Search Results - "Fraser, Karen P."

NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time‐dependent and stochastic manner independently of CD94 and NKG2 by Fraser, Karen P., Gays, Frances, Robinson, John H., Beneden, Katrien van, Leclercq, Georges, Vance, Russell E., Raulet, David H., Brooks, Colin G.

“…NK cells developing in vitro from fetal progenitors in the presence of IL‐2 are phenotypically and functionally indistinguishable from mature adult NK cells,…”
Get full text

The Mouse Tumor Cell Lines EL4 and RMA Display Mosaic Expression of NK-Related and Certain Other Surface Molecules and Appear to Have a Common Origin by Gays, Frances, Unnikrishnan, Meera, Shrestha, Sunil, Fraser, Karen P, Brown, Adam R, Tristram, Colin M. G, Chrzanowska-Lightowlers, Zosia M. A, Brooks, Colin G

“…As a potential means for facilitating studies of NK cell-related molecules, we examined the expression of these molecules on a range of mouse tumor cell lines…”
Get full text

Functional Analysis of the Molecular Factors Controlling Qa1-Mediated Protection of Target Cells from NK Lysis by Gays, Frances, Fraser, Karen P, Toomey, Jennifer A, Diamond, Austin G, Millrain, Margaret M, Dyson, P. Julian, Brooks, Colin G

“…CD94/NKG2 receptors on mouse NK cells recognize the nonclassical class I molecule Qa1 and can deliver inhibitory signals that prevent NK cells from lysing…”
Get full text