Search Results - "Frawley, Rachel"
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Immunotoxicity of N-butylbenzenesulfonamide: impacts on immune function in adult mice and developmentally exposed rats
Published in Toxicological sciences (30-10-2023)“…Abstract N-butylbenzenesulfonamide (NBBS) is a high-production volume plasticizer that is an emerging contaminant of concern for environmental and human…”
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Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague-Dawley rats and B6C3F1/N mice when administered by oral gavage for 28 days
Published in Journal of immunotoxicology (01-01-2018)“…Poly- and perfluoroalkyl substances (PFAS) are chemically and thermally stable, hydrophobic, lipophobic compounds used in stain repellants and water and oil…”
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Evaluation of skin sensitization induced by four ionic liquids
Published in Journal of applied toxicology (01-03-2022)“…Ionic liquids (ILs) are synthetic solvents used as replacements for volatile organic solvents. Human exposure occurs through dermal or oral routes. In rodents,…”
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Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies
Published in Toxicology (Amsterdam) (01-08-2020)“…2-Methoxy-4-nitroaniline (MNA), an intermediate in the synthesis of azo dyes used in textiles and paints, is structurally similar to carcinogenic anilines…”
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Markers of inflammation
Published in Methods in molecular biology (Clifton, N.J.) (2010)“…Inflammation is a complex and necessary component of an organism's response to biological, chemical or physical stimuli. In the acute phase, cells of the…”
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Relative potency for altered humoral immunity induced by polybrominated and polychlorinated dioxins/furans in female B6C3F1/N mice
Published in Toxicological sciences (01-06-2014)“…The use of brominated flame retardants and incineration of bromine-containing materials has lead to an increase in polybrominated dibenzo-p-dioxins and…”
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Immunomodulatory effects of black cohosh (Actaea racemosa) extract in female B6C3F1/N mice
Published in Toxicology (Amsterdam) (07-06-2013)“…Black cohosh extracts (BCE; Actaea racemosa) are being used worldwide as an alternative to hormone replacement therapy for the management of menstrual and…”
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Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague-Dawley rats and B 6 C 3 F 1 /N mice when administered by oral gavage for 28 days
Published in Journal of immunotoxicology (01-12-2018)“…Poly- and perfluoroalkyl substances (PFAS) are chemically and thermally stable, hydrophobic, lipophobic compounds used in stain repellants and water and oil…”
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Immunotoxic effects of sodium tungstate dihydrate on female B6C3F1/N mice when administered in drinking water
Published in Journal of immunotoxicology (01-09-2016)“…Tungsten is a naturally occurring, high-tensile strength element that has been used in a number of consumer products. Tungsten has been detected in soil,…”
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Unlocking the Potential of Clustering and Classification Approaches: Navigating Supervised and Unsupervised Chemical Similarity
Published in Environmental health perspectives (01-08-2024)“…The field of toxicology has witnessed substantial advancements in recent years, particularly with the adoption of new approach methodologies (NAMs) to…”
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Evaluation of immunotoxicity of sodium metavanadate following drinking water exposure in female B6C3F1/N mice in a 28-day study
Published in Journal of applied toxicology (01-11-2023)“…Sodium metavanadate (NaVO ) is a pentavalent vanadium compound used in the metal industry and dietary supplements; human exposure occurs through inhalation of…”
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Gene Expression Alterations in Immune System Pathways in the Thymus after Exposure to Immunosuppressive Chemicals
Published in Environmental health perspectives (01-03-2011)“…Background: Deregulation of positive and negative selection, antigen presentation, or apoptosis in the thymus can lead to immunosuppression or autoimmunity…”
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Immunomodulatory effects of black cohosh ( Actaea racemosa ) extract in female B6 C3 F1 /N mice
Published in Toxicology (Amsterdam) (2013)“…Abstract Black cohosh extracts (BCE; Actaea racemosa ) are being used worldwide as an alternative to hormone replacement therapy for the management of…”
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