Search Results - "Franzblau, S. G."

In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis by Upton, A M, Cho, S, Yang, T J, Kim, Y, Wang, Y, Lu, Y, Wang, B, Xu, J, Mdluli, K, Ma, Z, Franzblau, S G

“…Nitroimidazoles are a promising new class of antitubercular agents. The nitroimidazo-oxazole delamanid (OPC-67683, Deltyba) is in phase III trials for the…”
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Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium by COLLINS, L. A, FRANZBLAU, S. G

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Rapid and simple MTT method for rifampicin and isoniazid susceptibility testing of Mycobacterium tuberculosis by FOONGLADDA, S, ROENGSANTHIA, D, ARJRATTANAKOOL, W, CHUCHOTTAWORN, C, CHAIPRASERT, A, FRANZBLAU, S. G

“…The MTT method for rifampicin and isoniazid susceptibility testing of Mycobacterium tuberculosis was developed by using bacterial suspension prepared from…”
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Rapid, Low-Technology MIC Determination with Clinical Mycobacterium tuberculosis Isolates by Using the Microplate Alamar Blue Assay by FRANZBLAU, S. G, WITZIG, R. S, GILMAN, R. H, MCLAUGHLIN, J. C, TORRES, P, MADICO, G, HERNANDEZ, A, DEGNAN, M. T, COOK, M. B, QUENZER, V. K, FERGUSON, R. M

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Antimycobacterial plant terpenoids by Cantrell, C L, Franzblau, S G, Fischer, N H

“…Tuberculosis (TB), mainly caused by Mycobacterium tuberculosis, is the leading killer among all infectious diseases worldwide and is responsible for more than…”
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Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis by COLLINS, L. A, TORRERO, M. N, FRANZBLAU, S. G

“…An optimal assay for high-throughput screening for new antituberculosis agents would combine the microplate format and low cost of firefly luciferase reporter…”
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Development of an extraction method for mycobacterial metabolome analysis by Jaki, B.U., Franzblau, S.G., Cho, S.H., Pauli, G.F.

“…As a prerequisite for studying the intracellular metabolome of mycobacteria, several methods were evaluated for efficient breakage of the cell using…”
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Synthesis and evaluation of rifabutin analogs against Mycobacterium avium and H37Rv, MDR and NRP Mycobacterium tuberculosis by FIGUEIREDO, Ricardo, MOITEIRO, Cristina, CRUZ, M. Eugénia M, CURTO, M. Joao Marcelo, FRANZBLAU, S. G, OROZCO, H, AGUILAR, D, HERNANDEZ-PANDO, R, CEU COSTA, M, AUGUSTA MEDEIROS, M, ALMEIDA DA SILVA, P, RAMOS, D, SPIES, F, RIBEIRO, M. O, LOURENCO, M. Cristina S, JUNIOR, I. N, GASPAR, M. Manuela

“…Clinical utility of rifabutin 1 (RBT), a potent antibiotic used in multidrug regimens for tuberculosis (TB) as well as for infections caused by Mycobacterium…”
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Ethnobotany/ethnopharmacology and mass bioprospecting: Issues on intellectual property and benefit-sharing by Soejarto, D.D., Fong, H.H.S., Tan, G.T., Zhang, H.J., Ma, C.Y., Franzblau, S.G., Gyllenhaal, C., Riley, M.C., Kadushin, M.R., Pezzuto, J.M., Xuan, L.T., Hiep, N.T., Hung, N.V., Vu, B.M., Loc, P.K., Dac, L.X., Binh, L.T., Chien, N.Q., Hai, N.V., Bich, T.Q., Cuong, N.M., Southavong, B., Sydara, K., Bouamanivong, S., Ly, H.M., Thuy, Tran Van, Rose, W.C., Dietzman, G.R.

“…Ethnobotany/ethnopharmacology has contributed to the discovery of many important plant-derived drugs. Field explorations to seek and document…”
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Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Genetics of dTDP-Rhamnose Synthetic Enzymes and Development of a Microtiter Plate-Based Screen for Inhibitors of Conversion of dTDP-Glucose to dTDP-Rhamnose by Ma, Y, Stern, R J, Scherman, M S, Vissa, V D, Yan, W, Jones, V C, Zhang, F, Franzblau, S G, Lewis, W H, McNeil, M R

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Evaluation of a modified antimycobacterial susceptibility test using Middlebrook 7H10 agar containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride by Lee, S., Kong, D.H., Yun, S.H., Lee, K.R., Lee, K.P., Franzblau, S.G., Lee, E.Y., Chang, C.L.

