Search Results - "Fraser, Rupsha"
-
1
Killer Timing: The Temporal Uterine Natural Killer Cell Differentiation Pathway and Implications for Female Reproductive Health
Published in Frontiers in endocrinology (Lausanne) (27-06-2022)“…Natural killer (NK) cells are the predominant maternal uterine immune cell component, and they densely populate uterine mucosa to promote key changes in the…”
Get full text
Journal Article -
2
Remodelling at the maternal–fetal interface: relevance to human pregnancy disorders
Published in Reproduction (Cambridge, England) (01-12-2010)“…In human pregnancy, successful placentation and remodelling of the uterine vasculature require the integration of a number of stages, which are crucial for a…”
Get full text
Journal Article -
3
Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines
Published in Trends in molecular medicine (01-04-2023)“…Existing SARS-CoV-2 vaccination programmes have several drawbacks: (i) low impact on vaccine breakthrough infections and subsequent transmission in the…”
Get full text
Journal Article -
4
Epigenetic reprogramming of the zygote in mice and men: on your marks, get set, go
Published in Reproduction (Cambridge, England) (01-12-2016)“…Gametogenesis (spermatogenesis and oogenesis) is accompanied by the acquisition of gender-specific epigenetic marks, such as DNA methylation, histone…”
Get full text
Journal Article -
5
Does autonomous macrophage-driven inflammation promote alveolar damage in COVID-19?
Published in The European respiratory journal (01-12-2022)“…SARS-CoV-2 has caused devastating effects with over 550 million infections by July 2022 and approximately 6.4 million deaths [1]. Societal and economic impacts…”
Get full text
Journal Article -
6
Extravillous trophoblast and decidual natural killer cells: a remodelling partnership
Published in Human reproduction update (01-07-2012)“…During pregnancy, maternal uterine spiral arteries (SAs) are remodelled from minimal-flow, high-resistance vessels into larger diameter vessels with low…”
Get full text
Journal Article -
7
Severe COVID-19 versus multisystem inflammatory syndrome: comparing two critical outcomes of SARS-CoV-2 infection
Published in European respiratory review (31-03-2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with diverse host response immunodynamics and variable inflammatory…”
Get full text
Journal Article -
8
Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance
Published in The Journal of pathology (01-11-2012)“…During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells…”
Get full text
Journal Article -
9
Decidual natural killer cells regulate vessel stability: implications for impaired spiral artery remodelling
Published in Journal of reproductive immunology (01-08-2015)“…Highlights • dNK cells isolated from pregnancies with high or normal uterine artery resistance indices. • Normal-RI dNK cells activate ECs and destabilise…”
Get full text
Journal Article -
10
COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms
Published in Molecular systems biology (01-12-2021)Get full text
Journal Article -
11
Erratum To: COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms
Published in Molecular systems biology (23-12-2021)“…Graphical Abstract…”
Get full text
Journal Article