Search Results - "Fraterman, Sven"

Trends in the use of liquid biopsy in oncology by Xie, Wen, Suryaprakash, Smruthi, Wu, Chun, Rodriguez, Andrew, Fraterman, Sven

Get full text

Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes by Nekrasov, Maxim, Klymenko, Tetyana, Fraterman, Sven, Papp, Bernadett, Oktaba, Katarzyna, Köcher, Thomas, Cohen, Adrian, Stunnenberg, Hendrik G, Wilm, Matthias, Müller, Jürg

“…PRC2 is thought to be the histone methyltransferase (HMTase) responsible for H3‐K27 trimethylation at Polycomb target genes. Here we report the biochemical…”
Get full text

The Sec14 Homology Module of Neurofibromin Binds Cellular Glycerophospholipids: Mass Spectrometry and Structure of a Lipid Complex by Welti, Stefan, Fraterman, Sven, D’Angelo, Igor, Wilm, Matthias, Scheffzek, Klaus

“…Neurofibromin is the protein product of the tumor suppressor gene NF1, alterations of which are responsible for the pathogenesis of the common disorder…”
Get full text

Quantitative Proteomics Profiling of Sarcomere Associated Proteins in Limb and Extraocular Muscle Allotypes by Fraterman, Sven, Zeiger, Ulrike, Khurana, Tejvir S., Wilm, Matthias, Rubinstein, Neal A.

“…The sarcomere is the major structural and functional unit of striated muscle. Approximately 65 different proteins have been associated with the sarcomere, and…”
Get full text

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB by Müller, Jürg, Muir, Tom W, Wilm, Matthias, McGinty, Robert K, Oktaba, Katarzyna, de Ayala Alonso, Andrés Gaytán, Ly-Hartig, Nga, Fraterman, Sven, Scheuermann, Johanna C

“…Polycomb group (PcG) proteins are transcriptional repressors that control processes ranging from the maintenance of cell fate decisions and stem cell…”
Get full text

The Nonspecific Lethal Complex Is a Transcriptional Regulator in Drosophila by Raja, Sunil Jayaramaiah, Charapitsa, Iryna, Conrad, Thomas, Vaquerizas, Juan M., Gebhardt, Philipp, Holz, Herbert, Kadlec, Jan, Fraterman, Sven, Luscombe, Nicholas M., Akhtar, Asifa

“…Here, we report the biochemical characterization of the nonspecific lethal (NSL) complex (NSL1, NSL2, NSL3, MCRS2, MBD-R2, and WDS) that associates with the…”
Get full text

Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements by Alfieri, Claudio, Gambetta, Maria Cristina, Matos, Raquel, Glatt, Sebastian, Sehr, Peter, Fraterman, Sven, Wilm, Matthias, Müller, Jürg, Müller, Christoph W

“…Polycomb group (PcG) protein complexes repress developmental regulator genes by modifying their chromatin. How different PcG proteins assemble into complexes…”
Get full text

Combination of peptide OFFGEL fractionation and label-free quantitation facilitated proteomics profiling of extraocular muscle by Fraterman, Sven, Zeiger, Ulrike, Khurana, Tejvir S., Rubinstein, Neal A., Wilm, Matthias

“…Several label‐free quantitation strategies have been introduced that obliterate the need for expensive isotopically labeled molecules. However label‐free…”
Get full text

Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail by Thoma, Christian, Fraterman, Sven, Gentzel, Marc, Wilm, Matthias, Hentze, Matthias W

“…Eukaryotic mRNAs possess a poly(A) tail that enhances translation via the (7)mGpppN cap structure or internal ribosome entry sequences (IRESs). Here we address…”
Get full text

Identification of Acetylcholine Receptor Subunits Differentially Expressed in Singly and Multiply Innervated Fibers of Extraocular Muscles by Fraterman, Sven, Khurana, Tejvir S, Rubinstein, Neal A

“…To identify the acetylcholine receptor (AChR) isoforms among the neuromuscular junctions (NMJs) of singly and multiply innervated fibers (SIFs and MIFs) of rat…”
Get full text

The human T locus and spina bifida risk by JENSEN, Liselotte E, BARBAUX, Sandrine, HOESS, Katy, FRATERMAN, Sven, WHITEHEAD, Alexander S, MITCHELL, Laura E

“…The transcription factor T is essential for mesoderm formation and axial development during embryogenesis. Embryonic genotype for a single-nucleotide…”
Get full text