization by Frazão, Nelson, Sá-Leão, Raquel, de Lencastre, Hermínia

“…Abstract The impact of the 7-valent pneumococcal conjugate vaccine (PCV7) on the pneumococcal flora has been mostly studied without evaluating multiple…”
Get full text

Ability of Antibiotic-Resistant Nonvaccine-Type Pneumococcal Clones to Cause Otitis Media in an Infant Mouse Model of Pneumococcal-Influenza Virus Coinfection by Frazão, Nelson, Hermans, Peter, van Selm, Saskia, Sá-Leão, Raquel, de Lencastre, Hermínia, Tomasz, Alexander, Diavatopoulos, Dimitri

“…The introduction of the 7-valent pneumococcal conjugate vaccine in Portugal resulted in reduced carriage in children by vaccine-type strains and an increased…”
Get more information

In vivo capsular switch in Streptococcus pneumoniae--analysis by whole genome sequencing by Hu, Fen Z, Eutsey, Rory, Ahmed, Azad, Frazao, Nelson, Powell, Evan, Hiller, N Luisa, Hillman, Todd, Buchinsky, Farrel J, Boissy, Robert, Janto, Benjamin, Kress-Bennett, Jennifer, Longwell, Mark, Ezzo, Suzanne, Post, J Christopher, Nesin, Mirjana, Tomasz, Alexander, Ehrlich, Garth D

“…Two multidrug resistant strains of Streptococcus pneumoniae - SV35-T23 (capsular type 23F) and SV36-T3 (capsular type 3) were recovered from the nasopharynx of…”
Get full text

Identification, prevalence and population structure of non-typable Streptococcus pneumoniae in carriage samples isolated from preschoolers attending day-care centres by Sa-Leao, Raquel, Simoes, Alexandra S, Nunes, Sonia, Sousa, Natacha G, Frazao, Nelson, de Lencastre, Herminia

“…1 Molecular Genetics Laboratory, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Rua da Quinta Grande, 6, 2780-106 Oeiras, Portugal…”
Get full text

Analysis of Invasiveness of Pneumococcal Serotypes and Clones Circulating in Portugal before Widespread Use of Conjugate Vaccines Reveals Heterogeneous Behavior of Clones Expressing the Same Serotype by SA-LEAO, Raquel, PINTO, Francisco, AGUIAR, Sandra, NUNES, Sonia, CARRICO, Joao A, FRAZAO, Nelson, GONCALVES-SOUSA, Natacha, MELO-CRISTINO, José, DE LENCASTRE, Hermínia, RAMIREZ, Mário

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Mutation accumulation and horizontal gene transfer in Escherichia coli colonizing the gut of old mice by Barreto, Hugo C., Frazão, Nelson, Sousa, Ana, Konrad, Anke, Gordo, Isabel

“…The ecology and environment of the microbes that inhabit the mammalian intestine undergoes several changes as the host ages. Here, we ask if the selection…”
Get full text

Virulence potential and genome-wide characterization of drug resistant Streptococcus pneumoniae clones selected in vivo by the 7-valent pneumococcal conjugate vaccine by Frazão, Nelson, Hiller, N Luisa, Powell, Evan, Earl, Josh, Ahmed, Azad, Sá-Leão, Raquel, de Lencastre, Hermínia, Ehrlich, Garth D, Tomasz, Alexander

“…We used mouse models of pneumococcal colonization and disease combined with full genome sequencing to characterize three major drug resistant clones of S…”
Get full text

Effect of the Seven-Valent Conjugate Pneumococcal Vaccine on Carriage and Drug Resistance of Streptococcus pneumoniae in Healthy Children Attending Day-Care Centers in Lisbon by Frazão, Nelson, Brito-Avô, António, Simas, Carla, Saldanha, Joana, Mato, Rosario, Nunes, Sónia, Sousa, Natacha G, Carriço, João A, Almeida, Jonas S, Santos-Sanches, Ilda, de Lencastre, Hermínia

“…AIMS:Prospective study to evaluate the impact of the 7-valent pneumococcal conjugate vaccine (Prevenar) on the nasopharyngeal (NP) carriage of drug-resistant…”
Get full text

Properties of Novel International Drug-Resistant Pneumococcal Clones Identified in Day-Care Centers of Lisbon, Portugal by Sousa, Natacha G, Sá-Leão, Raquel, Crisóstomo, M. Inês, Simas, Carla, Nunes, Sónia, Frazão, Nelson, Carriço, João A, Mato, Rosario, Santos-Sanches, Ilda, de Lencastre, Hermínia

“…In this study, 61 drug-resistant Streptococcus pneumoniae strains were characterized by multilocus sequence typing (MLST). These strains were representatives…”
Get full text

Virulence Potential and Genome-Wide Characterization of Drug Resistant Streptococcus pneumoniae Clones Selected In Vivo by the 7-Valent Pneumococcal Conjugate Vaccine: e74867 by Frazao, Nelson, Hiller, N Luisa, Powell, Evan, Earl, Josh, Ahmed, Azad, Sa-Leao, Raquel, Lencastre, Herminia de, Ehrlich, Garth D, Tomasz, Alexander

“…We used mouse models of pneumococcal colonization and disease combined with full genome sequencing to characterize three major drug resistant clones of S…”
Get full text

Identification, prevalence and population structure of non-typable Streptococcus pneumoniae in carriage samples isolated from preschoolers attending day-care centres : Molecular biology of the pneumococcus by SA-LEAO, Raquel, SIMOES, Alexandra S, NUNES, Sonia, SOUSA, Natacha G, FRAZAO, Nelson, DE LENCASTRE, Herminia

Get full text

Shift in the Pneumococcal Nasopharyngeal Flora After the 7-Valent Conjugate Vaccine: Epidemiological Studies and Testing Pathogenic Potential in Animal Models by Frazão, Nelson

“…Although it exists mostly as a commensal bacterium colonizing the human nasopharynx, particularly in children, the Gram-positive bacterium Streptococcus…”
Get full text