Search Results - "Frascarelli, Sabina"
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Effect of Combined Levothyroxine (L-T4) and 3-Iodothyronamine (T1AM) Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism
Published in International journal of molecular sciences (08-09-2023)“…Mood alterations, anxiety, and cognitive impairments associated with adult-onset hypothyroidism often persist despite replacement treatment. In rodent models…”
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2
Tissue Distribution and Cardiac Metabolism of 3-Iodothyronamine
Published in Endocrinology (Philadelphia) (01-10-2010)“…3-Iodothyronamine (T1AM) is a novel relative of thyroid hormone, able to interact with specific G protein-coupled receptors, known as trace amine-associated…”
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3
Modulation of gene expression by 3-iodothyronamine: genetic evidence for a lipolytic pattern
Published in PloS one (07-11-2014)“…3-Iodothyronamine (T1AM) is an endogenous biogenic amine, structurally related to thyroid hormone, which is regarded as a novel chemical messenger. The…”
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4
3,5-Diiodo-l-Thyronine Increases Glucose Consumption in Cardiomyoblasts Without Affecting the Contractile Performance in Rat Heart
Published in Frontiers in endocrinology (Lausanne) (30-05-2018)“…3,5-diiodo-l-thyronine (T2) is an endogenous derivative of thyroid hormone that has been suggested to regulate energy expenditure, resting metabolic rate and…”
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5
Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function
Published in The FASEB journal (01-05-2007)“…3-iodothyronamine T₁AM is a novel endogenous thyroid hormone derivative that activates the G protein-coupled receptor known as trace anime-associated receptor…”
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3-Iodothyronamine and 3,5,3'-triiodo-L-thyronine reduce SIRT1 protein expression in the HepG2 cell line
Published in Hormone molecular biology and clinical investigation (02-03-2020)“…Background 3-Iodothyronamine (T1AM) is an endogenous messenger chemically related to thyroid hormone. Recent results indicate significant transcriptional…”
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Cardioprotective Effect of 3-Iodothyronamine in Perfused Rat Heart Subjected to Ischemia and Reperfusion
Published in Cardiovascular drugs and therapy (01-08-2011)“…3-iodothyronamine (T 1 AM) is an endogenous compound which shares structural and functional features with biogenic amines and is able to interact with a…”
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Vitamin D measurement and effect on outcome in a cohort of patients with heart failure
Published in Endocrine Connections (01-09-2018)“…Objectives The aims of this paper were to evaluate the levels of Vitamin D (VitD) in patients with heart failure (HF), compared to a control group, to assess…”
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Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart
Published in Basic research in cardiology (01-11-2003)“…Receptors for growth hormone secretagogues have been identified in cardiac tissue, but their functional role is unknown. We have investigated the effect of…”
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10
Uptake and metabolic effects of 3-iodothyronamine in hepatocytes
Published in Journal of endocrinology (01-04-2014)“…3-Iodothyronamine (T1AM) is an endogenous relative of thyroid hormone with profound metabolic effects. In different experimental models, T1AM increased blood…”
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11
Effect of Combined Levothyroxine Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism
Published in International journal of molecular sciences (01-09-2023)“…Mood alterations, anxiety, and cognitive impairments associated with adult-onset hypothyroidism often persist despite replacement treatment. In rodent models…”
Get full text
Journal Article -
12
Distribution of exogenous [125I]-3-iodothyronamine in mouse in vivo: relationship with trace amine-associated receptors
Published in Journal of endocrinology (01-06-2012)“…3-Iodothyronamine (T1AM) is a novel chemical messenger, structurally related to thyroid hormone, able to interact with G protein-coupled receptors known as…”
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13
Quantification of dehydroepiandrosterone in human serum on a routine basis: development and validation of a tandem mass spectrometry method based on a surrogate analyte
Published in Analytical and bioanalytical chemistry (2018)“…In the clinical laboratories, dehydroepiandrostenedione (DHEA) is usually quantified by immunoassay-based methods, which are often affected by cross-reactivity…”
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Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists
Published in Journal of medicinal chemistry (25-06-2015)“…Trace amine associated receptor 1 (TAAR1) is a G protein coupled receptor (GPCR) expressed in brain and periphery activated by a wide spectrum of agonists that…”
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15
Hypovitaminosis D in patients with heart failure: effects on functional capacity and patients’ survival
Published in Endocrine (01-12-2017)“…Chronic heart failure is a major cause of morbidity and mortality, but its prognosis remains poor. Vitamin D hormone has many extra-skeletal functions…”
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Ultrastructural Localization of Histidine-rich Glycoprotein in Skeletal Muscle Fibers: Colocalization With AMP Deaminase
Published in The journal of histochemistry and cytochemistry (01-02-2020)“…Histidine-rich glycoprotein (HRG) is a plasma protein synthesized by the liver. We have given the first evidence of a tissue localization of HRG demonstrating…”
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Cardioprotection by Ranolazine in Perfused Rat Heart
Published in Journal of cardiovascular pharmacology (01-12-2014)“…We used the isolated working rat model to evaluate the effect of therapeutic concentrations (5–10 μM) of ranolazine on contractile performance, oxygen…”
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Performance in Behavioral Testing in an Animal Model of Post-Surgical Hypoparathyroidism
Published in Journal of personalized medicine (01-02-2024)“…Hypoparathyroidism (HypoPT) is characterized by hypocalcemia and undetectable/inappropriately low PTH. Post-surgical HypoPT (PS-HypoPT) is the most common…”
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Effect of acute and chronic zofenopril administration on cardiac gene expression
Published in Molecular and cellular biochemistry (01-06-2011)“…We investigated whether acute and chronic administration of zofenopril, an angiotensin converting enzyme inhibitor, may modulate the expression of genes which…”
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Cardiac effects of trace amines: Pharmacological characterization of trace amine-associated receptors
Published in European journal of pharmacology (10-06-2008)“…Trace amine-associated receptors, a novel class of G-protein coupled receptors which respond to trace amines but not to classical biogenic amines, have been…”
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