Search Results - "Franz, Kate M"
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Diverse intracellular pathogens activate type III interferon expression from peroxisomes
Published in Nature immunology (01-08-2014)“…Type III interferons have important antiviral functions, but they are poorly described compared to type I interferons. Kagan and colleagues demonstrate that…”
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STING-dependent translation inhibition restricts RNA virus replication
Published in Proceedings of the National Academy of Sciences - PNAS (27-02-2018)“…In mammalian cells, IFN responses that occur during RNA and DNA virus infections are activated by distinct signaling pathways. The RIG-I–like-receptors (RLRs)…”
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PRRs are watching you: Localization of innate sensing and signaling regulators
Published in Virology (New York, N.Y.) (01-05-2015)“…Abstract To prevent the spread of infection, an invading pathogen must first be recognized by the innate immune system. Host pattern recognition receptors…”
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Innate Immune Receptors as Competitive Determinants of Cell Fate
Published in Molecular cell (15-06-2017)“…Infections can cause a multitude of stresses on the host and microbe. To detect potential infections, the mammalian immune system utilizes several families of…”
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Multi-omic profiling reveals early immunological indicators for identifying COVID-19 Progressors
Published in Clinical immunology (Orlando, Fla.) (01-11-2023)“…We sought to better understand the immune response during the immediate post-diagnosis phase of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by…”
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Social, economic, and policy implications of organ preservation advances
Published in Current opinion in organ transplantation (01-06-2018)“…Despite over 60 years of progress in the field of since the first organ transplant, insufficient organ preservation capabilities still place profound…”
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Finding a needle in a haystack of needles – a productive hunt for interferon stimulated genes with antiviral activity
Published in Immunology and cell biology (01-03-2014)Get full text
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