Search Results - "Fraser‐Browne, Carol"
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Contour variation is a primary source of error when delivering post prostatectomy radiotherapy: Results of the Trans‐Tasman Radiation Oncology Group 08.03 Radiotherapy Adjuvant Versus Early Salvage (RAVES) benchmarking exercise
Published in Journal of medical imaging and radiation oncology (01-06-2019)“…Introduction Variation in target volume delineation from clinical trial protocols has been shown to contribute to poorer patient outcomes. A clinical trial…”
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Phase 3 Trial of Domiciliary Humidification to Mitigate Acute Mucosal Toxicity During Radiation Therapy for Head-and-Neck Cancer: First Report of Trans Tasman Radiation Oncology Group (TROG) 07.03 RadioHUM Study
Published in International journal of radiation oncology, biology, physics (01-03-2014)“…Purpose To assess the impact of domicile-based humidification on symptom burden during radiation therapy (RT) for head-and-neck (H&N) cancer. Methods and…”
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A Phase III trial to investigate the timing of radiotherapy for prostate cancer with high‐risk features: background and rationale of the Radiotherapy – Adjuvant Versus Early Salvage (RAVES) trial
Published in BJU international (01-03-2014)“…Objectives To test the hypothesis that observation with early salvage radiotherapy (SRT) is not inferior to ‘standard’ treatment with adjuvant RT (ART) with…”
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Optimizing Radiation Therapy Quality Assurance in Clinical Trials: A TROG 08.03 RAVES Substudy
Published in International journal of radiation oncology, biology, physics (01-12-2015)“…Purpose To explore site- and clinician-level factors associated with protocol violations requiring real-time-review (RTR) resubmission in a multicenter…”
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Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data
Published in The Lancet (British edition) (31-10-2020)“…It is unclear whether adjuvant or early salvage radiotherapy following radical prostatectomy is more appropriate for men who present with localised or locally…”
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Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial
Published in The lancet oncology (01-10-2020)“…Adjuvant radiotherapy has been shown to halve the risk of biochemical progression for patients with high-risk disease after radical prostatectomy. Early…”
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Lentiviral Gene Therapy for Artemis-Deficient SCID
Published in The New England journal of medicine (22-12-2022)“…Severe combined immunodeficiency caused by mutations in the gene encoding a DNA-repair enzyme called Artemis is difficult to treat. This study involving 10…”
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Azacitidine Administration Following Hematopoietic Stem Cell Transplantation Is Safe and Feasible in Children with Acute Leukemia
Published in Blood (02-12-2016)“…Introduction High dose chemotherapy with or without radiation followed by hematopoietic stem cell transplantation (HSCT) is standard therapy for pediatric…”
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Dovitinib in first-line metastatic renal cell carcinoma and correlation of efficacy with tumor gene status: A phase II clinical trial
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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Dovitinib in first-line renal cell carcinoma: An investigation into tumour gene status and correlation with efficacy: A phase II clinical trial
Published in Journal of clinical oncology (01-02-2014)“…Abstract only 443 Background: Dovitinib is an anti-VEGFR tyrosine kinase inhibitor, differentiated by its inhibition of FGFR-1,-2,-3 and PDGFRβ. We evaluated…”
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A P hase III trial to investigate the timing of radiotherapy for prostate cancer with high‐risk features: background and rationale of the Radiotherapy – Adjuvant Versus Early Salvage ( RAVES ) trial
Published in BJU international (01-03-2014)“…Objectives To test the hypothesis that observation with early salvage radiotherapy ( SRT ) is not inferior to ‘standard’ treatment with adjuvant RT ( ART )…”
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What is optimal timing of post prostatectomy radiotherapy? Is adjuvant radiotherapy equivalent to early salvage radiotherapy? The “RAVES” phase III randomized clinical trial
Published in Journal of clinical oncology (20-05-2012)“…Abstract only TPS4690 Background: Three randomised trials have demonstrated a significant benefit of adjuvant post prostatectomy radiotherapy in patients with…”
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Early Outcome of a Phase I/II Clinical Trial (NCT03538899) of Gene-Corrected Autologous CD34+ Hematopoietic Cells and Low-Exposure Busulfan in Newly Diagnosed Patients with Artemis-Deficient Severe Combined Immunodeficiency (ART-SCID)
Published in Biology of blood and marrow transplantation (01-03-2020)“…ART-SCID represents ∼3% of all SCID, but occurs in 1/2000 births in Athabascan-speaking Native Americans. Artemis protein, encoded by DCLRE1C, is essential for…”
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