Search Results - "Fratte, Chiara Dalle"
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Point‐of‐Care Testing for the Detection of MicroRNAs: Towards Liquid Biopsy on a Chip
Published in Angewandte Chemie International Edition (18-12-2023)“…Point‐of‐care (PoC) testing is revolutionizing the healthcare sector improving patient care in daily hospital practice and allowing reaching even remote…”
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Circulating-Free DNA Analysis in Hepatocellular Carcinoma: A Promising Strategy to Improve Patients' Management and Therapy Outcomes
Published in International journal of molecular sciences (05-11-2019)“…Hepatocellular carcinoma (HCC) is the sixth most common malignancy worldwide, representing the third leading cause of cancer-related deaths. HCC genetic…”
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3
Binary classification of copy number alteration profiles in liquid biopsy with potential clinical impact in advanced NSCLC
Published in Scientific reports (09-08-2024)“…Liquid biopsy has recently emerged as an important tool in clinical practice particularly for lung cancer patients. We retrospectively evaluated cell-free DNA…”
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4
Impact of ABCG2 and ABCB1 Polymorphisms on Imatinib Plasmatic Exposure: An Original Work and Meta-Analysis
Published in International journal of molecular sciences (07-02-2023)“…Adequate imatinib plasma levels are necessary to guarantee an efficacious and safe treatment in gastrointestinal stromal tumor (GIST) and chronic myeloid…”
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5
Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA
Published in EBioMedicine (01-12-2020)“…Targeted therapies (TKI) have improved the prognosis of ALK-rearranged lung cancer (ALK+ NSCLC), but clinical courses vary widely. Early identification and…”
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The use of therapeutic drug monitoring to highlight an over-looked drug-drug interaction leading to imatinib treatment failure
Published in Daru (15-06-2023)“…Background Chronic oral anticancer therapies, are increasingly prescribed and present new challenges including the enhanced risk of overlooked drug-drug…”
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Clonal Selection of a Novel Deleterious TP53 Somatic Mutation Discovered in ctDNA of a KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumor Resistant to Imatinib
Published in Frontiers in pharmacology (07-02-2020)“…The standard of care for the first-line treatment of advanced gastrointestinal stromal tumor (GIST) is represented by imatinib, which is given daily at a…”
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The relevance of citizen involvement in Health Technology Assessment. A concrete application in the assessment of HPV co-testing in the Autonomous Province of Trento
Published in Epidemiology, biostatistics, and public health (06-05-2022)“…Background Specific programs have been developed in the latest decades to involve patients in Health Technology Assessments (HTAs). However, there are no…”
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Estimating the Effectiveness of DPYD Genotyping in Italian Individuals Suffering from Cancer Based on the Cost of Chemotherapy-Induced Toxicity
Published in American journal of human genetics (06-06-2019)“…Fluoropyrimidines (FLs) have been widely used for more than 60 years against a range of solid tumors and still remains the cornerstone for the treatment of…”
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Therapeutic drug monitoring and pharmacogenetics to tune imatinib exposure in gastrointestinal stromal tumor patients: hurdles and perspectives for clinical implementation
Published in Pharmacogenomics (01-12-2023)“…Tweetable abstract Present evidence supports the use of intensified pharmacologic monitoring of #imatinib including #TherapeuticDrugMonitoring and #PGx to…”
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CYP2D6 and CYP2C8 pharmacogenetics and pharmacological interactions to predict imatinib plasmatic exposure in GIST patients
Published in British journal of clinical pharmacology (01-03-2023)“…Aims Patients on treatment with oral fixed dose imatinib are frequently under‐ or overexposed to the drug. We investigated the association between the gene…”
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The Genotype for DPYD Risk Variants in Patients With Colorectal Cancer and the Related Toxicity Management Costs in Clinical Practice
Published in Clinical pharmacology and therapeutics (01-04-2019)“…Lack of information on the clinical utility of preemptive DPYD screening before fluoropyrimidine treatment is a major barrier preventing its use in clinical…”
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13
Point‐of‐Care Testing for the Detection of MicroRNAs: Towards Liquid Biopsy on a Chip
Published in Angewandte Chemie (18-12-2023)“…Point‐of‐care (PoC) testing is revolutionizing the healthcare sector improving patient care in daily hospital practice and allowing reaching even remote…”
Get full text
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14
A Panel of Tumor Biomarkers to Predict Complete Pathological Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer
Published in Oncology research (31-01-2022)“…Pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients is related to a favorable prognosis. The…”
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Association of Sodium-Glucose Cotransporter 2 Inhibitors with Osteomyelitis and Other Lower Limb Safety Outcomes in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Published in Journal of clinical medicine (09-06-2023)“…Our aim was to evaluate osteomyelitis and other major lower limb safety outcomes (i.e., peripheral artery disease or PAD, ulcers, atraumatic fractures,…”
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SMAD3 Host and Tumor Profiling to Identify Locally Advanced Rectal Cancer Patients at High Risk of Poor Response to Neoadjuvant Chemoradiotherapy
Published in Frontiers in pharmacology (24-12-2021)“…Identifying patients at risk of poor response to neoadjuvant chemoradiotherapy (nCRT) is an emerging clinical need in locally advanced rectal cancer (LARC)…”
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The use of pharmacogenetics to increase the safety of colorectal cancer patients treated with fluoropyrimidines
Published in Cancer drug resistance (01-01-2019)“…Fluoropyrimidines (FP) are given in the combination treatment of the advanced disease or as monotherapy in the neo-adjuvant and adjuvant treatment of…”
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Economic analysis of remote monitoring in patients with implantable cardioverter defibrillators or cardiac resynchronization therapy defibrillators in the Trento area, Italy
Published in Frontiers in cardiovascular medicine (25-05-2023)“…Remote monitoring (RM) technologies have the potential to improve patient care by increasing compliance, providing early indications of heart failure (HF), and…”
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Robot-assisted laparoscopic prostatectomy: a costs and break-even point analysis for decision-making in a university hospital and a regional healthcare system in Northern Italy
Published in Epidemiology, biostatistics, and public health (13-05-2022)“…BACKGROUND: Robotic Assisted Radical Prostatectomy (RALP) is one of the most expensive urological innovations. Prices of the “Da Vinci System” range from…”
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Impact of IABCG2/I and IABCB1/I Polymorphisms on Imatinib Plasmatic Exposure: An Original Work and Meta-Analysis
Published in International journal of molecular sciences (01-02-2023)“…Adequate imatinib plasma levels are necessary to guarantee an efficacious and safe treatment in gastrointestinal stromal tumor (GIST) and chronic myeloid…”
Get full text
Journal Article