“…A rapid and accurate antimycobacterial susceptibility test is essential for effective treatment of tuberculosis. The aim of this study was to evaluate a…”
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Use of receiver operating characteristic curves to assess the performance of a microdilution assay for determination of drug susceptibility of clinical isolates of Mycobacterium tuberculosis by LUNA-HERRERA, J, MARTINEZ-CABRERA, G, PARRA-MALDONADO, R, ENCISO-MORENO, J. A, TORRES-LOPEZ, J, QUESADA-PASCUAL, F, DELGADILLO-POLANCO, R, FRANZBLAU, S. G

“…The aim of this study was to apply receiver operating characteristic (ROC) analysis to the microplate Alamar blue assay, a recently developed alternative for…”
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Antimycobacterial Activity of Substituted Isosteres of Pyridine- and Pyrazinecarboxylic Acids by Wächter, Gerald A, Davis, Matt C, Martin, Arnold R, Franzblau, Scott G

“…Pyrazines and pyridines substituted with alkylated tetrazoles, esterified vinylogous carboxylic acids, and ketosulfides were synthesized as precursors of…”
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Isolation of 6-, 8-, and 10-gingerol from ginger rhizome by HPLC and preliminary evaluation of inhibition of Mycobacterium avium and Mycobacterium tuberculosis by Hiserodt, R.D. (The State University of New Jersey, NB, NJ.), Franzblau, S.G, Rosen, R.T

“…Diseases caused by Mycobacterium avium (M. avium) and Mycobacterium tuberculosis (M. tuberculosis) have reached pandemic proportions with some strains being…”
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Antimycobacterial Activity of Substituted Isosteres of Pyridine- and Pyrazinecarboxylic Acids. 2 by Gezginci, Mikail H, Martin, Arnold R, Franzblau, Scott G

“…Pyridines and pyrazines substituted with 1,2,4-oxadiazole-5-ones, 1,2,4-oxadiazole-5-thiones, and 1,3,4-oxathiazoline-2-ones were synthesized and tested…”
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Furoxan derivatives demonstrated in vivo efficacy by reducing Mycobacterium tuberculosis to undetectable levels in a mouse model of infection by de Souza, P.C., Fernandes, G.F.S., Marino, L.B., Ribeiro, C.M., Silva, P.B. da, Chorilli, M., Silva, C.S.P., Resende, F.A., Solcia, M.C., de Grandis, R.A., Costa, C.A.S., Cho, S.H., Wang, Y., Franzblau, S.G., dos Santos, J.L., Pavan, F.R.

“…[Display omitted] •New furoxan compounds lead to undetectable M. tuberculosis in a mouse model of infection.•High activity against MDR and…”
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Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities by Antoun, M. D., Ramos, Z., Vazques, J., Oquendo, I., Proctor, G. R., Gerena, L., Franzblau, S. G.

“…The emergence of resistant strains of Plasmodium falciparum and Mycobacterium tuberculosis underscores the need for novel drugs that are effective against…”
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Improved Green Fluorescent Protein Reporter Gene-Based Microplate Screening for Antituberculosis Compounds by Utilizing an Acetamidase Promoter by CHANGSEN, Chartchai, FRANZBLAU, Scott G, PALITTAPONGARNPIM, Prasit

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Antimycobacterial evaluation of germacranolides by FISCHER, N. H, TIANSHENG LU, CANTRELL, C. L, CASTANEDA-ACOSTA, J, QUIJANO, L, FRANZBLAU, S. G

“…The minimum inhibitory concentrations (MIC) against Mycobacterium tuberculosis and M. avium of parthenolide, costunolide, 1 (10)-epoxycostunolide and other…”
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A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents by Hurdle, Julian G., Lee, Robin B., Budha, Nageshwar R., Carson, Elizabeth I., Qi, Jianjun, Scherman, Michael S., Cho, Sang Hyun, McNeil, Michael R., Lenaerts, Anne J., Franzblau, Scott G., Meibohm, Bernd, Lee, Richard E.

“…Objectives Nitrofuranylamides (NFAs) are nitroaromatic compounds that have recently been discovered and have potent anti-tuberculosis (TB) activity. A…”
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